Patents by Inventor Thomas Adamski
Thomas Adamski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11970590Abstract: Described herein are anionic phenylene oligomers and polymers, and devices including these materials. The oligomers and polymers can be prepared in a convenient and well-controlled manner, and can be used in cation exchange membranes. Also described is the controlled synthesis of anionic phenylene monomers and their use in synthesizing anionic oligomers and polymers, with precise control of the position and number of anionic groups.Type: GrantFiled: January 17, 2023Date of Patent: April 30, 2024Inventors: Steven Holdcroft, Thomas J. G. Skalski, Michael Adamski, Benjamin Britton, Timothy J. Peckham
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Publication number: 20240117132Abstract: Described herein are anionic phenylene oligomers and polymers, and devices including these materials. The oligomers and polymers can be prepared in a convenient and well-controlled manner, and can be used in cation exchange membranes. Also described is the controlled synthesis of anionic phenylene monomers and their use in synthesizing anionic oligomers and polymers, with precise control of the position and number of anionic groups.Type: ApplicationFiled: September 11, 2023Publication date: April 11, 2024Applicant: Simon Fraser UniversityInventors: Steven Holdcroft, Thomas J.G. Skalski, Michael Adamski, Benjamin Britton, Timothy J. Peckham
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Patent number: 11944819Abstract: Systems, devices, and techniques are described for analyzing evoked compound action potentials (ECAP) signals to assess the effect of a delivered electrical stimulation signal. In one example, a system includes a stimulation generator configured to deliver a stimulation pulse to a patient, sensing circuitry configured to sense an evoked compound action potential (ECAP) signal evoked from the stimulation pulse, and processing circuitry. The processing circuitry may be configured to determine a maximum value of a derivative of the ECAP signal, determine a minimum value of the derivative of the ECAP signal, determine, based on the maximum value of the derivative and the minimum value of the derivative, a characteristic value of the ECAP signal, and determine, based on the characteristic value of the ECAP signal, at least one parameter value at least partially defining electrical stimulation therapy to be delivered to the patient.Type: GrantFiled: July 9, 2020Date of Patent: April 2, 2024Assignee: Medtronic, Inc.Inventors: Robert A. Corey, Kristin N. Hageman, David A. Dinsmoor, Hank Bink, Christopher L. Pulliam, Thomas Adamski
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Publication number: 20240058600Abstract: Techniques are disclosed for delivering electrical stimulation therapy to a patient. In one example, a medical system delivers electrical stimulation therapy to a tissue of the patient via electrodes. The medical system determines a first change of a first sensed signal of the patient to movement by the patient and a second change of a second sensed signal of the patient to the movement by the patient. Based on the first change and the second change, the medical system selects one of the first sensed signal and the second sensed signal of the patient for controlling the electrical stimulation therapy. The medical system adjusts a level of at least one parameter of the electrical stimulation therapy based on the selected one of the first sensed signal and the second sensed signal.Type: ApplicationFiled: October 27, 2023Publication date: February 22, 2024Inventors: Scott R. Stanslaski, Timothy R. Abraham, Thomas Adamski, Timothy J. Denison, Robert S. Raike
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Publication number: 20240050736Abstract: Techniques are disclosed for delivering electrical stimulation therapy to a patient. In one example, a medical system delivers electrical stimulation therapy to a tissue of the patient via electrodes. The medical system determines a first change of a first sensed signal of the patient to movement by the patient and a second change of a second sensed signal of the patient to the movement by the patient. Based on the first change and the second change, the medical system selects one of the first sensed signal and the second sensed signal of the patient for controlling the electrical stimulation therapy. The medical system adjusts a level of at least one parameter of the electrical stimulation therapy based on the selected one of the first sensed signal and the second sensed signal.Type: ApplicationFiled: October 27, 2023Publication date: February 15, 2024Inventors: Scott R. Stanlaski, Timothy R. Abraham, Thomas Adamski, Timothy J. Denison, Robert S. Raike
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Publication number: 20230310841Abstract: Techniques are disclosed for defining a homeostatic window for controlling delivery of electrical stimulation therapy to a patient. In one example, a method includes generating and delivering electrical stimulation therapy to tissue of a patient via electrodes. Further, the method includes adjusting a level of a parameter of the electrical stimulation therapy such that a signal of the patient is not less than a lower bound and not greater than an upper bound. The lower bound is determined to be the magnitude of the signal while receiving electrical stimulation therapy sufficient to reduce one or more symptoms of a disease while the patient was receiving medication for reduction of the one or more symptoms. Further, the upper bound is determined to be the magnitude of the signal while receiving electrical stimulation therapy sufficient to reduce the one or more symptoms when the patient was not receiving the medication.Type: ApplicationFiled: June 5, 2023Publication date: October 5, 2023Inventors: Scott R. Stanslaski, Thomas Adamski, Duane L. Bourget, Timothy J. Denison, Benjamin P. Isaacson, Eric J. Panken, Jeffrey Herron
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Patent number: 11666750Abstract: Techniques are disclosed for defining a homeostatic window for controlling delivery of electrical stimulation therapy to a patient. In one example, a method includes generating and delivering electrical stimulation therapy to tissue of a patient via electrodes. Further, the method includes adjusting a level of a parameter of the electrical stimulation therapy such that a signal of the patient is not less than a lower bound and not greater than an upper bound. The lower bound is determined to be the magnitude of the signal while receiving electrical stimulation therapy sufficient to reduce one or more symptoms of a disease while the patient was receiving medication for reduction of the one or more symptoms. Further, the upper bound is determined to be the magnitude of the signal while receiving electrical stimulation therapy sufficient to reduce the one or more symptoms when the patient was not receiving the medication.Type: GrantFiled: November 30, 2020Date of Patent: June 6, 2023Assignee: Medtronic, Inc.Inventors: Scott R. Stanslaski, Thomas Adamski, Duane L. Bourget, Timothy J. Denison, Benjamin P. Isaacson, Eric J. Panken, Jeffrey Herron
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Publication number: 20220032065Abstract: Devices and methods provide for the sensing of physiological signals by providing a stimulation waveform that includes a stimulation pulse followed by an active recharge pulse to clear the charge in capacitors within the stimulation path. The active recharge pulse is followed by a period of passive recharge and then a period of no recharge. Non-neurological sources of artifacts within the sensed physiological signal may be handled by providing a brief period of passive recharge followed by a lengthy period of no recharge, which is made possible by the use of the active recharge pulse prior to the passive recharge. The period of no recharge removes any low impedance path to ground from the stimulation electrodes, which allows an amplifier of the sensing circuit to provide common mode rejection of non-neurological signals, such as cardiac signals, present at the sensing electrodes.Type: ApplicationFiled: October 14, 2021Publication date: February 3, 2022Inventors: Scott Stanslaski, Robert Devine, Timothy Denison, Vincent Roczniak, Todd Smith, Thomas Adamski
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Publication number: 20220008726Abstract: Systems, devices, and techniques are described for analyzing evoked compound action potentials (ECAP) signals to assess the effect of a delivered electrical stimulation signal. In one example, a system includes a stimulation generator configured to deliver a stimulation pulse to a patient, sensing circuitry configured to sense an evoked compound action potential (ECAP) signal evoked from the stimulation pulse, and processing circuitry. The processing circuitry may be configured to determine a maximum value of a derivative of the ECAP signal, determine a minimum value of the derivative of the ECAP signal, determine, based on the maximum value of the derivative and the minimum value of the derivative, a characteristic value of the ECAP signal, and determine, based on the characteristic value of the ECAP signal, at least one parameter value at least partially defining electrical stimulation therapy to be delivered to the patient.Type: ApplicationFiled: July 9, 2020Publication date: January 13, 2022Inventors: Robert A. Corey, Kristin N. Hageman, David A. Dinsmoor, Hank Bink, Christopher L. Pulliam, Thomas Adamski
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Patent number: 11160983Abstract: Devices and methods provide for the sensing of physiological signals by providing a stimulation waveform that includes a stimulation pulse followed by an active recharge pulse to clear the charge in capacitors within the stimulation path. The active recharge pulse is followed by a period of passive recharge and then a period of no recharge. Non-neurological sources of artifacts within the sensed physiological signal may be handled by providing a brief period of passive recharge followed by a lengthy period of no recharge, which is made possible by the use of the active recharge pulse prior to the passive recharge. The period of no recharge removes any low impedance path to ground from the stimulation electrodes, which allows an amplifier of the sensing circuit to provide common mode rejection of non-neurological signals, such as cardiac signals, present at the sensing electrodes.Type: GrantFiled: October 2, 2019Date of Patent: November 2, 2021Assignee: MEDTRONIC, INC.Inventors: Scott Stanslaski, Robert Devine, Timothy Denison, Vincent Roczniak, Todd Smith, Thomas Adamski
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Publication number: 20210322770Abstract: In some examples of selecting a target therapy delivery site for treating a patient condition, a relatively high frequency electrical stimulation signal is delivered to at least two areas within a first region (e.g., an anterior nucleus of the thalamus) of a brain of a patient, and changes in brain activity (e.g., as indicated by bioelectrical brain signals) within a second region (e.g., a hippocampus) of the brain of the patient in response to the delivered stimulation are determined. The target therapy delivery site, an electrode combination, or both, may be selected based on the changes in brain activity.Type: ApplicationFiled: June 30, 2021Publication date: October 21, 2021Inventors: Jonathon E. Giftakis, Timothy J. Denison, Paul H. Stypulkowski, Scott R. Stanslaski, Robert S. Raike, Mae Eng, David E. Linde, Thomas Adamski
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Patent number: 11077305Abstract: In some examples of selecting a target therapy delivery site for treating a patient condition, a relatively high frequency electrical stimulation signal is delivered to at least two areas within a first region (e.g., an anterior nucleus of the thalamus) of a brain of a patient, and changes in brain activity (e.g., as indicated by bioelectrical brain signals) within a second region (e.g., a hippocampus) of the brain of the patient in response to the delivered stimulation are determined. The target therapy delivery site, an electrode combination, or both, may be selected based on the changes in brain activity.Type: GrantFiled: September 8, 2017Date of Patent: August 3, 2021Assignee: MEDTRONIC, INC.Inventors: Jonathon E. Giftakis, Timothy J. Denison, Paul H. Stypulkowski, Scott R. Stanslaski, Robert S. Raike, Mae Eng, David E. Linde, Thomas Adamski
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Publication number: 20210196948Abstract: Techniques are disclosed for delivering electrical stimulation therapy to a patient. In one example, a medical system delivers electrical stimulation therapy to a tissue of the patient via electrodes. The medical system determines a first response of a first sensed signal of the patient to the electrical stimulation therapy and a second response of a second sensed signal of the patient to the electrical stimulation therapy. Based on the first response and the second response for controlling the electrical stimulation therapy, the medical system selects one of the first sensed signal and the second sensed signal of the patient. The medical system adjusts a level of at least one parameter of the electrical stimulation therapy based on the selected one of the first sensed signal and the second sensed signal.Type: ApplicationFiled: March 11, 2021Publication date: July 1, 2021Inventors: Scott R. Stanslaski, Timothy R. Abraham, Thomas Adamski, Timothy J. Denison, Robert S. Raike, Christopher L. Pulliam
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Publication number: 20210093851Abstract: Techniques are disclosed for defining a homeostatic window for controlling delivery of electrical stimulation therapy to a patient. In one example, a method includes generating and delivering electrical stimulation therapy to tissue of a patient via electrodes. Further, the method includes adjusting a level of a parameter of the electrical stimulation therapy such that a signal of the patient is not less than a lower bound and not greater than an upper bound. The lower bound is determined to be the magnitude of the signal while receiving electrical stimulation therapy sufficient to reduce one or more symptoms of a disease while the patient was receiving medication for reduction of the one or more symptoms. Further, the upper bound is determined to be the magnitude of the signal while receiving electrical stimulation therapy sufficient to reduce the one or more symptoms when the patient was not receiving the medication.Type: ApplicationFiled: November 30, 2020Publication date: April 1, 2021Inventors: Scott R. Stanslaski, Thomas Adamski, Duane L. Bourget, Timothy J. Denison, Benjamin P. Isaacson, Eric J. Panken, Jeffrey Herron
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Patent number: 10960202Abstract: Techniques are disclosed for delivering electrical stimulation therapy to a patient. In one example, a medical system delivers electrical stimulation therapy to a tissue of the patient via electrodes. The medical system determines a first change of a first sensed signal of the patient to movement by the patient and a second change of a second sensed signal of the patient to the movement by the patient. Based on the first change and the second change, the medical system selects one of the first sensed signal and the second sensed signal of the patient for controlling the electrical stimulation therapy. The medical system adjusts a level of at least one parameter of the electrical stimulation therapy based on the selected one of the first sensed signal and the second sensed signal.Type: GrantFiled: September 25, 2017Date of Patent: March 30, 2021Assignee: Medtronic, Inc.Inventors: Scott R. Stanslaski, Timothy R. Abraham, Thomas Adamski, Timothy J. Denison, Robert S. Raike
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Patent number: 10953222Abstract: Techniques are disclosed for delivering electrical stimulation therapy to a patient. In one example, a medical system delivers electrical stimulation therapy to a tissue of the patient via electrodes. The medical system determines a first response of a first sensed signal of the patient to the electrical stimulation therapy and a second response of a second sensed signal of the patient to the electrical stimulation therapy. Based on the first response and the second response for controlling the electrical stimulation therapy, the medical system selects one of the first sensed signal and the second sensed signal of the patient. The medical system adjusts a level of at least one parameter of the electrical stimulation therapy based on the selected one of the first sensed signal and the second sensed signal.Type: GrantFiled: September 25, 2017Date of Patent: March 23, 2021Assignee: MEDTRONIC, INC.Inventors: Scott R. Stanslaski, Timothy R. Abraham, Thomas Adamski, Timothy J. Denison, Robert S. Raike, Christopher Pulliam
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Publication number: 20210060331Abstract: Techniques are disclosed for delivering electrical stimulation therapy to a patient. In one example, a medical system delivers electrical stimulation therapy to a tissue of the patient via electrodes. The medical system determines a first change of a first sensed signal of the patient to movement by the patient and a second change of a second sensed signal of the patient to the movement by the patient. Based on the first change and the second change, the medical system selects one of the first sensed signal and the second sensed signal of the patient for controlling the electrical stimulation therapy. The medical system adjusts a level of at least one parameter of the electrical stimulation therapy based on the selected one of the first sensed signal and the second sensed signal.Type: ApplicationFiled: November 13, 2020Publication date: March 4, 2021Inventors: Scott R. Stanslaski, Timothy R. Abraham, Thomas Adamski, Timothy J. Denison, Robert S. Raike
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Patent number: 10864368Abstract: Techniques are disclosed for defining a homeostatic window for controlling delivery of electrical stimulation therapy to a patient. In one example, a method includes generating and delivering electrical stimulation therapy to tissue of a patient via electrodes. Further, the method includes adjusting a level of a parameter of the electrical stimulation therapy such that a signal of the patient is not less than a lower bound and not greater than an upper bound. The lower bound is determined to be the magnitude of the signal while receiving electrical stimulation therapy sufficient to reduce one or more symptoms of a disease while the patient was receiving medication for reduction of the one or more symptoms. Further, the upper bound is determined to be the magnitude of the signal while receiving electrical stimulation therapy sufficient to reduce the one or more symptoms when the patient was not receiving the medication.Type: GrantFiled: September 25, 2017Date of Patent: December 15, 2020Assignee: Medtronic, Inc.Inventors: Scott R. Stanslaski, Thomas Adamski, Duane L. Bourget, Timothy J. Denison, Benjamin P. Isaacson, Eric J. Panken, Jeffrey Herron
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Publication number: 20200230406Abstract: A method includes monitoring a sensor signal and classifying a physiological marker of a patient based upon the sensor signal. The method also includes generating a control signal based on the classified physiological marker, the control signal controlling an implantable stimulation device to provide the electrical stimulation at a target site within the patient. The method further includes adapting one or more of a manner in which processor circuitry classifies the physiological markers, generates the control signal, or one or more stimulation parameters of a stimulation program based on the classified physiological markers or patient input so as to automatically adjust one or more of timing or the stimulation parameters of the electrical stimulation.Type: ApplicationFiled: January 16, 2020Publication date: July 23, 2020Inventors: Thaddeus S. Brink, Thomas Adamski, Scott R. Stanslaski, Lance Zirpel, Jeffrey Herron
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Publication number: 20200030610Abstract: Devices and methods provide for the sensing of physiological signals by providing a stimulation waveform that includes a stimulation pulse followed by an active recharge pulse to clear the charge in capacitors within the stimulation path. The active recharge pulse is followed by a period of passive recharge and then a period of no recharge. Non-neurological sources of artifacts within the sensed physiological signal may be handled by providing a brief period of passive recharge followed by a lengthy period of no recharge, which is made possible by the use of the active recharge pulse prior to the passive recharge. The period of no recharge removes any low impedance path to ground from the stimulation electrodes, which allows an amplifier of the sensing circuit to provide common mode rejection of non-neurological signals, such as cardiac signals, present at the sensing electrodes.Type: ApplicationFiled: October 2, 2019Publication date: January 30, 2020Inventors: Scott Stanslaski, Robert Devine, Timothy Denison, Vincent Roczniak, Todd Smith, Thomas Adamski