Patents by Inventor Thomas Alava
Thomas Alava has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240011069Abstract: The present invention relates to a biosensor comprising a plurality of functionalized sets of carbon atoms in the sp2 hybridisation state, its method of preparation and its use, in particular for the detection of ecotoxicological risks, in particular the determination of the toxicity of substances present in an aqueous medium, as well as to the corresponding determination method.Type: ApplicationFiled: May 25, 2023Publication date: January 11, 2024Applicant: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVESInventors: Doriane EYVRARD, Thomas ALAVA
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Publication number: 20230304970Abstract: A method for controlling a submersible environmental sensor, the sensor including a support having a face which includes a sensitive zone configured to receive at least one species of interest (SOI), anti-fouling means configured to cause at least the sensitive zone to vibrate, and detection means for detecting a presence of the SOI on the sensitive zone, the detection means and the anti-fouling means being carried by the support, wherein the anti-fouling means includes actuators configured to cause the medium to vibrate in a standing mode with a wavelength 3-20 times the size of the SOI to confine the SOI on the sensitive zone, includes activating the anti-fouling means in a de-fouling mode, stopping the anti-fouling means, activating the anti-fouling means to confine the SOI in the sensitive zone, and stopping the anti-fouling means. The method also includes activating the detection means and stopping the detection means.Type: ApplicationFiled: June 17, 2021Publication date: September 28, 2023Applicant: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVESInventors: Fabrice CASSET, Thomas ALAVA
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Publication number: 20230236182Abstract: A sensor may include a prism having a first face; a metal first layer covering, via a contact face, the first face; a light source; and a matrix-array detector; the device may include a dielectric second layer on which rests a transistor including a sheet made of a two-dimensional material, intended to form a channel region, a front face of the sheet comprising a specific functionalization via which specific targets are liable to be adsorbed, the specific functionalization being suitable for placing the adsorbed specific targets at a smaller distance Dd below which detection via electrical measurement by means of the specific transistor and via measurement of resonance of surface plasmons is possible.Type: ApplicationFiled: May 26, 2021Publication date: July 27, 2023Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, UNIVERSITE GRENOBLE ALPES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Thomas ALAVA, Pascal MAILLEY, Yanxia HOU-BROUTIN, Loic LEROY
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Publication number: 20230081434Abstract: A concentration sensor for at least one biological species in the blood includes a support, at least one waveguide, and an optomechanical resonator suspended from the support. The optomechanical resonator is optically coupled to the waveguide, and the optomechanical resonator is configured to vibrate in volume mode and includes at least one face extending in the plane of the sensor and configured to receive molecules of the given species. At least the face includes a functionalisation layer specific to the species, the optomechanical resonator having a smaller dimension in a direction normal to the plane of the sensor compared with the dimensions of the said face.Type: ApplicationFiled: January 8, 2021Publication date: March 16, 2023Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE PARIS CITEInventors: Sebastien HENTZ, Thomas ALAVA, Ivan FAVERO
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Patent number: 11480480Abstract: A heat flux sensor comprising: an array of nanofilaments suspended with respect to a support, each nanofilament comprising an electrically conducting material, the array being able to be biased by an electric power source to circulate an electric current in each of the nanofilaments, at least one resonator of the nanoelectro-mechanical system (NEMS) type comprising: a beam consisting of a nanofilament forming a side of the array, an actuation device able to generate a vibration of the beam under the effect of an excitation signal, a detection device configured to measure a displacement of the beam during the vibration and emit an output signal having a resonance at the resonant frequency of the resonator, the resonant frequency depending on the intensity of the electric current flowing through the beam, a temperature variation of the array of heating nanofilaments induced by a variation in a characteristic of a fluid surrounding the array causing an intensity variation of the current flowing through the bType: GrantFiled: December 6, 2019Date of Patent: October 25, 2022Inventors: Eric Ollier, Thomas Alava, Kévin Benedetto, Carine Ladner, Eric Colinet
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Publication number: 20220299416Abstract: A sensor for sensing the concentration of at least one biological species in blood includes a support, at least one waveguide, and an optomechanical resonator hanging to the support. The optomechanical resonator is optically coupled to the waveguide. The optomechanical resonator is configured to vibrate in a volume mode and includes at least one face extending in the plane of the sensor and is configured to receive molecules of the given species. The optical resonator includes a body comprising an optical active area and an optical insulation layer deposited at least in line with the optical active area so as to confine at least partially an electromagnetic wave in the body.Type: ApplicationFiled: March 16, 2022Publication date: September 22, 2022Inventors: Marc Sansa Perna, Thomas Alava, Sebastien Hentz
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Publication number: 20220030855Abstract: The present invention relates to a set of carbon atoms in the sp2 hybridization state functionalized with an antibacterial antibody or a lectin, and to an antibacterial peptide, a method for preparing it, and its uses, in particular for rendering a surface antibacterial. The present invention is also directed to a material covered with such a functionalized set, as well as to a method for preparing it.Type: ApplicationFiled: July 23, 2021Publication date: February 3, 2022Applicant: Commissariat a I'Energie Atomique et aux Energies AlternativesInventors: Thomas Alava, Madhav Kumar
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Patent number: 11145549Abstract: Production of a transistor, the channel structure of which comprises at least one finned channel structure, the method comprising: forming, from a substrate (1), a molding block (3), forming, on the molding block, a thin layer (7) made from a given semiconductor or semi-metallic material, and consisting of one to ten atomic or molecular monolayers of two-dimensional crystal, withdrawing the molding block while retaining a portion (7a) of the thin layer extending against a lateral face of the molding block, said retained portion (7a) forming a fin that is capable of forming a channel structure of the transistor, producing a coating gate electrode against said fin.Type: GrantFiled: September 11, 2018Date of Patent: October 12, 2021Assignee: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVESInventors: Thomas Alava, Thomas Ernst, Zheng Han
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Publication number: 20210127454Abstract: The invention relates to a method for regulating, by means of a computer, a resistive element arranged to deice and/or demist a support, the method comprising: a) a loop for monitoring the temperature T and the moisture level H at the support; b) a deicing and/or demisting sequence which, as long as the temperature T and the moisture level H monitored by the monitoring loop a) are indicative of an absence of frost or mist on the support, keeps the resistive element inactive and, in the contrary case, demands, in a step b2), the circulation of a current I in the resistive element so that the latter dissipates a thermal power Pth, adjusted according to the temperature T and the moisture level H, and providing deicing or demisting of the support over a predetermined period Dp.Type: ApplicationFiled: October 19, 2020Publication date: April 29, 2021Applicant: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVESInventors: Thomas ALAVA, Zheng HAN
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Patent number: 10788470Abstract: A microelectromechanical gas sensor including a fixed part, at least one suspended part in relation to fixed part, at least one sensitive zone carried on the suspended part, the sensitive zone being able to adsorb/absorb and desorb gaseous species or families of gaseous species, a heater for heating at least the sensitive zone, a detector for detecting the adsorption/absorption and desorption of gaseous species or families of gaseous species on the sensitive zone, a controller of controlling the heater so that the heating is applied to at least the sensitive zone with one or more temperature profiles ensuring the adsorption/absorption and desorption of the gaseous species in a controlled manner so as to obtain an individual desorption of each species or families of gaseous species.Type: GrantFiled: December 22, 2016Date of Patent: September 29, 2020Assignee: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVESInventors: Valeria Toffoli, Thomas Alava, Bertrand Bourlon, Eric Ollier
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Publication number: 20200258783Abstract: Production of a transistor, the channel structure of which comprises at least one finned channel structure, the method comprising: forming, from a substrate (1), a molding block (3), forming, on the molding block, a thin layer (7) made from a given semiconductor or semi-metallic material, and consisting of one to ten atomic or molecular monolayers of two-dimensional crystal, withdrawing the molding block while retaining a portion (7a) of the thin layer extending against a lateral face of the molding block, said retained portion (7a) forming a fin that is capable of forming a channel structure of the transistor, producing a coating gate electrode against said fin.Type: ApplicationFiled: September 11, 2018Publication date: August 13, 2020Applicant: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVESInventors: Thomas ALAVA, Thomas ERNST, Zheng HAN
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Publication number: 20200182711Abstract: A heat flux sensor comprising: an array of nanofilaments suspended with respect to a support, each nanofilament comprising an electrically conducting material, the array being able to be biased by an electric power source to circulate an electric current in each of the nanofilaments, at least one resonator of the nanoelectro-mechanical system (NEMS) type comprising: a beam consisting of a nanofilament forming a side of the array, an actuation device able to generate a vibration of the beam under the effect of an excitation signal, a detection device configured to measure a displacement of the beam during the vibration and emit an output signal having a resonance at the resonant frequency of the resonator, the resonant frequency depending on the intensity of the electric current flowing through the beam, a temperature variation of the array of heating nanofilaments induced by a variation in a characteristic of a fluid surrounding the array causing an intensity variation of the current flowing through the bType: ApplicationFiled: December 6, 2019Publication date: June 11, 2020Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, Apix AnalyticsInventors: Eric Ollier, Thomas Alava, Kévin Benedetto, Carine Ladner, Eric Colinet
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Patent number: 10585074Abstract: Method of fabricating a microelectromechanical structure et comprising two elements suspended from a support, a cavity made in the support, said cavity having two different depths, including: fabrication of a mask on an element comprising a substrate and a structured layer formed on the substrate, said structured layer comprising the two elements that will be suspended above the cavity, the mask being formed above the structured layer, said mask comprising openings with different sections, the openings being distributed in two zones, each zone comprising openings with the same section, anisotropic etching of the element so as to define the two depths under the two suspended elements in the substrate through the structured layer, isotropic etching of the element so as to make the cavity under the suspended elements.Type: GrantFiled: January 17, 2018Date of Patent: March 10, 2020Assignee: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVESInventors: Bruno Fain, Carine Ladner, Thomas Alava
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Patent number: 10395907Abstract: A generator of an ion beam is provided, including an ionization chamber provided with an inlet of a fluid to be ionized; a source of ionizing particles configured to impact the fluid in an impact zone of the ionization chamber so as to generate ions; and an extractor of ions generated in a direction of an outlet zone of the generator, the extractor including at least two electrodes, a first electrode referred to as input electrode laterally bordering the impact zone, and at least one second electrode referred to as intermediate electrode located in the impact zone, the at least two electrodes being configured to generate a voltage gradient in the impact zone, with the voltage gradient being configured to direct the generated ions to the outlet zone of the generator.Type: GrantFiled: February 23, 2018Date of Patent: August 27, 2019Assignee: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVESInventors: Thomas Alava, Hadley Videlier, Frederic Progent, Laurent Duraffourg, Sebastien Vigne, Romain Mahieu
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Publication number: 20180254175Abstract: A generator of an ion beam is provided, including an ionisation chamber provided with an inlet of a fluid to be ionised; a source of ionising particles configured to impact the fluid in an impact zone of the ionisation chamber so as to generate ions; and an extractor of ions generated in a direction of an outlet zone of the generator, the extractor including at least two electrodes, a first electrode referred to as input electrode laterally bordering the impact zone, and at least one second electrode referred to as intermediate electrode located in the impact zone, the at least two electrodes being configured to generate a voltage gradient in the impact zone, with the voltage gradient being configured to direct the generated ions to the outlet zone of the generator.Type: ApplicationFiled: February 23, 2018Publication date: September 6, 2018Applicant: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVESInventors: Thomas ALAVA, Hadley VIDELIER, Frederic PROGENT, Laurent DURAFFOURG, Sebastien VIGNE
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Publication number: 20180202982Abstract: Method of fabricating a microelectromechanical structure et comprising two elements suspended from a support, a cavity made in the support, said cavity having two different depths, including: fabrication of a mask on an element comprising a substrate and a structured layer formed on the substrate, said structured layer comprising the two elements that will be suspended above the cavity, the mask being formed above the structured layer, said mask comprising openings with different sections, the openings being distributed in two zones, each zone comprising openings with the same section, anisotropic etching of the element so as to define the two depths under the two suspended elements in the substrate through the structured layer, isotropic etching of the element so as to make the cavity under the suspended elements.Type: ApplicationFiled: January 17, 2018Publication date: July 19, 2018Applicant: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVESInventors: Bruno FAIN, Garine Ladner, Thomas Alava
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Publication number: 20170184556Abstract: A microelectromechanical gas sensor including a fixed part, at least one suspended part in relation to fixed part, at least one sensitive zone carried on the suspended part, the sensitive zone being able to adsorb/absorb and desorb gaseous species or families of gaseous species, a heater for heating at least the sensitive zone, a detector for detecting the adsorption/absorption and desorption of gaseous species or families of gaseous species on the sensitive zone, a controller of controlling the heater so that the heating is applied to at least the sensitive zone with one or more temperature profiles ensuring the adsorption/absorption and desorption of the gaseous species in a controlled manner so as to obtain an individual desorption of each species or families of gaseous species.Type: ApplicationFiled: December 22, 2016Publication date: June 29, 2017Applicant: COMMISSARIAT A L`ENERGIE ATOMIQUE ET AUX ENERGIES AL TERNATIVESInventors: Valeria TOFFOLI, Thomas ALAVA, Bertrand BOURLON, Eric OLLIER
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Publication number: 20140121132Abstract: The present invention relates to a system for producing a nucleic acid molecule imaging array for use in high resolution imaging of individual nucleic acid molecules. The system includes a micro/nanostructured capture array having a hydrophobic surface having topographical features effective to assist in capillary-based trapping and elongation of individual nucleic acid molecules. The system also includes a transfer platform having a support and a hydrophobic substrate layered on the support. The transfer platform is effective to receive and capture, through solvent mediation, the trapped and elongated individual nucleic acid molecules from the micro/nanostructured capture array. The present invention also relates to a nucleic acid molecule imaging array, a transfer platform for use in preparing a nucleic acid molecule array, and a kit for producing a nucleic acid molecule imaging array for use in high resolution imaging of individual nucleic acid molecules.Type: ApplicationFiled: March 12, 2012Publication date: May 1, 2014Applicant: CORNELL UNIVERSITYInventors: Aline Cerf, Harold G. Craighead, Thomas Alava