Abstract: The specification relates to compounds of Formula (I): and pharmaceutically acceptable salts thereof. The specification also relates to processes and intermediates used for their preparation, pharmaceutical compositions containing them and their use in the treatment of cell proliferative disorders.

Abstract: An ultrasound imaging system includes a probe adapted to acquire ultrasound data, the probe including a probe head with a plurality of transducer elements, a housing defining a probe storage compartment adapted to receive the probe head, an ultraviolet light source disposed within the housing and configured to irradiate and sterilize the probe head when the probe head is placed in the probe storage compartment, and a screen attached to the housing and configured to display an ultrasound image based on the ultrasound data acquired with the probe. A method of sterilizing a probe includes inserting the probe head into the storage compartment defined by the housing and sterilizing the probe head with the ultraviolet light source.

Abstract: A system for disinfecting a fluid, including: a flow cell including one or more inlet ports and one or more outlet ports, wherein the flow cell is configured to communicate a fluid containing a biological contaminant from the one or more inlet ports to the one or more outlet portions through an interior portion thereof; and one or more point radiation sources disposed about the flow cell, wherein the one or more point radiation sources are operable for delivering radiation to the biological contaminant; wherein an interior surface of the flow cell is operable for reflecting the radiation delivered to the biological contaminant by the one or more point radiation sources; and wherein the interior surface of the flow cell is operable for reflecting the radiation delivered to the biological contaminant by the one or more point radiation sources such that a radiation intensity is uniform throughout the interior portion of the flow cell. In one exemplary embodiment, the flow cell is an integrating sphere.

Abstract: In some examples, systems, methods, and devices are described that generate exposure evaluations for dependent users. First data associated with a user and including objective values is accessed. Second data associated with the user and including subjective observations is accessed. The first data and the second data is used as input to evaluate one or more evaluation rules. Based on the evaluation, an exposure evaluation is generated. A notification is generated to include the exposure evaluation, which is provided to one or more destination entities.

Abstract: The present invention provides compounds of formula (I), and pharmaceutical compositions thereof.

Abstract: The invention provides a display interface in a social networking system that enables the presentation of information related to a user in a timeline or map view. The system accesses information about a user of a social networking system, including both data about the user and social network activities related to the user. The system then selects one or more of these pieces of data and/or activities from a certain time period and gathers them into timeline units based on their relatedness and their relevance to users. These timeline units are ranked by relevance to the user, and are used to generate a timeline or map view for the user containing visual representations of the timeline units organized by location or time. The timeline or map view is then provided to other users of the social networking system that wish to view information about the user.

Abstract: A method of magnetization reversal, time stable ferrimagnetic material, a product and a domain comprising said material, a system for magnetization reversal, and information storage. Therein, a ferrimagnetic material is one in which magnetic moments of the atoms on different sublattices are opposed, as in antiferromagnetism; however, in ferrimagnetic materials, the opposing moments are unequal and a spontaneous magnetization remains.

Abstract: A method and apparatus for forming a ribbon configured for use in forming a honeycomb structure when the ribbon is in a folded state. The ribbon comprises a first edge and a second edge. At least one portion of the first edge is not parallel to at least one portion of the second edge when the ribbon is in an unfolded state.

Abstract: A map interface presents a geographic map with markers identifying geographic locations associated with content items. When the geographic distance between two or more content items is less than a threshold distance, multiple content items are grouped to create an aggregated content item. Based on the geographic locations associated with the grouped content items, a geographic location is associated with the aggregated content item. A single marker identifies the geographic location for the aggregated content item on the geographic map. When a user viewing the map interface accesses the single marker, content selected from the content items combined to generated the aggregated content item is presented as well as the geographic location associated with the aggregated content item.

Abstract: Methods and systems for sensing properties of an object or entity utilize non-resistive contact sensors alone or in combination with other sensors. The sensor data is utilized for detecting and visualizing properties of one or more biological or non-biological objects or entities.

Abstract: A manufacturing execution system (MES) that provides tools for modeling and determining information about physical production lines made up of arrangements of entities. The MES includes configuration tools for modeling the entities in a physical production line. The MES also includes configuration tools for modeling the physical production line. Entity data models and line data models conform to the data structure of respective model templates. Line data models include line definition models and line layout models. Line layout models include an entity link model for each of the entities in the physical production line. The MES includes tools for dynamically determining the bottleneck for the physical production line. Other production metrics are also calculated using the MES.

Abstract: Systems and methods for managing access to a cache relate to determining one or more execute permissions associated with a write-address of a write-request to the cache. The cache may be a unified cache for storing data as well as instructions. If there is a write-miss in the cache for the write-request, a cache controller may determine whether to implement a write-allocate policy or a write-no-allocate policy for servicing the write-miss, based on the one or more execute permissions. The one or more execute permissions can relate to a privilege level associated with the write-address. Execute permissions of a producing agent which generated the write-request and an execute permission of a consuming agent which can execute from the write-address may be based on the privilege levels of the producing agent and the consuming agent, respectively.

Abstract: According to some embodiments, an automated resource allocation interface may receive, for a plurality of resource allocation categories, a selected sub-category from a set of potential sub-categories. Based on the selected sub-categories, a resource allocation score may be calculated, and the enterprise system may be assigned to a resource allocation level. A back-end application computer server may access electronic records representing a plurality of potential associations and, for each potential association, a set of attribute variables. Based on the set of attribute variables, a present total number of associations may be generated. Based on the assigned resource allocation level and the set of attribute variables, a future change to the total number of associations may be forecast. Based on the forecasted future change to the total number of associations, a predicted performance value associated with the enterprise system may be calculated and transmitted to generate a user interface display.

Abstract: In an aspect, a method of monitoring one or more symptoms of a person include repeating, over a period of time, the steps of: selecting, by the person, one or more symbolic representations corresponding to one or more symptoms from a predefined set of symbolic representations presented to the person; and electronically recording data regarding the one or more symbolic representations selected by the person such that the data is electronically accessible later for generating a history of the symptoms of the person over the period of time. The one or more symbolic representations corresponding to one or more symptoms is selected using an electronic device having a component for displaying the predefined set of symbolic representations that is coupled to a user input for receiving the selection of the one or more symbolic representations by the person.

Abstract: A system for disinfecting a fluid, including: a flow cell including one or more inlet ports and one or more outlet ports, wherein the flow cell is configured to communicate a fluid containing a biological contaminant from the one or more inlet ports to the one or more outlet portions through an interior portion thereof; and one or more point radiation sources disposed about the flow cell, wherein the one or more point radiation sources are operable for delivering radiation to the biological contaminant; wherein an interior surface of the flow cell is operable for reflecting the radiation delivered to the biological contaminant by the one or more point radiation sources; and wherein the interior surface of the flow cell is operable for reflecting the radiation delivered to the biological contaminant by the one or more point radiation sources such that a radiation intensity is uniform throughout the interior portion of the flow cell. In one exemplary embodiment, the flow cell is an integrating sphere.

Abstract: An apparatus (12) for treating water, in particular for removing surfactants from waste water, includes a vessel (14), defining an inlet (16) for receiving waste water containing air bubbles, and an outlet (20) for the exit of water, following treatment. Inside the vessel there is at least one tubular member (50) having a lower open end (52) into which the flow of waste water from the inlet may be directed in use. The tubular member (50) extends from the inlet towards a top of the vessel where an upper exit (54) from the tubular member is defined. In use, most un-aerated water entering the vessel through the inlet can exit the tubular member at the lower open end. Foam formed in the water by the air bubbles may travel up the tubular member to the upper exit, which is preferably located above the water level (60) in the vessel.

Abstract: This invention relates to apparatus and systems for providing home and building security and condition monitoring. More particularly, the invention relates to a plurality of devices, including intelligent, multi-sensing, network-connected devices, that communicate dynamically with each other and a remote server.

Abstract: The present application relates methods for treating a depressive symptom comprising administering an effective amount of a ? opioid receptor agonist or a pharmaceutically acceptable salt thereof to a subject in need thereof. Non-limiting examples of such agonist include the compounds of Formulas I, II, III, and IV, as well as the compounds of Table A.

Abstract: Delays due to waiting for operands that will not be used by a select operand instruction, are alleviated based on an early recognition that such operand data is not required in order to complete the processing of the select operand instruction. At appropriate points prior to execution, determinations are made regarding a selection criterion or criteria specified by the select operand instruction, conditions that affect the selection criteria, and the availability of operands. A hold circuit uses the determinations to control the activation and release of a hold signal that controls processor pipeline stalls. A stall required to wait for operand data is skipped or a stall is terminated early, if the selected operand is available even though the other operand, that will not be used, is not available. A stall due to waiting for operands is maintained until the selection criteria is met and the selected operand is fetched and made available.

Abstract: A dynamic scheduler is provided that schedules tasks for a plurality of cores based upon current operating characteristics for the cores. The current operating characteristics include a predicted leakage current for each core based upon an analytical model.