Patents by Inventor Thomas Antonsson

Thomas Antonsson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PYRIDINE COMPOUNDS AND THEIR USE AS P2Y12 ANTAGONISTS
    Publication number: 20100137277
    Abstract: The present invention relates to certain new pyridin analogues of Formula (I) to processes for preparing such compounds, to their utility as P2Y12 inhibitors and as anti-trombotic agents etc, their use as medicaments in cardiovascular diseases as well as pharmaceutical compositions containing them.
    Type: Application
    Filed: January 11, 2008
    Publication date: June 3, 2010
    Applicant: ASTRAZENECA AB
    Inventors: Thomas Antonsson, Peter Bach, David Brown, Ruth Bylund, Fabrizio Giordanetto, Johan Johansson
  • New Pyridine Analogues III
    Publication number: 20100069350
    Abstract: The present invention relates to certain new pyridin analogues of Formula (I), to processes for preparing such compounds, to their utility as P2Y12 inhibitors and as anti-trombotic agents etc, their use as medicaments in cardiovascular diseases as well as pharmaceutical compositions containing them.
    Type: Application
    Filed: July 2, 2007
    Publication date: March 18, 2010
    Applicant: ASTRAZENECA AB
    Inventors: Thomas Antonsson, Peter Bach, David Brown, Ruth Bylund, Fabrizio Giordanetto, Lotta Jakobsson, Johan Johansson
  • New Pyridine Analogues X 161
    Publication number: 20090018166
    Abstract: The present invention relates to certain new pyridin analogues of Formula (I) to processes for preparing such compounds, to their utility as P2Y12 inhibitors and as anti-trombotic agents etc, their use as medicaments in cardiovascular diseases as well as pharmaceutical compositions containing them.
    Type: Application
    Filed: January 11, 2008
    Publication date: January 15, 2009
    Applicant: ASTRAZENECA AB
    Inventors: Kosrat Amin, Thomas Antonsson, Christoffer Bengtsson, David Brown, Ruth Bylund, Daniel Hovdal, Fabrizio Giordanetto, Johan Johansson
  • New Pyridine Analogues VIII 518
    Publication number: 20080200448
    Abstract: The present invention relates to certain new pyridin analogues of Formula (I) to processes for preparing such compounds, to their utility as P2Y12 inhibitors and as anti-trombotic agents etc, their use as medicaments in cardiovascular diseases as well as pharmaceutical compositions containing them.
    Type: Application
    Filed: January 11, 2008
    Publication date: August 21, 2008
    Applicant: ASTRAZENECA AB
    Inventors: Thomas Antonsson, Peter Bach, Kay Brickmann, Ruth Bylund, Fabrizio Giordanetto, Johan Johansson, Fredrik Zetterberg
  • New Pyridine Analogues VII 543
    Publication number: 20080176827
    Abstract: The present invention relates to certain new pyridin analogues of Formula (I) to processes for preparing such compounds, to their utility as P2Y12 inhibitors and as anti-trombotic agents etc, their use as medicaments in cardiovascular diseases as well as pharmaceutical compositions containing them.
    Type: Application
    Filed: January 11, 2008
    Publication date: July 24, 2008
    Applicant: ASTRAZENECA AB
    Inventors: Thomas Antonsson, Peter Bach, Kay Brickmann, Ruth Bylund, Fabrizio Giordanetto, Johan Johansson, Fredrik Zetterberg
  • New Pyridine Analogues IX 519
    Publication number: 20080171732
    Abstract: The present invention relates to certain new pyridin analogues of Formula (I) to processes for preparing such compounds, to their utility as P2Y12 inhibitors and as anti-trombotic agents etc, their use as medicaments in cardiovascular diseases as well as pharmaceutical compositions containing them.
    Type: Application
    Filed: January 11, 2008
    Publication date: July 17, 2008
    Applicant: AstraZeneca AB
    Inventors: Thomas Antonsson, Ruth Bylund, Johan Johansson, Peter Bach, David Brown, Fabrizio Giordanetto
  • Compounds 614
    Publication number: 20080146538
    Abstract: The present invention relates to new compounds of formula I, to pharmaceutical compositions comprising said compounds, and to the use of said compounds in therapy. The present invention further relates to processes for the preparation of compounds of formula I.
    Type: Application
    Filed: December 19, 2007
    Publication date: June 19, 2008
    Inventor: Thomas Antonsson
  • Prodrugs of thrombin inhibitors
    Patent number: 7354905
    Abstract: There is provided compounds of formula I, R1O(O)C—CH2—(R)Cgl-Aze-Pab-R2I wherein R1 and R2 have meanings given in the description, which are useful as prodrugs of inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (eg thrombosis) or as anticoagulants.
    Type: Grant
    Filed: February 12, 2004
    Date of Patent: April 8, 2008
    Assignee: AstraZeneca AB
    Inventors: Thomas Antonsson, David Gustafsson, Kurt-Jürgen Hoffmann, Jan-Erik Nyström, Henrik Sörensen, Mikael Sellén
  • New Pyridine Analogues III
    Publication number: 20080039437
    Abstract: The present invention relates to certain new pyridin analogues of Formula (I) to processes for preparing such compounds, to their utility as P2Y12 inhibitors and as anti-thrombotic agents etc, their use as medicaments in cardiovascular diseases as well as pharmaceutical compositions containing them.
    Type: Application
    Filed: July 2, 2007
    Publication date: February 14, 2008
    Applicant: ASTRAZENECA AB
    Inventors: Thomas Antonsson, Peter Bach, David Brown, Ruth Bylund, Fabrizio Giordanetto, Lotta Jakobsson, Johan Johansson
  • Amidino derivatives and their use as thrombin inhibitors
    Patent number: 7074820
    Abstract: There is provided compounds of formula I, wherein R1, R2, R3, Y, n and B have meanings given in the description which are useful as competitive inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants.
    Type: Grant
    Filed: April 23, 2001
    Date of Patent: July 11, 2006
    Assignee: AstraZeneca AB
    Inventor: Thomas Antonsson
  • Prodrugs of thrombin inhibitors
    Publication number: 20040162410
    Abstract: There is provided compounds of formula I,
    Type: Application
    Filed: February 12, 2004
    Publication date: August 19, 2004
    Applicant: AstraZeneca AB
    Inventors: Thomas Antonsson, David Gustafsson, Kurt-Jurgen Hoffmann, Jan-Erik Nystrom, Henrik Sorensen, Mikael Sellen
  • Prodrugs of thrombin inhibitors
    Publication number: 20020142968
    Abstract: There is provided compounds of formula I,
    Type: Application
    Filed: February 14, 2002
    Publication date: October 3, 2002
    Applicant: AstraZeneca AB
    Inventors: Thomas Antonsson, David Gustafsson, Kurt-Jurgen Hoffmann, Jan-Erik Nystrom, Henrik Sorensen, Mikael Sellen
  • Amidino derivatives and their use as thrombin inhibitors
    Publication number: 20020040043
    Abstract: There is provided compounds of formula I, 1
    Type: Application
    Filed: April 23, 2001
    Publication date: April 4, 2002
    Inventor: Thomas Antonsson
  • Prodrugs of thrombin inhibitors
    Patent number: 6262028
    Abstract: There is provided compounds of formula I, R1O(O)C—CH2—(R)Cgl—Aze—Pab—R  I wherein R1 and R2 have meanings given in the description, which are useful as prodrugs of inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (eg thrombosis) or as anticoagulants.
    Type: Grant
    Filed: July 15, 1999
    Date of Patent: July 17, 2001
    Assignee: AstraZeneca AB
    Inventors: Thomas Antonsson, David Gustafsson, Kurt-Jürgen Hoffmann, Jan-Erik Nyström, Henrik Sörensen, Mikael Sellén
  • Amidino derivatives and their use as thrombin inhibitors
    Patent number: 6221898
    Abstract: There is provided compounds of formula I, wherein R1, R2, R3, Y, n and B have meanings given in the description which are useful as competitive inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants.
    Type: Grant
    Filed: August 29, 1997
    Date of Patent: April 24, 2001
    Assignee: Astra Aktiebolag
    Inventor: Thomas Antonsson