Abstract: A framework for safely operating autonomous machinery, such as vehicles and other heavy equipment, in an in-field or off-road environment, includes detecting, identifying, classifying and tracking objects and/or terrain characteristics from on-board sensors that capture images in front and around the autonomous machinery as it performs agricultural or other activities. The framework generates commands for navigational control of the autonomous machinery in response to perceived objects and terrain impacting safe operation. The framework processes image data and range data in multiple fields of view around the autonomous equipment to discern objects and terrain, and applies artificial intelligence techniques in one or more neural networks to accurately interpret this data for enabling such safe operation.

Abstract: The present invention concerns new nucleic acid molecules which may be used in many applications, and methods for making the same. These nucleic acid molecules are preferably DNA vectors, optionally DNA expression vectors. The nucleic acid molecules are able to target the vector to a specific cellular location, such as the nucleus, due to the presence of one or more particular binding motifs within the nucleic acid molecule itself. Thus, the nucleic acid molecules of the invention may also be described as targeted delivery vectors, notably self-targeted delivery vectors or smart delivery vectors.

Abstract: A framework for safely operating autonomous machinery, such as vehicles and other heavy equipment, in an in-field or off-road environment, includes detecting, identifying, classifying and tracking objects and/or terrain characteristics from on-board sensors that capture images in front and around the autonomous machinery as it performs agricultural or other activities. The framework generates commands for navigational control of the autonomous machinery in response to perceived objects and terrain impacting safe operation. The framework processes image data and range data in multiple fields of view around the autonomous equipment to discern objects and terrain, and applies artificial intelligence techniques in one or more neural networks to accurately interpret this data for enabling such safe operation.

Abstract: The present invention discloses a restaurant-based point of sales system. The restaurant-based point of sales system mainly comprises a cloud-based point of sales system, a cloud-based print service system and a hybrid-cloud application. Here, the cloud-based point of sales system is configured to record an order whenever a diner orders food at a restaurant. The cloud-based print service system is configured to generate one or more print orders based on the recorded diner orders. The hybrid-cloud application is installed on an end user device implemented in a restaurant to communicate with a cloud-based print service system to facilitate remote printing in parallel for every transaction. The hybrid-cloud application maintains routing rules to check one or more printers available on the local network and to print invoice/bill, one or more items at different printers in one or more kitchen stations in parallel for every transaction.

Abstract: Control systems and methods for coordinating multiple agricultural machines for operation on an agricultural field are provided. Each machine may receive field data for an agricultural field that optionally includes a plurality of pre-defined swaths. Each machine may receive state data from other machine(s). The state data for the other machine(s) may include a next swath and a current swath. Each machine may, after an indication of a start of its current swath, determine a next swath based on open swaths and the state data for the other machine(s). A next swath may also be determined using vehicle kinematic data, and conflicts between machines may be resolved.

Abstract: The present invention discloses a restaurant-based point of sales system. The restaurant-based point of sales system mainly comprises a cloud-based point of sales system, a cloud-based print service system and a hybrid-cloud application. Here, the cloud-based point of sales system is configured to record an order whenever a diner orders food at a restaurant. The cloud-based print service system is configured to generate one or more print orders based on the recorded diner orders. The hybrid-cloud application is installed on an end user device implemented in a restaurant to communicate with a cloud-based print service system to facilitate remote printing in parallel for every transaction. The hybrid-cloud application maintains routing rules to check one or more printers available on the local network and to print invoice/bill, one or more items at different printers in one or more kitchen stations in parallel for every transaction.

Abstract: The present invention concerns new artificially synthesized single stranded nucleic acid molecules which may be used in many applications, and templates and methods for making the same. There are a multitude of uses for single stranded nucleic acid molecules, including but not limited to vectors for the delivery of sequences (for example a gene sequence, or a template for gene editing, gene knock-in or knock-down) or in bioengineering, for example as for constructing highly ordered materials from nanoparticle building blocks.

Abstract: A framework for safely operating autonomous machinery, such as vehicles and other heavy equipment, in an in-field or off-road environment, includes detecting, identifying, and tracking objects from on-board sensors configured with the autonomous machinery as it performs activities in either an agricultural setting or a transportation environment. The framework generates commands for navigational control of autonomously-operated vehicles in response to detected objects and predicted tracks thereof for safe operation in the performance of those activities. The framework processes image data and range data in multiple fields of view around the autonomously-operated to discern and track objects in a deep learning to accurately interpret this data for determining and effecting such navigational control.

Abstract: The present invention relates to an improved process for synthesis of deoxyribonucleic acid (DNA), in particular cell-free enzymatic synthesis of DNA, preferably on a large scale, with an improved yield and/or with an improved efficiency. The species of cation present in the nucleotide salt as the counter-ion is critical to the yield, efficiency and fidelity of high yielding enzymatic DNA synthesis reaction. The processes herein use alternative cations as counter-ions for the ionic nucleotides, permitting the use of higher concentrations of nucleotides in DNA synthesis, and further allowing for more favourable reaction conditions to be used.

Abstract: A framework for safely operating autonomous machinery, such as vehicles and other heavy equipment, in an in-field or off-road environment, includes detecting, identifying, classifying and tracking objects and/or terrain characteristics from on-board sensors that capture images in front and around the autonomous machinery as it performs agricultural or other activities. The framework generates commands for navigational control of the autonomous machinery in response to perceived objects and terrain impacting safe operation. The framework processes image data and range data in multiple fields of view around the autonomous equipment to discern objects and terrain, and applies artificial intelligence techniques in one or more neural networks to accurately interpret this data for enabling such safe operation.

Abstract: A framework for safely operating autonomous machinery, such as vehicles and other heavy equipment, in an in-field or off-road environment, includes detecting, identifying, classifying and tracking objects and/or terrain characteristics from on-board sensors that capture images in front and around the autonomous machinery as it performs agricultural or other activities. The framework generates commands for navigational control of the autonomous machinery in response to perceived objects and terrain impacting safe operation. The framework processes image data and range data in multiple fields of view around the autonomous equipment to discern objects and terrain, and applies artificial intelligence techniques in one or more neural networks to accurately interpret this data for enabling such safe operation.

Abstract: A filter media construction wherein at least two layers of a substantially open spacer and at least two layers of a filter media/material are combined in an alternating sequence and coiled around a core to form at least two distinct, continuous or segmented, coil-shaped fluid flow channels that are contiguous but separated by the filter media in the radial direction and extend axially from an inlet side to an outlet side of the filter media construction preventing direct fluid flow between the clean and dirty sides of the filter media construction. The spacer maintains substantially uniform width of the flow channels in the flow direction providing substantially uniform fluid flow. One flow channel is closed to fluid flow at the inlet side forming the clean side and the other flow channel is closed to fluid flow at the outlet side forming the dirty side of the filter media construction.

Abstract: A framework for safely operating autonomous machinery, such as vehicles and other heavy equipment, in an in-field or off-road environment, includes detecting, identifying, classifying and tracking objects and/or terrain characteristics from on-board sensors that capture images in front and around the autonomous machinery as it performs agricultural or other activities. The framework generates commands for navigational control of the autonomous machinery in response to perceived objects and terrain impacting safe operation. The framework processes image data and range data in multiple fields of view around the autonomous equipment to discern objects and terrain, and applies artificial intelligence techniques in one or more neural networks to accurately interpret this data for enabling such safe operation.

Abstract: A filter media construction wherein at least two layers of a substantially open spacer and at least two layers of a filter media/material are combined in an alternating sequence and coiled around a core to form at least two distinct, continuous or segmented, coil-shaped fluid flow channels that are contiguous but separated by the filter media in the radial direction and extend axially from an inlet side to an outlet side of the filter media construction preventing direct fluid flow between the clean and dirty sides of the filter media construction. The spacer maintains substantially uniform width of the flow channels in the flow direction providing substantially uniform fluid flow. One flow channel is closed to fluid flow at the inlet side forming the clean side and the other flow channel is closed to fluid flow at the outlet side forming the dirty side of the filter media construction.

Abstract: The present invention relates to drug targets for Burkholderia pseudomallei. The invention provides a crystalline polypeptide derived from Burkholderia pseudomallei comprising the amino acid sequence set forth in SEQ ID NO: 1. Also provided are methods for co-crystallizing a binary enoyl-acyl carrier protein reductase (FabI) with a potential inhibitor of an FabI activity and for identifying an inhibitor of an activity of enoyl-acyl carrier protein reductase (FabI). A representative example of such a crystalline structure is a BpmFabI:AFN-1252 complex.

Abstract: The present invention relates to 5-substituted indole derivatives of formula (I): having inhibitory potential of dipeptidyl peptidase IV (DPP IV) enzyme where x and R1 are defined as defined in the specification