Abstract: A multi-layer dressing is disclosed. The dressing includes at least a primary layer comprised of a first layer, a transparent layer and a release liner. The first layer has an opening therethrough. The transparent layer is configured to cover the opening in the first layer. At least one of the first layer and the transparent layer includes a bottom adhesive surface. The release liner is attached to at least a portion of the bottom adhesive surface. The release liner is configured to provide an unobstructed view through the opening when the release liner is attached to the bottom adhesive surface. An optional closure piece is also disclosed, wherein the closure piece may be selectively altered to accommodate various sized catheter devise.