Abstract: An expandable locker shelf is disclosed that can be placed between two substantially vertical members, such as in a locker. The expandable shelf includes a first section having a rack, a second section, and a lever arm having a pinion. The first and second sections are aligned to engage the pinion with the rack. The lever arm enables the user to provide sufficient torque on the pinion to bias the first and second sections between the two substantially vertical members. The expandable locker shelf is locked between the two substantially vertical walls by engaging the lever arm with a retaining post.

Abstract: An expandable locker shelf is disclosed that can be placed between two substantially vertical members, such as in a locker. The expandable shelf includes a first section having a rack, a second section, and a lever arm having a pinion. The first and second sections are aligned to engage the pinion with the rack. The lever arm enables the user to provide sufficient torque on the pinion to bias the first and second sections between the two substantially vertical members. The expandable locker shelf is locked between the two substantially vertical walls by engaging the lever arm with a retaining post.

Abstract: A target-specific gene delivery system is made of enzymatically degradable gelatin and nucleic acids (DNA or RNA) microparticles with a linking moiety or a targeting ligand attached to the surface. The delivery system can be made by a simple method. Targeting ligands can be attached to the microparticle directly or via a linking moiety. The linkage design allows the attachment of any molecule onto the microparticle surface including antibodies, cell adhesion molecules, hormones and other cell-specific ligands.

Abstract: A target-specific gene delivery system is made of enzymatically degradable gelatin and nucleic acids (DNA or RNA) microparticles with a linking moiety or a targeting ligand attached to the surface. The delivery system can be made by a simple method. Targeting ligands can be attached to the microparticle directly or via a linking moiety. The linkage design allows the attachment of any molecule onto the microparticle surface including antibodies, cell adhesion molecules, hormones and other cell-specific ligands.

Abstract: A gene delivery system is made of enzymatically degradable polymeric cation and nucleic acid (DNA or RNA) nanospheres optionally with a linking moiety or a targeting ligand attached to the surface. The delivery system can be made by a simple method of coacervation. Targeting ligands can be attached to the nanosphere directly or via a linking moiety. The linkage design allows the attachment of any molecule onto the nanosphere surface including antibodies, cell adhesion molecules, hormones and other cell-specific ligands.

Abstract: The inventors have discovered a targeting signal that will direct proteins to the endosomal/lysosomal compartment, and they have demonstrated that chimeric proteins containing a luminal antigenic domain and a cytoplasmic endosomal/lysosomal targeting signal will effectively target antigens to that compartment, where the antigenic domain is processed and peptides from it are presented on the cell surface in association with major histocompatibility (MHC) class II molecules. Chimeric DNA encoding the antigen of interest, linked to an endosomal/lysosomal targeting sequence, inserted in an immunization vector, can introduce the chimeric genes into cells, where the recombinant antigens are expressed and targeted to the endosomal/lysosomal compartment. As a result, the antigens associate more efficiently with MHC class II molecules, providing enhanced in vivo stimulation of CD4.sup.+ T cells specific for the recombinant antigen.