Abstract: A shield device particularly useful in conjunction with a medicine containing vial or ampule to prevent medicine from spraying out of the vial as a hypodermic needle is extracted from the vial seal. The shield device includes a enclosure having a collapsable wall structure. One end of the shield device is formed with an opening for receiving the neck of the vial and sealing around the vial neck. The other end of the shield device from the vial neck receiving opening is formed with an aperture which is covered by a puncturable seal similar to the seal covering the opening into the vial neck. In use, the vial neck is inserted through the opening into the shield. Maintaining the shield device in the collapsed position with the shield seal in overlaying alignment with the vial seal, the needle of a hypodermic syringe is inserted through the shield seal and the vial seal, and into the vial for filling the vial with medicament or extracting medicament from the vial.