Abstract: Provided herein are chimeric receptors, engineered cells and pharmaceutical compositions for enhancement of long-term clearance of protein aggregates in the central nervous system via phagocytosis or engulfment. Further provided herein are methods of treatment of subjects suffering from, or diagnosed with, a neurodegenerative disease by administering these receptors, modified cells, and/or pharmaceutical compositions. Administration of one or more, or a plurality of these modified cells, to a subject may provide treatment of a neurodegenerative disease such as Alzheimer's Disease (AD) or Parkinson's Disease (PD). Advantageously, the modified cells, pharmaceutical compositions, and methods of the present disclosure meet existing needs in the art by providing clearance of accumulations of protein aggregates in brain tissue in PD and AD pathologies.

Abstract: Apparatus for applying an anaerobic adhesive to the inside of the necks of cartridge cases preparatory to insertion of bullets therein to provide a seal between the inside of the necks and the bullets, the cases being held standing on end, mouth end up, in a holder arranged in a rank and file format, the holder being indexed to bring successive rows of cases under a set of adhesive dispensing nozzles which are lowered for entry of the tips of the nozzles into the upper ends of the cases in a row.

Abstract: Mixing means comprising a disposable static-type mixer having opposed walls of sheet material secured to one another in a pattern such as to establish a flow path therethrough having a plurality of inlets at one end thereof for entry of the materials to be mixed (e.g., two resins forming a two-part plastic foam), an outlet at the other end thereof for exit of the mixture, and a plurality of flow passages between the inlet and the outlets. The flow passages cross one another at a plurality of intersections between the inlets and the outlet for mixing the materials flowing through the passages to the outlet.