Patents by Inventor Thomas Bar

Thomas Bar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12142907
    Abstract: An overcurrent protection device is for protecting a load arranged in a DC grid. The load is coupled to a supply busbar, which is connectable to a supply potential of the DC grid, in the DC grid via the overcurrent protection device. The overcurrent protection device is designed to ascertain a current trigger value based upon a detected value of a current flowing through the overcurrent protection device and a trigger characteristic which is assigned to the load and is based on the current; compare the current trigger value with a threshold, and either trigger the overcurrent protection device or not, based upon the result of the comparison. The current is taken into consideration together with a first or a second factor in the trigger characteristic based upon the current direction.
    Type: Grant
    Filed: May 15, 2020
    Date of Patent: November 12, 2024
    Assignee: SIEMENS AKTIENGESELLSCHAFT
    Inventors: Klaus Behringer, Wolfgang Feil, Peter Kaluza, Annemarie Lehmeier, Matthias Meier, Josef Burger, Thomas Bär
  • Publication number: 20220231497
    Abstract: An overcurrent protection device is for protecting a load arranged in a DC grid. The load is coupled to a supply busbar, which is connectable to a supply potential of the DC grid, in the DC grid via the overcurrent protection device. The overcurrent protection device is designed to ascertain a current trigger value based upon a detected value of a current flowing through the overcurrent protection device and a trigger characteristic which is assigned to the load and is based on the current; compare the current trigger value with a threshold, and either trigger the overcurrent protection device or not, based upon the result of the comparison. The current is taken into consideration together with a first or a second factor in the trigger characteristic based upon the current direction.
    Type: Application
    Filed: May 15, 2020
    Publication date: July 21, 2022
    Applicant: Siemens Aktiengesellschaft
    Inventors: Klaus Behringer, Wolfgang Feil, Peter Kaluza, Annemarie Lehmeier, Matthias Meier, Josef Burger, Thomas Bär
  • Patent number: 9387204
    Abstract: Compounds of formula (I) a tautomer or stereoisomer thereof, or a salt thereof, wherein ring B and the imidazole to which it is fused, R4, R6 and R7 have the meanings as given in the description and the claims, are effective inhibitors of the Pi3K/Akt pathway.
    Type: Grant
    Filed: November 26, 2013
    Date of Patent: July 12, 2016
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Swen Hölder, Armin Zülch, Thomas Bär, Thomas Maier, Astrid Zimmermann, Thomas Beckers, Volker Gekeler, Hemant Joshi, Yogesh Munot, Umesh Bhise, Sunil Chavan, Sachin Shivatare, Sarvesh Patel, Vikas Gore
  • Patent number: 8957064
    Abstract: Compounds of formula (I) or an N-oxide, a salt, a tautomer or a stereoisomer of said compound, or a salt of said N-oxide, tautomer or stereoisomer, wherein ring B and the pyrimidine to which it is fused, R4, R5, R6, R7, m and n have the meanings as given in the description and the claims, which are effective inhibitors of the Pi3K/Akt pathway, processes for their production and their use as pharmaceuticals.
    Type: Grant
    Filed: February 2, 2010
    Date of Patent: February 17, 2015
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Matthias Vennemann, Thomas Bär, Thomas Maier, Swen Hölder, Gerrit Beneke, Florian Dehmel, Armin Zülch, Andreas Strub, Stuart Ince, Hartmut Rehwinkel, Ningshu Liu, Ulf Bömer, Barbara Beckers
  • Patent number: 8815855
    Abstract: Compounds of a certain formula (I), in which R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in the description, are novel effective HDAC inhibitors.
    Type: Grant
    Filed: December 1, 2009
    Date of Patent: August 26, 2014
    Assignee: 4SC AG
    Inventors: Thomas Maier, Thomas Bär, Thomas Beckers, Astrid Zimmermann, Siegfried Schneider, Volker Gekeler
  • Publication number: 20140088110
    Abstract: Compounds of formula (I) a tautomer or stereoisomer thereof, or a salt thereof, wherein ring B and the imidazole to which it is fused, R4, R6 and R7 have the meanings as given in the description and the claims, are effective inhibitors of the Pi3K/Akt pathway.
    Type: Application
    Filed: November 26, 2013
    Publication date: March 27, 2014
    Applicant: BAYER INTELLECTUAL PROPERTY GmbH
    Inventors: Swen HÖLDER, Armin ZÜLCH, Thomas BÄR, Thomas MAIER, Astrid ZIMMERMANN, Thomas BECKERS, Volker GEKELER, Hemant JOSHI, Yogesh MUNOT, Umesh BHISE, Sunil CHAVAN, Sachin SHIVATARE, Sarvesh PATEL, Vikas GORE
  • Patent number: 8592591
    Abstract: Compounds of formula (I) a tautomer or stereoisomer thereof, or a salt thereof, wherein ring B and the imidazole to which it is fused, R4, R6 and R7 have the meanings as given in the description and the claims, are effective inhibitors of the Pi3K/Akt pathway.
    Type: Grant
    Filed: August 14, 2008
    Date of Patent: November 26, 2013
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Swen Hölder, Armin Zülch, Thomas Bär, Thomas Maier, Astrid Zimmermann, Thomas Beckers, Volker Gekeler, Hemant Joshi, Yogesh Munot, Umesh Bhise, Sunil Chavan, Sachin Shivatare, Sarvesh Patel, Vikas Gore
  • Patent number: 8530493
    Abstract: Compounds of a certain formula I, in which R1, R2, R3, R4, R5 and R6 have the meanings indicated in the description, are effective compounds with anti-proliferative and/or apoptosis inducing activity.
    Type: Grant
    Filed: February 21, 2007
    Date of Patent: September 10, 2013
    Assignee: 4SC AG
    Inventors: Matthias Vennemann, Thomas Bãr, Jürgen Braunger, Astrid Zimmermann, Volker Gekeler
  • Patent number: 8348558
    Abstract: The invention relates to a cutting insert having an essentially parallelepiped-shaped basic body with two larger spaced-apart longitudinal surfaces (10,11) which are connected to one another by two smaller transverse surfaces (12, 13) and two smaller longitudinal surfaces (14) designed as rake faces, wherein the smaller longitudinal surfaces (14) form with the adjacent surfaces a respective, encircling, closed cutting line which forms the cutting edges and rounded-off cutting corners, and the larger longitudinal surface (10, 11) merges on both sides via respective rounded-off edges into the smaller transverse surface (12, 13), and one of the rounded-off cutting corners is designed so as to project relative to a basic shape which is determined by the cutting lines, on both sides, of the larger longitudinal surfaces (10, 11) with the smaller longitudinal surfaces (14).
    Type: Grant
    Filed: August 22, 2006
    Date of Patent: January 8, 2013
    Assignee: Kennametal Widia Produktions GmbH & Co.KG
    Inventors: Jürgen Thomas Bär, Jochen Hecht
  • Patent number: 8232297
    Abstract: Compounds of a certain formula I, in which R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in the description, as well as salts thereof are novel effective HDAC inhibitors.
    Type: Grant
    Filed: September 8, 2006
    Date of Patent: July 31, 2012
    Assignee: 4SC AG
    Inventors: Thomas Maier, Thomas Beckers, Rolf-Peter Hummel, Martin Feth, Matthias Müller, Thomas Bär, Jürgen Volz
  • Patent number: 8188138
    Abstract: Compounds of a certain formula I, in which R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in the description, as well as salts thereof are novel effective HDAC inhibitors.
    Type: Grant
    Filed: September 8, 2006
    Date of Patent: May 29, 2012
    Assignee: 4SC AG
    Inventors: Thomas Maier, Thomas Beckers, Rolf-Peter Hummel, Martin Feth, Matthias Müller, Thomas Bär
  • Publication number: 20110065734
    Abstract: The present invention relates to a bifunctional compound of formula I or its pharmaceutically acceptable salts or solvates A-L-B (I) wherein A is a histone deacetylase (HDAC) inhibitory moiety, L is a single bond or a linker group and B is a protein kinase inhibitory moiety. The bifunctional compound according to formula (I) is useful for the treatment of malignant and non-malignant neoplasia and diseases related to abnormal cell growth.
    Type: Application
    Filed: November 14, 2008
    Publication date: March 17, 2011
    Applicant: 4SC AG
    Inventors: Thomas Bar, Thomas Maier, Thomas Beckers, Thomas Clossek, Siavosh Mahboobi, Andreas Sellmer
  • Publication number: 20100324038
    Abstract: The invention relates to compounds of formula I, wherein Ra is —C(O)OR1, in which R1 is 1-7C-alkyl, 3-7C-cycloalkyl, or 1-7C-alkyl substituted by one to four substituents independently selected from R2, Rb is -T-Q, in which T is 1-6C-alkylene or 3-7C-cycloalkylene, and either Q is optionally substituted by Rba and/or Rbb and/or Rbc, and is phenyl or naphthyl, or Q is optionally substituted by Rca and/or Rcb, and is Har, or Q is optionally substituted by Rda and/or Rdb, and is Het, or Q is optionally substituted by Rea and/or Reb, and is 3-7C-cycloalkyl, which are useful for the therapy of hyperproliferative diseases, in particular human cancer.
    Type: Application
    Filed: July 28, 2009
    Publication date: December 23, 2010
    Inventors: Klaus Pekari, Mathias Schmidt, Thomas Bär, Thomas Beckers, Björn Bartels
  • Publication number: 20100285149
    Abstract: Compounds of a certain formula I, in which Ra and Rb have the meanings indicated in the description, are novel effective compounds with anti-proliferative and apoptosis inducing activity.
    Type: Application
    Filed: August 15, 2007
    Publication date: November 11, 2010
    Inventors: Klaus Pekari, Mathias Schmidt, Astrid Zimmermann, Volker Gekeler, Thomas Beckers, Thomas Bär
  • Patent number: 7763728
    Abstract: Compounds of a certain formula (I) in which Ra and Rb have the meanings indicated in the description, are novel effective compounds with anti-proliferative and apoptosis inducing activity.
    Type: Grant
    Filed: May 24, 2006
    Date of Patent: July 27, 2010
    Assignee: 4SC AG
    Inventors: Klaus Pekari, Mathias Schmidt, Thomas Bär, Thomas Beckers, Petra Gimmnich
  • Patent number: 7741488
    Abstract: Compounds of a certain formula (I), in which Ra and Rb have the meanings indicated in the description, are novel effective compounds with anti-proliferative and apoptosis inducing activity.
    Type: Grant
    Filed: February 10, 2006
    Date of Patent: June 22, 2010
    Assignee: 4SC AG
    Inventors: Klaus Pekari, Mathias Schmidt, Thomas Bär, Thomas Beckers, Björn Bartels
  • Patent number: 7714136
    Abstract: Compounds of a certain formula (I) in which Ra and Rb have the meanings indicated in the description, are novel effective compounds with anti-proliferative and apoptosis inducing activity.
    Type: Grant
    Filed: May 24, 2006
    Date of Patent: May 11, 2010
    Assignee: 4SC AG
    Inventors: Klaus Pekari, Mathias Schmidt, Thomas Bär, Thomas Beckers, Petra Gimmnich
  • Patent number: 7714135
    Abstract: Compounds of a certain formula (I), in which Ra and Rb have the meanings indicated in the description, are novel effective compounds with anti-proliferative and apoptosis inducing activity.
    Type: Grant
    Filed: February 8, 2006
    Date of Patent: May 11, 2010
    Assignee: 4SC AG
    Inventors: Klaus Pekari, Mathias Schmidt, Thomas Bär, Thomas Beckers, Björn Bartels
  • Publication number: 20100104659
    Abstract: Compounds of a certain formula I, in which Ra, Rb and Rc have the meanings indicated in the description, are effective compounds with anti-proliferative and/or apoptosis inducing activity.
    Type: Application
    Filed: July 12, 2007
    Publication date: April 29, 2010
    Inventors: Matthias Vennemann, Thomas Bär, Thomas Maier, Andreas Lindenmaier, Jürgen Braunger, Markus Boehm, Astrid Zimmermann, Volker Gekeler
  • Publication number: 20100074862
    Abstract: Compounds of a certain formula (I), in which R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in the description, are novel effective HDAC inhibitors.
    Type: Application
    Filed: December 1, 2009
    Publication date: March 25, 2010
    Inventors: Thomas MAIER, Thomas BÄR, Thomas BECKERS, Astrid ZIMMERMANN, Siegfried SCHNEIDER, Volker GEKELER