Patents by Inventor Thomas Baranski

Thomas Baranski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20060010505
    Abstract: High throughput drug screening assay methods and related apparatus are described. Drosophila with screenably distinct characteristics are raised in multi-well microtiter plates on standard growth medium. Screenably distinct characteristics which mimic human cancer or cancer-related condition are established by modifying expression of an oncogene or tumor suppressor in the Drosophila. Compounds that putatively modify the screenably distinct characteristic are then tested by feeding the compounds to the Drosophila embryos, and determining whether the compound modifies the screenably distinct characteristic induced by modifying gene expression. The assay methods and related articles of composition can also be used to simultaneously assay toxicity of candidate compounds.
    Type: Application
    Filed: June 16, 2005
    Publication date: January 12, 2006
    Inventors: Thomas Baranski, Ross Cagan
  • Publication number: 20050260135
    Abstract: High throughput drug screening assay methods and related apparatus are described. Wild-type Drosophila are raised in multi-well microtiter plates on a growth medium having a high level of a sugar such as glucose. The high sugar diet during development induces screenably distinct characteristics in the wild-type Drosophila. Compounds that putatively modify the screenably distinct characteristic are tested by feeding to the Drosophila embryos, and determining whether the compound modifies the screenably distinct characteristic induced by the high sugar growth medium. The assay methods and related articles of composition can also be used to assay toxicity of candidate compounds.
    Type: Application
    Filed: January 14, 2005
    Publication date: November 24, 2005
    Inventors: Thomas Baranski, Ross Cagan