Patents by Inventor Thomas Becker

Thomas Becker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tetrahydropyridothiophenes for the treatment of proliferative diseases such as cancer
    Patent number: 7714135
    Abstract: Compounds of a certain formula (I), in which Ra and Rb have the meanings indicated in the description, are novel effective compounds with anti-proliferative and apoptosis inducing activity.
    Type: Grant
    Filed: February 8, 2006
    Date of Patent: May 11, 2010
    Assignee: 4SC AG
    Inventors: Klaus Pekari, Mathias Schmidt, Thomas Bär, Thomas Beckers, Björn Bartels
  • Compounds and use of tetrahydropyridothiophenes
    Patent number: 7714134
    Abstract: The compounds of a certain formula (1) in which Ra and Rb have the meanings indicated in the description are novel for treating hyperproliferative diseases and/or disorders responsive to the induction of apoptosis. The invention further relates to certain compounds of formula (I), in which Ra and Rb have the meanings indicated in the description.
    Type: Grant
    Filed: June 10, 2005
    Date of Patent: May 11, 2010
    Assignee: 4SC AG
    Inventors: Klaus Pekari, Thomas Baer, Mathias Schmidt, Thomas Beckers
  • Tetrahydropyridothiophenes
    Patent number: 7714136
    Abstract: Compounds of a certain formula (I) in which Ra and Rb have the meanings indicated in the description, are novel effective compounds with anti-proliferative and apoptosis inducing activity.
    Type: Grant
    Filed: May 24, 2006
    Date of Patent: May 11, 2010
    Assignee: 4SC AG
    Inventors: Klaus Pekari, Mathias Schmidt, Thomas Bär, Thomas Beckers, Petra Gimmnich
  • N-SULPHONYLPYRROLES AND THEIR USE AS HISTONE DEACETYLASE INHIBITORS
    Publication number: 20100074862
    Abstract: Compounds of a certain formula (I), in which R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in the description, are novel effective HDAC inhibitors.
    Type: Application
    Filed: December 1, 2009
    Publication date: March 25, 2010
    Inventors: Thomas MAIER, Thomas BÄR, Thomas BECKERS, Astrid ZIMMERMANN, Siegfried SCHNEIDER, Volker GEKELER
  • N-sulphonylpyrroles and their use as histone deacetylase inhibitors
    Patent number: 7666868
    Abstract: Compounds of a certain formula (I) in which R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in the description, are novel effective HDAC inhibitors.
    Type: Grant
    Filed: March 14, 2006
    Date of Patent: February 23, 2010
    Assignee: 4SC AG
    Inventors: Thomas Maier, Thomas Bär, Thomas Beckers, Astrid Zimmermann, Siegfried Schneider, Volker Gekeler
  • IDENTITY ENABLED DATA LEVEL ACCESS CONTROL
    Publication number: 20100030737
    Abstract: Mechanisms for identity enabled data level access control are provided. Data queries from principals are intercepted and access rights are assigned in response to identities associated with the principals. The access rights are enforced by modifying the queries and/or filtering results from the queries. The modified queries and/or filtered results are processed against a data store on behalf of the principals and returned to the principals.
    Type: Application
    Filed: July 29, 2008
    Publication date: February 4, 2010
    Inventors: Volker Gunnar Scheuber-Heinz, Lynn Crabb, Stephen R. Carter, David Kent Beus, Thomas Becker, Jed Rampton, Kevin Marinus Boogert, Michael William Cook
  • Sulphonylpyrrole Hydrochloride Salts as Histone Deacetylases Inhibitors
    Publication number: 20090297473
    Abstract: Compounds of a certain formula 1, in which R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in the description, as well as salts thereof are novel effective HDAC inhibitors.
    Type: Application
    Filed: September 8, 2006
    Publication date: December 3, 2009
    Applicant: Nycomed GmbH
    Inventors: Thomas Maier, Thomas Beckers, Rolf-Peter Hummel, Martin Feth, Matthias Müller, Thomas Bär
  • NOVEL TETRAHYDROPYRIDOTHIOPHENES
    Publication number: 20090270378
    Abstract: Compounds of a certain formula (I), in which Ra and Rb have the meanings indicated in the description, are novel effective compounds with anti-proliferative and/or apoptosis inducing activity.
    Type: Application
    Filed: March 26, 2009
    Publication date: October 29, 2009
    Applicant: NYCOMED GMBH
    Inventors: Klaus PEKARI, Thomas BAER, Bjoern BARTELS, Mathias SCHMIDT, Thomas BECKERS
  • Novel Sulphonylpyrroles as Inhibitors of Hdac S Novel Sulphonylpyrroles
    Publication number: 20090263353
    Abstract: Compounds of a certain formula I, in which R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in the description, as well as salts thereof are novel effective HDAC inhibitors.
    Type: Application
    Filed: September 8, 2006
    Publication date: October 22, 2009
    Applicant: Nycomed GmbH
    Inventors: Thomas Maier, Thomas Beckers, Rolf-Peter Hummel, Martin Feth, Matthias Muller, Thomas Bar, Jurgen Volz
  • Novel tetrahydropyridothiophenes
    Publication number: 20090258873
    Abstract: Compounds of a certain formula (I), in which Ra and Rb have the meanings indicated in the description, are novel effective compounds with anti-proliferative and apoptosis inducing activity.
    Type: Application
    Filed: March 26, 2009
    Publication date: October 15, 2009
    Inventors: Klaus PEKARI, Mathias SCHMIDT, Thomas BAR, Thomas BECKERS, Petra GIMMNICH
  • NOVEL TETRAHYDROPYRIDOTHIOPHENES
    Publication number: 20090257977
    Abstract: Compounds of a certain formula (I), in which Ra and Rb have the meanings indicated in the description, are novel effective compounds with anti-proliferative and apoptosis inducing activity.
    Type: Application
    Filed: March 27, 2009
    Publication date: October 15, 2009
    Inventors: Klaus Pekari, Mathias Schmidt, Thomas Bar, Thomas Beckers, Petra Gimmnich
  • Tetrahydropyridothiophenes As Antripoliferative Agents For The Treatment Of Cancer
    Publication number: 20090252706
    Abstract: The invention relates to compounds of formula (I) wherein Ra is —C(O)ORI, in which R1 is 1-7C-alkyl. 3-7C-cycloakyl, 1-7C-alkyl substituted by Raa, or 2-7C-alkyl substituted by Rab and Rac on different carbon atoms, Rb is -T-Q, in which T is 1-6C-alkylene or 3-7C-cycloalkylene, and Q is substituted by Rba and Rbb and Rbc, and is phenyl, which are useful for the therapy of hyperproliferative diseases, in particular human cancer.
    Type: Application
    Filed: March 25, 2009
    Publication date: October 8, 2009
    Inventors: Klaus Pekari, Mathias Schmidt, Thomas Bar, Thomas Beckers, Bjorn Bartels
  • Method for transmitting notification messages on submitting multimedia messages to telecommunications devices embodied as multimedia message sinks
    Patent number: 7590410
    Abstract: A method is provided for transmitting notification messages for submission of multimedia messages to telecommunications devices embodied as multimedia message sinks, wherein to reduce the effort involved in transmitting notification messages and the associated administration effort in an entity sending the notification message on submission of multimedia messages to telecommunications devices embodied as multimedia message sinks independently of their multimedia capabilities, a service center responsible for sending the notification messages transmits on submission of multimedia messages in a notification message a first notification information which is preferably binary coded, and a second notification information which is preferably embodied as text information, uniformly to different variants of telecommunications devices as regards their multimedia capabilities.
    Type: Grant
    Filed: March 12, 2004
    Date of Patent: September 15, 2009
    Assignee: Siemens Aktiengesellschaft
    Inventors: Thomas Becker, Jan-Christoph Geiger, Werner Goertz, Guido Heling, Peter Mros, Stefan Nieder, Albert Ratermann, Stanislaus Willemsen, Marco van de Logt
  • TETRAHYDROPYRIDOTHIOPHENES FOR THE TREATMENT OF PROLIFERATIVE DISEASES SUCH AS CANCER
    Publication number: 20090227577
    Abstract: The invention relates to compounds of formula I, wherein Ra is —C(O)ORI, in which R1 is 1-7C-alkyl, 3-7C-cycloalkyl, or 1-7C-alkyl substituted by one to four substituents independently selected from R2, Rb is -T-Q, in which T is 1-6C-alkylene or 3-7C-cycloalkylene, and either Q is optionally substituted by Rba and/or Rbb and/or Rbc, and is phenyl or naphthyl, or Q is optionally substituted by Rca and/or Rcb, and is Has, or Q is optionally substituted by Rda and/or Rdb, and is Het, or Q is optionally substituted by Rea and/or Reb, and is 3-7C-cycloalkyl, which are useful for the therapy of hyperproliferative diseases, in particular human cancer.
    Type: Application
    Filed: March 26, 2009
    Publication date: September 10, 2009
    Inventors: Klaus PEKARI, Mathias Schmidt, Thomas Bar, Thomas Beckers, Bjorn Bartels
  • NOVEL COMPOUNDS AND USE OF TETRAHYDROPYRIDOPYRIDOTHIOPHENES
    Publication number: 20090209534
    Abstract: The use of tetrahydropyridothiophenes of a certain formula (I), in which Ra and Rb have the meanings indicated in the description, is novel for treating hyperproliferative diseases and/or disorders responsive to the induction of apoptosis.
    Type: Application
    Filed: March 27, 2009
    Publication date: August 20, 2009
    Inventors: Klaus PEKARI, Thomas Baer, Mathias Schmidt, Thomas Beckers
  • COMPOSITIONS AND PROCESSES FOR IMPROVED MASS SPECTROMETRY ANALYSIS
    Publication number: 20090181376
    Abstract: The invention provides a novel additive for improved analysis by mass spectrometry. More specifically, ascorbic acid has been found to reduce or eliminate the presence of adducts commonly present in mass spectra. The improved processes and compositions of the invention allow for increased accuracy, sensitivity and throughput for samples analyzed by mass spectrometry.
    Type: Application
    Filed: January 15, 2008
    Publication date: July 16, 2009
    Applicant: SEQUENOM, INC.
    Inventor: Thomas Becker
  • Tetrahydropyridothiophenes For Use In The Treatment Of Cancer
    Publication number: 20090163538
    Abstract: Compounds of formula (I), in which Ra and Rb have the meanings indicated in the description, are novel effective compounds with anti-proliferative and/or apoptosis inducing activity.
    Type: Application
    Filed: February 23, 2009
    Publication date: June 25, 2009
    Inventors: Klaus PEKARI, Thomas BAER, Mathias SCHMIDT, Thomas BECKERS
  • FUSED BICYCLIC IMIDAZOLES
    Publication number: 20090156604
    Abstract: Compounds of formula (I) a tautomer or stereoisomer thereof, or a salt thereof, wherein ring B and the imidazole to which it is fused, R4, R6 and R7 have the meanings as given in the description and the claims, are effective inhibitors of the Pi3K/Akt pathway.
    Type: Application
    Filed: August 14, 2008
    Publication date: June 18, 2009
    Inventors: Swen HOLDER, Armin Zulch, Thomas Bar, Thomas Maier, Astrid Zimmermann, Thomas Beckers, Volker Gekeler, Hemant Joshi, Yogesh Munot, Umesh Bhise, Sunil Chavan, Sachin Shivatare, Sarvesh Patel, Vikas Gore
  • FUSED BICYCLIC PYRIMIDINES
    Publication number: 20090137607
    Abstract: Compounds of formula (I) a tautomer or stereoisomer thereof, or a salt thereof, wherein ring B and the pyrimidine to which it is fused, R4, R5, R6 and R7 have the meanings as given in the description and the claims, are effective inhibitors of the Pi3K/Akt pathway.
    Type: Application
    Filed: August 14, 2008
    Publication date: May 28, 2009
    Inventors: Swen Holder, Matthias Vennemann, Gerrit Beneke, Armin Zulch, Volker Gekeler, Thomas Beckers, Astrid Zimmermann, Hemant Joshi
  • Sulfonylpyrroles as Histone Deacetylase Inhibitors
    Publication number: 20090117074
    Abstract: The invention relates to compounds of formula (I) which are effective inhibitors of histone deacetylases.
    Type: Application
    Filed: April 7, 2006
    Publication date: May 7, 2009
    Applicant: NYCOMED GmbH
    Inventors: Thomas Maier, Thomas Bar, Thomas Beckers, Astrid Zimmermann, Frank Dullweber, Volker Gekeler