Patents by Inventor Thomas Berthelot
Thomas Berthelot has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220053766Abstract: A process for preparing a biocidal, bactericidal and/or bacteriostatic material including the preparation of a polymer precursor solution that has (a) at least one monomer A having a porphyrin group and at least one radical polymerizable function, (b) at least one radical polymerizable monomer B, a photoinitiator, and (c) at least one of the monomers chosen from a monomer C having a quaternary amine and a radical polymerizable function; and/or a monomer D having copper and a radical polymerizable function. Also, the material obtainable by the process and its uses.Type: ApplicationFiled: December 19, 2019Publication date: February 24, 2022Applicants: COMMISSARIAT À L'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES (CEA), CONSERVATOIRE NATIONAL DES ARTS ET METIERS (CNAM), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS).Inventors: Thomas BERTHELOT, Céline GOULARD-HUET, Fanny HAUQUIER
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Patent number: 11167487Abstract: A deposition system including: a container arranged to contain material to be deposited and including an inlet and an outlet, a pneumatic system arranged to inject, through the entrance, gas in the container, so this gas exerts pressure on the material to be deposited. The deposition system including a controller of the pneumatic system arranged to control at least one injection, through the inlet, of gas at an adjusting pressure, so that a convex meniscus of material to be deposited protrudes from the outlet of the container, then at least one gas' injection, through the inlet, respectively at least a deposition pressure greater than the adjusting pressure, so that the material to be deposited flows out of the container by its outlet.Type: GrantFiled: May 16, 2019Date of Patent: November 9, 2021Assignee: KELENN TECHNOLOGYInventors: Thomas Berthelot, Didier Rousseau
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Patent number: 11014121Abstract: The invention relates to a method for functionalising a surface of a solid substrate with at least one acrylic acid polymer layer, said method including the steps of: i) placing the surface in contact with a solution having of at least one acrylic acid homopolymer, a solvent and, optionally, metal salts; ii) removing the solvent from the solution in contact with the surface; and iii) binding the polymer to the surface by thermal treatment.Type: GrantFiled: April 3, 2015Date of Patent: May 25, 2021Assignee: Commissariat A L'Energie Atomique Et Aux Energies AlternativesInventors: Pascal Viel, Thomas Berthelot, Xavier Lefevre, Jérôme Polesel Maris
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Patent number: 11009573Abstract: A liquid-state nuclear-magnetic-resonance measurement cell includes a reservoir for a liquid medium; a fluidic circuit connected to the reservoir and comprising a measurement chamber; a gas injector opening into the fluidic circuit, at a distance from the measurement chamber; and a coil encircling the measurement chamber; wherein it also comprises at least one capacitive element forming, with the coil, an electromagnetic resonator; and in that it has a shape allowing its introduction into a nuclear-magnetic-resonance probe in replacement of an assembly formed by a nuclear-magnetic-resonance tube and a spinner bearing the tube, the coil encircling the measurement chamber being then positioned so as to couple by induction to at least one radiofrequency coil of the probe. Nuclear-magnetic-resonance measurement system comprising such a measurement cell. Magnetic-resonance measurement method using such a cell is also provided.Type: GrantFiled: March 8, 2018Date of Patent: May 18, 2021Assignee: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVESInventors: Guillaume Carret, Thomas Berthelot, Patrick Berthault
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Publication number: 20210069971Abstract: A deposition system including: a container arranged to contain material to be deposited and including an inlet and an outlet, a pneumatic system arranged to inject, through the entrance, gas in the container, so this gas exerts pressure on the material to be deposited. The deposition system including a controller of the pneumatic system arranged to control at least one injection, through the inlet, of gas at an adjusting pressure, so that a convex meniscus of material to be deposited protrudes from the outlet of the container, then at least one gas' injection, through the inlet, respectively at least a deposition pressure greater than the adjusting pressure, so that the material to be deposited flows out of the container by its outlet.Type: ApplicationFiled: May 16, 2019Publication date: March 11, 2021Inventors: Thomas BERTHELOT, Didier ROUSSEAU
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Publication number: 20200033427Abstract: A liquid-state nuclear-magnetic-resonance measurement cell includes a reservoir for a liquid medium; a fluidic circuit connected to the reservoir and comprising a measurement chamber; a gas injector opening into the fluidic circuit, at a distance from the measurement chamber; and a coil encircling the measurement chamber; wherein it also comprises at least one capacitive element forming, with the coil, an electromagnetic resonator; and in that it has a shape allowing its introduction into a nuclear-magnetic-resonance probe in replacement of an assembly formed by a nuclear-magnetic-resonance tube and a spinner bearing the tube, the coil encircling the measurement chamber being then positioned so as to couple by induction to at least one radiofrequency coil of the probe. Nuclear-magnetic-resonance measurement system comprising such a measurement cell. Magnetic-resonance measurement method using such a cell is also provided.Type: ApplicationFiled: March 8, 2018Publication date: January 30, 2020Inventors: Guillaume CARRET, Thomas BERTHELOT, Patrick BERTHAULT
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Patent number: 10428435Abstract: The present invention relates to a method for modifying the surface of a substrate made of electrically conductive metal oxide and notably made of ITO, comprising the following steps consisting in: (i) bringing into contact said surface with a solution containing copper ions (Cu2+) and ammonia then washing and optionally drying the surface thus obtained; and (ii) bringing into contact the surface obtained following step (i) with a solution containing sodium tetraborohydride then washing and optionally drying the surface of said conductive metal oxide substrate. The present invention relates to the use of such a method within the scope of the metallization by copper of a conductive metal oxide substrate as well as the surfaces of a modified and metallized conductive metal oxide substrate thus obtained.Type: GrantFiled: April 14, 2017Date of Patent: October 1, 2019Assignee: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVESInventors: Yoan Bourlier, Thomas Berthelot
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Patent number: 10365236Abstract: There is provided a Nuclear Magnetic Resonance (NMR) measurement cell for use with a solution enabling the introduction of a gas into said solution. The measurement cell includes at least a detection volume designed to be installed in a static magnetic field of an NMR spectrometer, and includes in said detection volume, a gas introduction zone, a measurement chamber for the solution at a distance from the gas introduction zone and a network of conduits for the solution formed to set up fluid communication between the gas introduction zone and the measurement chamber. The gas introduction zone includes at least one gas inlet in the network of conduits, to generate bubbles in the gas introduction zone only. There is also provided a method of manufacturing such a measurement cell and a measurement assembly including such a measurement cell.Type: GrantFiled: December 16, 2015Date of Patent: July 30, 2019Assignee: Comissariat a l'energie atomique et aux energies alternativesInventors: Alexandre Causier, Patrick Berthault, Thomas Berthelot, Guillaume Carret
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Patent number: 10272157Abstract: A process for preparing a porous solid with an outer surface modified by at least one polymer; the polymer being simultaneously synthetized in solution and grafted on the outer surface of the solid, includes contacting: a porous solid; and a polymer-precursor solution comprising an adhesion primer, and at least one polymerizable monomer; under conditions enabling the formation of radical entities.Type: GrantFiled: October 8, 2015Date of Patent: April 30, 2019Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (CEA), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE VERSAILLES SAINT-QUENTIN-EN-YVELINES, UNIVERSITE PARIS-SUD 11Inventors: Thomas Berthelot, Elena Bellido Vera, Ruxandra Gref, Patricia Horcajada Cortes, Christian Serre, Patrick Couvreur
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Patent number: 9890235Abstract: A method is provided for preparing an organic film on the surface of a solid support including the steps of (a) applying, to the surface, by transfer or by spraying, a solution containing at least one cleavable aryl salt; and (b) subjecting the solution to a UV or visible irradiation, such that irradiation radical entities are formed from the cleavable aryl salt and an organic film is grafted. Further provided is a kit of elements for the implementation of such a method.Type: GrantFiled: March 21, 2012Date of Patent: February 13, 2018Assignee: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVESInventors: Thomas Berthelot, Pascal Viel, Alexandre Garcia, Bruno Jousselme, Cecile Baudin
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Patent number: 9835576Abstract: A method of manufacturing a biosensor having a microbeam linked to a support, at least one electrode a biological molecule A grafted onto the microbeam in a different zone from the zone where the electrode is embedded, and a mechanoelectrical transducer for converting variations of the mechanical properties of the microbeam into an electrical signal, when the biological molecule A is placed in contact with a biological molecule B to be detected and/or quantified. The method includes: formation of an electrode on fluoropolymer material sheet, passivation of the electrode(s), creation of the form of the biosensor in the sheet of polymer material and separation of this form from the sheet, functionalization either of a prefunctionalized zone or of a zone of the microbeam, this zone being different from the zone wherein the electrode is embedded, and grafting of a biological molecule A onto the functionalized zone.Type: GrantFiled: February 14, 2012Date of Patent: December 5, 2017Assignee: Commissariat A L'Energie Atomique Et Aux Energies AlternativesInventors: Jérôme Polesel Maris, Thomas Berthelot
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Publication number: 20170298525Abstract: The present invention relates to a method for modifying the surface of a substrate made of electrically conductive metal oxide and notably made of ITO, comprising the following steps consisting in: (i) bringing into contact said surface with a solution containing copper ions (Cu2+) and ammonia then washing and optionally drying the surface thus obtained; and (ii) bringing into contact the surface obtained following step (i) with a solution containing sodium tetraborohydride then washing and optionally drying the surface of said conductive metal oxide substrate. The present invention relates to the use of such a method within the scope of the metallisation by copper of a conductive metal oxide substrate as well as the surfaces of a modified and metallised conductive metal oxide substrate thus obtained.Type: ApplicationFiled: April 14, 2017Publication date: October 19, 2017Applicant: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVESInventors: Yoan BOURLIER, Thomas Berthelot
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Patent number: 9725602Abstract: This invention relates to a method for preparing an organic film at the surface of a solid support, with a step of contacting said surface with a liquid solution including (i) at least one solvent, (ii) at least one adhesion primer, under non-electrochemical conditions, and allowing the formation of radical entities based on the adhesion primer. The liquid solution can also include (iii) at least one monomer different from the adhesion primer and radically polymerizable. This invention also relates to a non-electrically-conductive solid support on which an organic film according to said method is grafted, and a kit for preparing an essentially polymeric organic film at the surface of a solid support.Type: GrantFiled: December 19, 2007Date of Patent: August 8, 2017Assignee: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVESInventors: Vincent Mevellec, Sebastien Roussel, Serge Palacin, Guy Deniau, Thomas Berthelot, Cecile Baudin, Adhitya Trenggono
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Publication number: 20170113249Abstract: The invention relates to a method for functionalising a surface of a solid substrate with at least one acrylic acid polymer layer, said method including the steps of: i) placing the surface in contact with a solution having of at least one acrylic acid homopolymer, a solvent and, optionally, metal salts; ii) removing the solvent from the solution in contact with the surface; and iii) binding the polymer to the surface by thermal treatment.Type: ApplicationFiled: April 3, 2015Publication date: April 27, 2017Inventors: Pascal Viel, Thomas Berthelot, Xavier Lefevre, Jérôme Polesel Maris
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Publication number: 20170102380Abstract: The immobilization of biomolecules on a non-functionalized carrier by irradiating the biomolecule-impregnated carrier with a light of a wavelength of at least 340 nm.Type: ApplicationFiled: March 5, 2015Publication date: April 13, 2017Inventors: Julie CREDOU, Thomas BERTHELOT, Rita FADDOUL
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Patent number: 9453284Abstract: The present invention relates to a process for chemically modifying, within its thickness, a polymer matrix chosen from matrices made of fluoropolymers and matrices made of aliphatic polymers, said process comprising at least one step consisting in irradiating said matrix with UV light having a wavelength of less than 300 nm in order to generate, within the thickness of said matrix, zones that have short polymer chains, formed by scission of the existing chains during the passage of the UV radiation and that have free radicals denoted hereinbelow as “activated zones”. The present invention also relates to the polymer matrix capable of being chemically modified by such a process.Type: GrantFiled: April 30, 2010Date of Patent: September 27, 2016Assignee: Commissariat a L'Energie Atomique et aux Energies AlternativesInventors: Thomas Berthelot, Cécile Baudin
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Publication number: 20160178544Abstract: There is provided a Nuclear Magnetic Resonance (NMR) measurement cell for use with a solution enabling the introduction of a gas into said solution. he measurement cell includes at least a detection volume designed to be installed in a static magnetic field of an NMR spectrometer, and includes in said detection volume, a gas introduction zone, a measurement chamber for the solution at a distance from the gas introduction zone and a network of conduits for the solution formed to set up fluid communication between the gas introduction zone and the measurement chamber. The gas introduction zone includes at least one gas inlet in the network of conduits, to generate bubbles in the gas introduction zone only. There is also provided a method of manufacturing such a measurement cell and a measurement assembly including such a measurement cell.Type: ApplicationFiled: December 16, 2015Publication date: June 23, 2016Applicant: Commissariat A L'Energie Atomique et aux Energies AlternativesInventors: Alexandre CAUSIER, Patrick BERTHAULT, Thomas BERTHELOT, Guillaume CARRET
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Publication number: 20160101192Abstract: A process for preparing a porous solid with an outer surface modified by at least one polymer; the polymer being simultaneously synthetized in solution and grafted on the outer surface of the solid, includes contacting: a porous solid; and a polymer-precursor solution comprising an adhesion primer, and at least one polymerizable monomer; under conditions enabling the formation of radical entities.Type: ApplicationFiled: October 8, 2015Publication date: April 14, 2016Inventors: Thomas BERTHELOT, Elena BELLIDO VERA, Ruxandra GREF, Patricia HORCAJADA CORTES, Christian SERRE, Patrick COUVREUR
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Patent number: 9139862Abstract: The invention pertains to a cyclic peptide comprising the following sequence: -S1-X1-S2-X2- wherein S1 is a first target peptide sequence of a protease enzyme E1, S2 is a second target peptide sequence of a protease enzyme E2, S1 and S2 possibly being the same or different, said first peptide sequence S1 and said second peptide sequence S2 comprising 4 to 14 amino acids, E1 and E2 possibly corresponding to the same protease enzyme or to two different protease enzymes, X1 is a probe carrying a fluorescent donor group and X2 is a probe carrying a fluorescent or non-fluorescent acceptor group. Application of these peptides to determination of the activity of protease enzymes.Type: GrantFiled: June 10, 2009Date of Patent: September 22, 2015Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, UNIVERSITE VICTOR SEGALEN-BORDEAUX 2Inventors: Thomas Berthelot, Gérard Deleris
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Patent number: 9085715Abstract: The present invention relates to a process for assembling at least one zone of a first surface with at least one zone of a second surface or with a molecule of interest, comprising a step that consists in placing the said zone of the said first surface in contact with the said zone of the said second surface or with the said molecule of interest, the said zone of the said first surface bearing at least one radical and/or ionic species. The present invention also relates to a solid support whose surface bears at least one zone with at least one radical and/or ionic species, with at least one adhesion primer, or with at least one adhesion primer precursor, and to its various uses.Type: GrantFiled: April 2, 2009Date of Patent: July 21, 2015Assignee: COMMISSARIAT A L'ENERGIE ATOMIQUEInventors: Thomas Berthelot, Guy Deniau, Vincent Huc, Xuan Tuan Le, Fabien Nekelson, Sébastien Roussel, Pascal Viel