Patents by Inventor Thomas Blue
Thomas Blue has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240131144Abstract: The present invention relates to formulations of dengue virus vaccine comprising at least one live, attenuated dengue virus or live, attenuated chimeric flavivirus, a buffer, a sugar, a cellulose derivative, a glycol or sugar alcohol, optionally an alkali or alkaline salt and an amino acid; and formulations of dengue virus vaccine comprising at least one live, attenuated dengue virus or live, attenuated chimeric flavivirus, a buffer, a sugar of at least 150 mg/ml, a carrier, and optionally an alkali or alkaline salt and an amino acid.Type: ApplicationFiled: December 6, 2023Publication date: April 25, 2024Applicant: Merck Sharp & Dohme LLCInventors: Michael S. Ryan, Sherrie-Ann P. Martin, Morrisa Jones, Justin Stanbro, Akhilesh Bhambhani, Jeffrey Thomas Blue, Heidi Joanne Pixley, Erin J. Green-Trexler, Lynne Ann Isopi
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Patent number: 11957921Abstract: Disclosed herein is a delivery system for delivering a leadless pacemaker. The delivery system may include a catheter, which may be a guide catheter. The catheter includes a distal end, a proximal end opposite the distal end, a lumen extending between the distal end and the proximal end, and a locking hub operably coupled to the proximal end. The locking hub includes a lumen segment of the lumen. In one implementation, self-biasing of the lumen segment places the lumen segment out of alignment with a rest of the lumen. Deflecting the lumen segment against the self-biasing of the lumen segment places the lumen segment in coaxial alignment with the rest of the lumen. In another implementation, self-biasing of the lumen segment reduces an inner diameter of the lumen segment and actuation of the locking hub expands the inner diameter.Type: GrantFiled: January 27, 2021Date of Patent: April 16, 2024Assignee: PACESETTER, INC.Inventors: Brett Hillukka, Thomas B. Eby, Christopher Alan Hubbard, Bernhard Arnar, Bradley Knippel, Jeremiah Blue, Jennifer Heisel, Rebecca Stufft, Adam Weber
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Patent number: 11883480Abstract: The present invention relates to formulations of dengue virus vaccine comprising at least one live, attenuated dengue virus or live, attenuated chimeric flavivirus, a buffer, a sugar, a cellulose derivative, a glycol or sugar alcohol, optionally an alkali or alkaline salt and an amino acid; and formulations of dengue virus vaccine comprising at least one live, attenuated dengue virus or live, attenuated chimeric flavivirus, a buffer, a sugar of at least 150 mg/ml, a carrier, and optionally an alkali or alkaline salt and an amino acid.Type: GrantFiled: July 26, 2022Date of Patent: January 30, 2024Assignee: Merck Sharp & Dohme LLCInventors: Michael S. Ryan, Sherrie-Ann P. Martin, Jeffrey Thomas Blue, Heidi Joanne Pixley, Erin J. Green-Trexler, Lynne Ann Isopi
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Publication number: 20230277654Abstract: The present invention relates to stable formulations of a cytomegalovirus (CMV) comprising for example, a genetically modified CMV that is conditionally replication defective, a buffer, alkali or alkaline salt, a sugar, a cellulose derivative and optionally a polyol.Type: ApplicationFiled: November 30, 2022Publication date: September 7, 2023Applicant: Merck Sharp & Dohme LLCInventors: Muneeswara Babu Medi, Harrison Bradford Davis, Lorenzo H. Chen, Lynne Ann Isopi, Jeffrey Thomas Blue, Heidi Joanne Pixley, Erin J. Green-Trexler
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Publication number: 20230061673Abstract: The present invention relates to formulations of dengue virus vaccine comprising at least one live, attenuated dengue virus or live, attenuated chimeric flavivirus, a buffer, a sugar, a cellulose derivative, a glycol or sugar alcohol, optionally an alkali or alkaline salt and an amino acid; and formulations of dengue virus vaccine comprising at least one live, attenuated dengue virus or live, attenuated chimeric flavivirus, a buffer, a sugar of at least 150 mg/ml, a carrier, and optionally an alkali or alkaline salt and an amino acid.Type: ApplicationFiled: July 26, 2022Publication date: March 2, 2023Applicant: Merck Sharp & Dohme LLCInventors: Michael S. Ryan, Sherrie-Ann P. Martin, Morrisa Jones, Justin Stanbro, Akhilesh Bhambhani, Jeffrey Thomas Blue, Heidi Joanne Pixley, Erin J. Green-Trexler, Lynne Ann Isopi
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Publication number: 20220105169Abstract: The present invention provides polysaccharide-protein conjugate vaccine formulations comprising a buffer, surfactant, sugar, alkali or alkaline salt, aluminum adjuvant, optionally a bulking agent, and optionally a polymer.Type: ApplicationFiled: December 17, 2021Publication date: April 7, 2022Applicant: Merck Sharp & Dohme Corp.Inventors: Ramesh V. Chintala, Akhilesh Bhambhani, Christopher David Mensch, Denise K. Nawrocki, Jeffrey Thomas Blue
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Publication number: 20210299247Abstract: The present invention relates to stable formulations of a cytomegalovirus (CMV) comprising for example, a genetically modified CMV that is conditionally replication defective, a buffer, alkali or alkaline salt, a sugar, a cellulose derivative and optionally a polyol.Type: ApplicationFiled: October 29, 2018Publication date: September 30, 2021Applicant: Merck Sharp & Dohme Corp.Inventors: Muneeswara Babu Medi, Harrison Bradford Davis, Lorenzo H. Chen, Lynne Ann Isopi, Jeffrey Thomas Blue, Heidi Joanne Pixley, Erin J. Green-Trexler
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Publication number: 20200390877Abstract: The present invention relates to formulations of dengue virus vaccine comprising at least one live attenuated dengue virus or live attenuated chimeric flavivirus, a buffer, a sugar, a cellulose derivative, a glycol or sugar alcohol, optionally an alkali or alkaline salt and an amino acid; and formulations of dengue virus vaccine comprising at least one live attenuated dengue virus or live attenuated chimeric flavivirus, a buffer, a sugar of at least 150 mg/ml, a carrier, and optionally an alkali or alkaline salt and an amino acid.Type: ApplicationFiled: December 3, 2018Publication date: December 17, 2020Applicant: Merck Sharp & Dohme Corp.Inventors: Michael S. Ryan, Sherrie-Ann P. Martin, Morrisa Jones, Justin Stanbro, Akhilesh Bhambhani, Jeffrey Thomas Blue, Heidi Joanne Pixley, Erin J. Green-Trexler, Lynne Ann Isopi
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Publication number: 20200360500Abstract: The present invention provides polysaccharide-protein conjugate vaccine formulations comprising a buffer, surfactant, sugar, alkali or alkaline salt, aluminum adjuvant, optionally a bulking agent, and optionally a polymer.Type: ApplicationFiled: August 13, 2018Publication date: November 19, 2020Applicant: Merck Sharp & Dohme Corp.Inventors: Ramesh V. Chintala, Akhilesh Bhambhani, Christopher David Mensch, Denise K. Nawrocki, Jeffrey Thomas Blue
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Publication number: 20150001798Abstract: A strategy card game where multiple players use point and action cards paid for by dice rolls in order to accumulate a specified point total. The embodiment incompasses buff/debuff cards to facilitate the strategy aspect of game play with each player taking turns in sequence until one player reaches a predetermined point total and is declared the winner.Type: ApplicationFiled: July 1, 2013Publication date: January 1, 2015Inventor: Thomas Blue
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Patent number: 7195617Abstract: A collection device for collecting material during a surgical procedure includes a collection chamber defined by an encompassing wall and having an opening sufficient for permitting collection of the material during the surgical procedure. A wicking material is positioned outside the collection chamber and is in fluid association therewith sufficient to wick fluid from within the collection chamber. The device also includes a scoop wall extending from the collection chamber and having a distal end portion for positioning proximate a source of the material and for guiding the material to the collection chamber wherein the scoop wall includes curved sidewall portions that are separated from the encompassing wall such that the scoop wall is bendable with respect to the chamber.Type: GrantFiled: March 3, 2004Date of Patent: March 27, 2007Assignee: Six-O, Ltd.Inventors: Lew Papendick, Thomas Blue
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Publication number: 20050197638Abstract: A collection device for collecting material during a surgical procedure includes a collection chamber defined by an encompassing wall and having an opening sufficient for permitting collection of the material during the surgical procedure. A wicking material is positioned outside the collection chamber and is in fluid association therewith sufficient to wick fluid from within the collection chamber. The device also includes a scoop wall extending from the collection chamber and having a distal end portion for positioning proximate a source of the material and for guiding the material to the collection chamber wherein the scoop wall includes curved sidewall portions that are separated from the encompassing wall such that the scoop wall is bendable with respect to the chamber.Type: ApplicationFiled: March 3, 2004Publication date: September 8, 2005Applicant: Six-O, Ltd.Inventors: Lew Papendick, Thomas Blue
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Publication number: 20040167529Abstract: The present invention includes a collection device for collecting material during a surgical procedure. In one aspect, the collection device includes a collection chamber having an opening sufficient for permitting collection of the material during the surgical procedure and a scoop wall extending from the encompassing wall, the scoop wall having a distal end portion for positioning proximate a source of the material and for guiding the material to the collection chamber. In another aspect of the invention, the collection chamber has at least one aperture within the collection chamber of a size to permit flow of fluid from the chamber when the collected material is contained within the chamber. Fluid may also be poured out of the chamber without the collected material following the fluid thereby retaining the collected material within the chamber.Type: ApplicationFiled: March 27, 2003Publication date: August 26, 2004Applicant: Six-O, Ltd.Inventors: Lew Papendick, Thomas Blue