Abstract: A bone cement pressuriser (50) comprising a pressuriser head. The pressuriser head has a first side (51) coupled to or configured to couple to an end of a pressuriser handle and a second side (52) configured to transfer pressure to bone cement in a bone cavity. The second side of the pressuriser head is defined by a first, convex curved surface (53) and a second surface (54) forming a ring surrounding the first surface and extending radially beyond the first surface. A method of pressurising bone cement using the bone cement pressuriser is also disclosed. The first surface is configured to pressurise bone cement within a bone cavity and the second surface is configured to both pressurise bone cement within the bone cavity and to seal about the periphery of the bone cavity.

Abstract: A system and method for processing mammographic images of target breast tissue is provided. The mammographic images are processed to generate modified images. A deep learning algorithm, having a tailored Convolutional Neural Networks (CNN) model, is applied to the modified images to generate a first output and a second output. Global features associated with the entirety of the mammographic images are extracted by using the first output. Local features associated with Regions of Interest (ROIs) of the mammographic images are extracted by using the second output. The global features and the local features are combined and fuse to generate an indicator representative of likelihood of malignancy of the target breast tissue.

Abstract: A system and method for processing mammographic images of target breast tissue is provided. The mammographic images are processed to generate modified images. A deep learning algorithm, having a tailored Convolutional Neural Networks (CNN) model, is applied to the modified images to generate a first output and a second output. Global features associated with the entirety of the mammographic images are extracted by using the first output. Local features associated with Regions of Interest (ROIs) of the mammographic images are extracted by using the second output. The global features and the local features are combined and fuse to generate an indicator representative of likelihood of malignancy of the target breast tissue.

Abstract: A missile, such as a cruise missile, has a nose payload portion having a frangible nose cover and a relatively hard target penetration nose cone. The nose cone may have a liquid fuel tank within, and a chemical energy explosive charge, such as a shaped charge, aft of the liquid fuel tank. The target penetration nose cone enables perforation of certain types of targets prior to detonation of the chemical energy explosive and the liquid fuel. The frangible nose cover is configured to be easily perforated or otherwise removed by the explosive force of the chemical energy explosive charge when the missile system is utilized for the attack of hard targets. The nose payload portion may have a fragmentation case, with one or more features designed to enhance fragmentation during detonation of the explosive and/or the liquid fuel.