Patents by Inventor Thomas Bourgeron

Thomas Bourgeron has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polynucleotide and protein involved in synaptogenesis, variants thereof, and their therapeutic and diagnostic uses
    Patent number: 7906640
    Abstract: The invention relates to a kit for diagnosing autism linked to a mutation in a protein belonging to the family of human neuroligins.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: March 15, 2011
    Assignees: Institut National de la Sante Et de la Recherche Medicale (INSERM), Institut Pasteur, Assistance Publique-Hopitaux de Paris
    Inventors: Thomas Bourgeron, Stephane Jamain, Helene Quach, Catalina Betancur, Marion Leboyer, Christopher Gillberg
  • Genetic variations associated with psychiatric disorders
    Publication number: 20090263368
    Abstract: The present invention relates to a method for determining likelihood of an individual of developing a psychiatric disorder. More particularly, the method of the invention is based on the identification of genetic variations in genes involved in the modulation of melatonin and their consequences on such pathway for the determination of whether an individual is susceptible of being afflicted by a psychiatric disorder such as autism spectrum disorders (ASD), Deficits and Hyper Activity Disorder (ADHD) and anorexia.
    Type: Application
    Filed: October 13, 2006
    Publication date: October 22, 2009
    Applicant: Institut Pasteur
    Inventors: Thomas Bourgeron, Jonas Melke, Hany Goubran Botros, Jean-Marie Launay, Marion Leboyer, Christopher Gillberg, Pauline Chaste, Richard Delorme
  • POLYNUCLEOTIDE AND PROTEIN INVOLVED IN SYNAPTOGENESIS, VARIANTS THEREOF, AND THEIR THERAPEUTIC AND DIAGNOSTIC USES
    Publication number: 20090202992
    Abstract: The invention relates to a kit for diagnosing autism linked to a mutation in a protein belonging to the family of human neuroligins.
    Type: Application
    Filed: October 31, 2007
    Publication date: August 13, 2009
    Applicants: INST. NAT. DE LA SANTE ET DE LA RECHERCHE MEDICALE, INSTITUT PASTEUR, ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS
    Inventors: Thomas BOURGERON, Stephane Jamain, Helene Quach, Catalina Betancur, Marion Leboyer, Christopher Gillberg
  • POLYNUCLEOTIDE AND PROTEIN INVOLVED IN SYNAPTOGENESIS, VARIANTS THEREOF, AND THEIR THERAPEUTIC AND DIAGNOSTIC USES
    Publication number: 20090117554
    Abstract: The invention relates to a method and a kit for diagnosing autism linked to a mutation in a protein belonging to the family of human neuroligins.
    Type: Application
    Filed: October 31, 2007
    Publication date: May 7, 2009
    Applicants: INST. NAT. DE LA SANTE ET DE LA RECHERCHE MEDICALE, INSTITUT PASTEUR, ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS
    Inventors: Thomas BOURGERON, Stephane JAMAIN, Helene QUACH, Catalina BETANCUR, Marion LEBOYER, Christopher GILLBERG
  • Polynucleotide and protein involved in synaptogenesis variants thereof and their therapeutic and diagnostic uses
    Patent number: 7384740
    Abstract: The present invention provides a method of diagnosing autism linked to a mutation in the polynucleotide of SEQ ID NO: 12 or the polypeptide of SEQ ID NO: 14, or a propensity therefor, in a human, where the mutation results in altered synapse formation.
    Type: Grant
    Filed: December 2, 2002
    Date of Patent: June 10, 2008
    Assignees: Institut National de la Sante et de la Recherche Medicale (Inserm), Institut Pasteur, Assistance Publique-Hopitaux de Paris
    Inventors: Thomas Bourgeron, Stephane Jamain, Helene Quach, Catalina Betancur, Marion Leboyer, Christopher Gillberg
  • Polynucleotide and protein involved in synaptogenesis variants thereof and their therapeutic and diagnostic uses
    Publication number: 20050118588
    Abstract: The invention concerns identification of human genes coding for a protein involved in synaptogenesis and whereof the mutation is associated in humans with the development of neurological diseases and/or predisposition to developing mental disorders or psychiatric diseases such as autism and asparagus syndrome. More particularly, the invention concerns a protein belonging to the family of human neuroligins (HNL's) and more particularly the HNL4X protein and its functional homologue HNL4Y encoded by a Y chromosome gene. The invention also concerns polynucleotides coding for the HNL4X and HNL4Y proteins mutated or not and mutated HNL3 proteins, the cellular expression vectors comprising the nucleic acid sequences expressing HNL3, HNL4X, HNL4Y mutated or not, and the polyclonal or monoclonal antibodies capable of being fixed on one of said peptides and/or polynucleotides mentioned above.
    Type: Application
    Filed: December 2, 2002
    Publication date: June 2, 2005
    Inventors: Thomas Bourgeron, Stephane Jamain, Helene Quach, Catalina Betancur, Marion Leboyer, Christopher Gillberg