Abstract: A method and apparatus for iterative computer-mediated collaborative synthesis and analysis synthesizes a first focus topic in accordance with ideas collected from a plurality of cooperating users. The first focus topic triggers an analysis of that focus topic. The conclusions of this analysis indicate shortcomings in the first focus topic and trigger a further synthesis of the first focus topic. The further synthesis results trigger further analysis, and so on, on an iterative basis. The cooperating users follow a process template comprises of a scripted series of synthesis and analysis activities. Facilitation support is provided to the cooperating users to assist the cooperating users in accomplishing each activity in sequence. In further embodiments, a second focus topic is synthesized in response to the conclusion implied by the analysis of the first focus topic, and an analysis of the second focus topic is triggered.

Abstract: A dynamic quote window for a securities system includes a quote montage that displays quotes from market participants to buy or sell a security and a plurality of controls disposed proximate to the quote montage, each of the controls displaying a price level and aggregated quote size at the price level for the security. The aggregate controls display aggregated quotes at various price levels that represents publically displayed, available liquidity. Market participants can see the depth of the quotes at the inside. Also described in a multi-order window which when populated and transmitted can generate orders to capture all shares available at the price corresponding to the aggregate interest control depressed and better.

Abstract: A method and apparatus for facilitating computer-supported collaborative work sessions solicits ideas from participants in a collaborative work session, and then prompts the participants to group the generated ideas into discrete clusters of related ideas. The participants' clusters are then aggregated to form collective clusters that represent overarching themes or ideas generated in the collaborative work session. The collective clusters and the ideas contained therein may be used by an organization, for example to address a specific need or to shape a policy.

Abstract: The present invention provides a process for determining genotypes in highly polymorphic systems by polymerase chain reaction amplification of CDNA or genomic DNA and direct sequencing polymerase chain reaction products using oligonucleotide primers. More specifically, Class II and Class I HLA genotypes can be unambiguously determined in any subject in 16-24 hours by direct sequencing of DRB, DQB, DQA, DPB, DPA, HLA-A, HLA-B and HLA-C- transcripts enzymatically amplified using a limited number of non-allele-specific oligonucleotides. Total cellular RNA from peripheral blood mononuclear cells is reverse transcribed using antisense primers, specific for different locus (DQB, DQA, DPA or DPB) or group of loci (DRB1-5, or HLA-A and HLA-B and HLA-C). The synthesized cDNA molecules are then enzymatically amplified using different combinations of oligonucleotides for each locus and directly sequenced with Taq polymerase using an internal oligonucleotide. The sequenced genes are then analyzed.