Abstract: A peripheral component interconnect express PCI-e network system having a processor for (a) assigning addresses to the PCI-e topology tree, comprising: traversing, at a given level and in a breadth direction, down-link couplings to an interconnection; ascertaining, at the level, which of the down-link couplings are connected to nodes; assigning, at the level, addresses to nodes of ascertained down-link coupling having nodes; and (b) propagating, a level, comprising: traversing, at the level and in a depth direction, down-link couplings to the interconnection of the PCI-e network, ascertaining, at the level, which of the downlink couplings are coupled to other interconnections in the depth direction, consecutively proceeding in the depth direction, to a next level of the down-link coupling of a next interconnection; and alternatively repeating (a) and (b) until the nodes are assigned addresses within the PCI-e tree topology network.

Abstract: In a high-dimensional PCI-Express (PCIe) network, implementation of alternative paths is accomplished to facilitate flexible topology implementation and network domain scaling while enabling improved communication latency. Different portions of the PCIe tree structure are connected to allow a shorter path for communications by utilizing a bridge circuit configured as an end-point with respect to two switches that are not directly connected in the PCIe tree topology. The bridge circuit performs address translations to allow communications from one switch to be passed via the bridge circuit to the other switch.

Abstract: An apparatus for initialization. The apparatus includes a management I/O device controller for managing initialization of a plurality of I/O devices coupled to a PCI-Express (PCIe) fabric. The management I/O device controller is configured for receiving a request to register a target interrupt register address of a first worker computing resource, wherein the target interrupt register address is associated with a first interrupt generated by a first I/O device coupled to the PCIe fabric. A mapping module of the management I/O device controller is configured for mapping the target interrupt register address to a mapped interrupt register address of a domain in which the first I/O device resides. A translating interrupt register table includes a plurality of mapped interrupt register addresses in the domain that is associated with a plurality of target interrupt register addresses of a plurality of worker computing resources.

Abstract: A method for accessing a device in a primary peripheral component interconnect express (PCIe) domain from a secondary PCIe domain includes determining which one or more virtual functions of the device in the primary PCIe domain are to be made available to the secondary PCIe domain. A virtual function driver is installed in the primary PCIe domain associated with the one or more virtual functions. Information corresponding to the one or more virtual functions is provided to the secondary PCIe domain. A virtual function driver associated with the one or more virtual functions is installed in the secondary PCIe domain from the information. The virtual function driver in the secondary PCIe domain has same properties as the virtual function driver in the primary PCIe domain. The device in the primary PCIe domain is accessed from the virtual function driver in the secondary PCIe domain.

Abstract: An apparatus for initialization. The apparatus includes a management I/O device controller for managing initialization of a plurality of I/O devices coupled to a PCI-Express (PCIe) fabric. The management I/O device controller is configured for receiving a request to register a target interrupt register address of a first worker computing resource, wherein the target interrupt register address is associated with a first interrupt generated by a first I/O device coupled to the PCIe fabric. A mapping module of the management I/O device controller is configured for mapping the target interrupt register address to a mapped interrupt register address of a domain in which the first I/O device resides. A translating interrupt register table includes a plurality of mapped interrupt register addresses in the domain that is associated with a plurality of target interrupt register addresses of a plurality of worker computing resources.

Abstract: Apparatus and method for controlling an electric motor providing assistance to a bicycle rider based on measuring the mechanical power generated by the rider. The power generated by the rider is measured by measuring tension in a bicycle chain (or belt) and RPM. A chain (or belt) roller is carried at the free end of a cantilevered beam and the chain (or belt) rides over the roller. The resulting deflection of the cantilevered beam provides a measurement of chain tension. A control signal for the electric motor is generated based on a smoother version of the power generated by the rider.

Abstract: Embodiments of the present invention provide a solution for managing inter-domain resource allocation in a Peripheral Component Interconnect-Express (PCIe) network. One processor among a plurality of link processors is elected as a management processor. The management processor obtains information about available resources of PCIe network. When a resource request from a request processor is received, the management processor allocates a resource of the available resources to the requesting processor. The management processor instructs one or more link processors to program one or more inter-domain NTBs through which the traffic between the allocated resource and the requesting processor is going to flow according to the memory address information of the allocated resource, to allow cross-domain resource access between the requesting processor and the allocated resource.

Abstract: Apparatus and method for controlling an electric motor providing assistance to a bicycle rider based on measuring the mechanical power generated by the rider. The power generated by the rider is measured by measuring tension in a bicycle chain (or belt) and RPM. A chain (or belt) roller is carried at the free end of a cantilevered beam and the chain (or belt) rides over the roller. The resulting deflection of the cantilevered beam provides a measurement of chain tension. A control signal for the electric motor is generated based on a smoother version of the power generated by the rider.

Abstract: The use of N-(3-methoxy-5-methylpyrazin-2-yl)-2-(4-[1,3,4-oxadiazol-2-yl]phenyl)pyridine-3-sulphonamide, or a pharmaceutically acceptable salt thereof, in the treatment of cancer and/or pain in a warm blooded animal such as man is described.

Abstract: The use of N-(3-methoxy-5-methylpyrazin-2-yl)-2-(4-[1,3,4-oxadiazol-2-yl]phenyl)pyridine-3-sulphonamide, or a pharmaceutically acceptable salt thereof, in the treatment of cancer and/or pain in a warm blooded animal such as man is described.

Abstract: A combination, comprising N-(3-methoxy-5-methylpyrazin-2-yl)-2-(4-[1,3,4-oxadiazol-2-yl]phenyl)pyridine-3-sulphonamide and an anti-mitotic cytotoxic agent.

Abstract: The invention concerns compounds of formula (I), wherein each of R1, R2, R3, R4, R5, R6, R8, R9, R10 m, n, p, X, Y and Z have any meanings defined in the description, processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use as an anti-proliferative agent in the treatment of solid tumor disease.

Abstract: The invention relates to a group of novel indole compounds of Formula (I): wherein: R1, R2, R4, R6, R6a, R7, R8, R9, R10, and A are as defined in the specification, which are useful as gonadotrophin releasing hormone antagonists. The invention also relates to pharmaceutical formulations of said compounds, methods of treatment using said compounds and to processes for the preparation of said compounds.

Abstract: The invention provides a compound of Formula (Ia), or a pharmaceutically acceptable salt thereof, a process for t he preparation of a compound of Formula (1a) and pharmaceutical compositions of a compound of Formula (1a).

Abstract: The invention concerns compounds of formula (I), wherein each of R1, R2, R3, R4, R5, R6, R8, R9, R10 m, n, p, X, Y and Z have any meanings defined in the description, processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use as an anti-proliferative agent in the treatment of solid tumour disease.

Abstract: Arc chambers for discharge lamps, such as ceramic metal halide lamps, have ends, where the electrodes for the arc chambers are introduced, that are configured such that, when the arc chambers are arranged vertically, the metal halide additives in the arc chambers will accumulate substantially only on the inner surfaces of the ends, which can have closure walls that are thicker than the thickness of the walls of the body portions of the arc chambers. The ends can be further configured such that the metal halides are deposited substantially uniformly in a thin layer over the ends of the arc chambers. The ends can also be configured in a manner that no sharp edges are provided at the ends of the arc chambers so that corrosive effects to the arc chamber resulting from localized temperature variations are minimized.

Abstract: A plant variety of the Cactaceae family, Schlumbergera truncata, called ‘Harmony’ having a deep colored bloom characterized as R.H.S 46 B (red group). The new variety has a strong resistance to bud abscission, a strong propensity for buds to mature and flower, an erect growth habit, and an ability to grow well in relatively cold temperatures.

Abstract: A variety of the Cactaceae family produced in a controlled hybridization ‘Elsie’. The variety possesses the desirable characteristics of: a strong growth habit with erect stems; a red colored bloom; relatively large flowers; a strong propensity to branch with minimal pruning; and flowers that stay open for as long as two weeks.

Abstract: This invention relates to compounds of formula (I) that inhibit farnesylation of gene products through inhibition of the enzyme farnesyl-protein transferase (FPTase). The invention also relates to methods of manufacturing the compounds, pharmaceutical compositions and methods of treating diseases, especially cancer, which are mediated through farnesylation.

Abstract: A test system for proportioning fire fighting and fire suppression systems is provided. This test system includes a foam-water proportioning system and at least one test apparatus connectable to or incorporated into the foam-water sprinkler system. In an exemplary embodiment, the foam-water proportioning system further includes: (i) at least one proportioning valve; (ii) at least one source of water; and (iii) at least one source of foam concentrate. The test apparatus further includes: (i) a means for bypassing the at least one source of foam concentrate; (ii) a first flow meter; and (iii) an optional second flow meter.