Abstract: Disclosed herein is a test rover apparatus, a test system and a test method using the test rover apparatus. For example, the test rover apparatus is provided with a chassis that is configured to support an object representing a mobile actor, and a motor that is coupled to at least one wheel. At least one spring is coupled between the at least one wheel and the chassis to: bias the at least one wheel to extend out of the cavity to engage an underlying surface, and compress in response to a load being applied to the top of the chassis thereby retracting the at least one wheel into the cavity. A controller is configured to control the motor to drive the at least one wheel to propel the chassis along a predetermined route that is based on simulation data and corresponds to a maneuver of the mobile actor.

Abstract: An aftertreatment device includes flow guides disposed within a dosing conduit. Exhaust enters through a perforated region of the dosing conduit and passes through the flow guides. The flow guides induce swirling or other turbulence to mix injected reactant with the exhaust gas. Various types of flow guides include cantilevered vanes, guide passageways, and louvered openings of a second conduit. Some types of flow guides induce localized mixing to inhibit deposit formation at the doser mounting unit. Other types of flow guides induce mixing downstream of the dosing conduit.

Abstract: This disclosure relates to novel crystalline forms of N-(4-(1-(2,6-difluorobenzyl)-5-((dimethylamino)methyl)-3-(6-methoxy-3-pyridazinyl)-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-6-yl)phenyl)-N?-methoxyurea. It also relates to methods of making the disclosed crystalline forms, pharmaceutical compositions and kits comprising them, and methods of treatment and uses comprising their administration.

Abstract: An aftertreatment device includes flow guides disposed within a dosing conduit. Exhaust enters through a perforated region of the dosing conduit and passes through the flow guides. The flow guides induce swirling or other turbulence to mix injected reactant with the exhaust gas. Various types of flow guides include cantilevered vanes, guide passageways, and louvered openings of a second conduit. Some types of flow guides induce localized mixing to inhibit deposit formation at the doser mounting unit. Other types of flow guides induce mixing downstream of the dosing conduit.

Abstract: An exhaust treatment arrangement includes a mixing assembly disposed between first and second substrates; and an injection mounting location disposed at the mixing assembly. The mixing assembly includes a mixing arrangement configured to direct exhaust flow exiting the first substrate in a swirling configuration, a restricting member defining a restricted passage, and optionally a dispersing member configured to even out the exhaust flow.

Abstract: A dosing and mixing arrangement including an exhaust conduit defining a central axis; a mixing conduit positioned within the exhaust conduit; a dispersing arrangement (e.g., a mesh) disposed at the upstream end of the mixing conduit; an injector coupled to the exhaust conduit and configured to direct reactants into the exhaust conduit towards the mesh; and an annular bypass defined between the mixing conduit and the exhaust conduit for allowing exhaust to bypass the upstream end of the mixing conduit and to enter the mixing conduit downstream of the mesh.

Abstract: An exhaust treatment arrangement includes a mixing assembly disposed between first and second substrates; and an injection mounting location disposed at the mixing assembly. The mixing assembly includes a mixing arrangement configured to direct exhaust flow exiting the first substrate in a swirling configuration, a restricting member defining a restricted passage, and optionally a dispersing member configured to even out the exhaust flow.

Abstract: An exhaust treatment arrangement includes a mixing assembly disposed between first and second substrates; and an injection mounting location disposed at the mixing assembly. The mixing assembly includes a mixing arrangement configured to direct exhaust flow exiting the first substrate in a swirling configuration, a restricting member defining a restricted passage, and optionally a dispersing member configured to even out the exhaust flow.

Abstract: A dosing and mixing arrangement including an exhaust conduit defining a central axis; a mixing conduit positioned within the exhaust conduit; a dispersing arrangement (e.g., a mesh) disposed at the upstream end of the mixing conduit; an injector coupled to the exhaust conduit and configured to direct reactants into the exhaust conduit towards the mesh; and an annular bypass defined between the mixing conduit and the exhaust conduit for allowing exhaust to bypass the upstream end of the mixing conduit and to enter the mixing conduit downstream of the mesh.

Abstract: A dosing and mixing arrangement including an exhaust conduit defining a central axis; a mixing conduit positioned within the exhaust conduit; a dispersing arrangement (e.g., a mesh) disposed at the upstream end of the mixing conduit; an injector coupled to the exhaust conduit and configured to direct reactants into the exhaust conduit towards the mesh; and an annular bypass defined between the mixing conduit and the exhaust conduit for allowing exhaust to bypass the upstream end of the mixing conduit and to enter the mixing conduit downstream of the mesh.

Abstract: Measuring apparatus-calibration device for calibrating a measuring apparatus-temperature sensor of a, in particular optical, measuring apparatus, wherein the measuring apparatus-calibration device comprises a, preferably measuring apparatus-external, calibration-temperature sensor, which is traceably calibratable itself, for determining a calibration temperature in the region of a measuring surface of the measuring apparatus and a determination unit which is adapted for determining an information which is indicative for a discrepancy between a measuring apparatus-temperature which is captured by the measuring apparatus-temperature sensor in the region of the measuring surface and the calibration temperature, on whose basis the measuring apparatus-temperature sensor is calibratable.

Abstract: A dosing and mixing arrangement including an exhaust conduit defining a central axis; a mixing conduit positioned within the exhaust conduit; a dispersing arrangement (e.g., a mesh) disposed at the upstream end of the mixing conduit; an injector coupled to the exhaust conduit and configured to direct reactants into the exhaust conduit towards the mesh; and an annular bypass defined between the mixing conduit and the exhaust conduit for allowing exhaust to bypass the upstream end of the mixing conduit and to enter the mixing conduit downstream of the mesh.

Abstract: A dosing and mixing arrangement including an exhaust conduit defining a central axis; a mixing conduit positioned within the exhaust conduit; a dispersing arrangement (e.g., a mesh) disposed at the upstream end of the mixing conduit; an injector coupled to the exhaust conduit and configured to direct reactants into the exhaust conduit towards the mesh; and an annular bypass defined between the mixing conduit and the exhaust conduit for allowing exhaust to bypass the upstream end of the mixing conduit and to enter the mixing conduit downstream of the mesh.

Abstract: An exhaust treatment arrangement includes a mixing assembly disposed between first and second substrates; and an injection mounting location disposed at the mixing assembly. The mixing assembly includes a mixing arrangement configured to direct exhaust flow exiting the first substrate in a swirling configuration, a restricting member defining a restricted passage, and optionally a dispersing member configured to even out the exhaust flow.

Abstract: Measuring apparatus-calibration device for calibrating a measuring apparatus-temperature sensor of a, in particular optical, measuring apparatus, wherein the measuring apparatus-calibration device comprises a, preferably measuring apparatus-external, calibration-temperature sensor, which is traceably calibratable itself, for determining a calibration temperature in the region of a measuring surface of the measuring apparatus and a determination unit which is adapted for determining an information which is indicative for a discrepancy between a measuring apparatus-temperature which is captured by the measuring apparatus-temperature sensor in the region of the measuring surface and the calibration temperature, on whose basis the measuring apparatus-temperature sensor is calibratable.

Abstract: A dosing and mixing arrangement including an exhaust conduit defining a central axis; a mixing conduit positioned within the exhaust conduit; a dispersing arrangement (e.g., a mesh) disposed at the upstream end of the mixing conduit; an injector coupled to the exhaust conduit and configured to direct reactants into the exhaust conduit towards the mesh; and an annular bypass defined between the mixing conduit and the exhaust conduit for allowing exhaust to bypass the upstream end of the mixing conduit and to enter the mixing conduit downstream of the mesh.

Abstract: An internal combustion engine having at least one cylinder with a reciprocating piston, and in which the cylinder head and the cylinder block are integrally arranged as a head-block unit, having at least one exhaust-gas turbocharger.

Abstract: A cylinder head (1) for an internal combustion engine with liquid cooling and a liquid-cooled exhaust manifold (8) and which is arranged integrally with the cylinder head (1) includes at least one first and one second cooling chamber (4, 9) through which a coolant flows, and with the region of the exhaust manifold (8) being enclosed at least partly by the second cooling chamber. In order to ensure by way of simple production the optimal removal of heat from thermally critical regions, the first and second cooling chambers are flow-connected via at least one borehole (10) with one another.

Abstract: A cylinder head (1) for an internal combustion engine with liquid cooling and a liquid-cooled exhaust manifold (8) and which is arranged integrally with the cylinder head (1) includes at least one first and one second cooling chamber (4, 9) through which a coolant flows, and with the region of the exhaust manifold (8) being enclosed at least partly by the second cooling chamber. In order to ensure by way of simple production the optimal removal of heat from thermally critical regions, the first and second cooling chambers are flow-connected via at least one borehole (10) with one another.

Abstract: The present invention relates to a method of forming granules of (2R,3S,4R,5R)-5-(4-amino-2-oxo-2H-pyrimidin-1-yl)-2-azido-3,4-bis-iso-butyryloxy-tetrahydro-furan-2-ylmethyl isobutyrate; hydrochloride salt (I), comprising mixing I, with a granulating amount of a granulating liquid, and a polyethylene glycol (PEG)/polypropylene glycol (PPG) block copolymer as a binder and solubility enhancer to form wet granules which are then dried to remove the granulating liquid.