Patents by Inventor Thomas Budde Hansen

Thomas Budde Hansen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Virus Filtration of Liquid Factor VII Compositions
    Publication number: 20220064605
    Abstract: The present invention relates to a novel method for improving the viral safety of liquid Factor VII compositions, in particular those comprising active Factor VII polypeptides (a Factor VIIa polypeptide).
    Type: Application
    Filed: November 9, 2021
    Publication date: March 3, 2022
    Inventors: Jesper Christensen, Erik Halkjaer, Turid Preuss, Thomas Budde Hansen, Lene Vaedele Madsen Tomoda, Nina Johansen
  • Method for thioether conjugation of proteins
    Patent number: 11219690
    Abstract: The invention relates to methods for obtaining a protein conjugate wherein a cysteine residue of the protein serves as attachment point for the chemical moiety conjugated to the protein.
    Type: Grant
    Filed: December 15, 2014
    Date of Patent: January 11, 2022
    Assignee: Novo Nordisk Healthcare AG
    Inventors: Charlotte Schou Hunneche, Thomas Budde Hansen, Ernst Broberg Hansen
  • Virus filtration of liquid factor VII compositions
    Publication number: 20200248150
    Abstract: The present invention relates to a novel method for improving the viral safety of liquid Factor VII compositions, in particular those comprising active Factor VII polypeptides (a Factor VIIa polypeptide).
    Type: Application
    Filed: April 20, 2020
    Publication date: August 6, 2020
    Inventors: Jesper Christensen, Erik Halkjaer, Turid Preuss, Thomas Budde Hansen, Lene Vaedele Madsen Tomoda, Nina Johansen
  • Virus filtration of liquid factor VII compositions
    Publication number: 20190032026
    Abstract: The present invention relates to a novel method for improving the viral safety of liquid Factor VII compositions, in particular those comprising active Factor VII polypeptides (a Factor VIIa polypeptide).
    Type: Application
    Filed: September 28, 2018
    Publication date: January 31, 2019
    Inventors: Jesper Christensen, Erik Halkjaer, Turid Preuss, Thomas Budde Hansen, Lene Vaedele Madsen Tomoda, Nina Johansen
  • Methods of optimizing chromatographic separation of polypeptides
    Patent number: 9766217
    Abstract: Described are methods for determination of peptide specific parameter(s) of a mixture comprising a target peptide and a related impurity (or impurities) to be used in a simulation model of chromatographic separation using mathematical model(s). Also described are chromatographic simulation methods using above determined parameters, as well as computer systems and computer programs for performing one or more of the above method(s).
    Type: Grant
    Filed: September 8, 2007
    Date of Patent: September 19, 2017
    Assignee: Novo Nordisk A/S
    Inventors: Steffen Kidal, Thomas Budde Hansen, Arne Staby
  • Virus Filtration of Liquid Factor VII Compositions
    Publication number: 20170022482
    Abstract: The present invention relates to a novel method for improving the viral safety of liquid Factor VII compositions, in particular those comprising active Factor VII polypeptides (a Factor VIIa polypeptide).
    Type: Application
    Filed: October 5, 2016
    Publication date: January 26, 2017
    Inventors: Jesper Christensen, Erik Halkjaer, Turid Preuss, Thomas Budde Hansen, Lene Vaedele Madsen Tomoda, Nina Johansen
  • Method for Thioether Conjugation of Proteins
    Publication number: 20160303248
    Abstract: The invention relates to methods for obtaining a protein conjugate wherein a cysteine residue of the protein serves as attachment point for the chemical moiety conjugated to the protein.
    Type: Application
    Filed: December 15, 2014
    Publication date: October 20, 2016
    Applicant: Novo Nordisk Health Care AG
    Inventors: Charlotte Schou Hunneche, Thomas Budde Hansen, Ernst Broberg Hansen
  • Reduction of the content of protein contaminants in compositions comprising a vitamin K-dependent protein of interest
    Patent number: 9187549
    Abstract: The present invention relates to Vitamin K-dependent protein compositions having a very low, or negligible, content of protein contaminants. The present invention also relates to method applicable in the preparation of such Vitamin K-dependent protein compositions. Such methods may either be used alone or in sequential combination with the purpose of reducing the relative content of protein contaminants. The present invention is particularly relevant in the preparation of compositions of coagulation factors selected from Factor X polypeptides (FX/FXa), Factor IX polypeptides (FIX/FIXa), Factor VII polypeptides (FVII/FVIIa), and the anticoagulant Protein C, in particular Factor VII polypeptides.
    Type: Grant
    Filed: December 23, 2005
    Date of Patent: November 17, 2015
    Assignee: Novo Nordisk Healthcare A/G
    Inventors: Janus Krarup, Thomas Budde Hansen, Anne Charlotte Arentsen, Daniel E. Rasmussen, Are Bogsnes, Arne Staby, Haleh Ahmadian, Susanne Bang
  • Virus Filtration of Liquid Factor VII Compositions
    Publication number: 20150299685
    Abstract: The present invention relates to a novel method for improving the viral safety of liquid Factor VII compositions, in particular those comprising active Factor VII polypeptides (a Factor VIIa polypeptide).
    Type: Application
    Filed: June 29, 2015
    Publication date: October 22, 2015
    Inventors: Jesper Christensen, Erik Halkjaer, Turid Preuss, Thomas Budde Hansen, Lene Vaedele Madsen Tomoda, Nina Johansen
  • Virus filtration of liquid factor VII compositions
    Patent number: 9102762
    Abstract: The present invention relates to a novel method for improving the viral safety of liquid Factor VII compositions, in particular those comprising active Factor VII polypeptides (a Factor VIIa polypeptide).
    Type: Grant
    Filed: January 13, 2012
    Date of Patent: August 11, 2015
    Assignee: Novo Nordisk Healthcare AG
    Inventors: Jesper Christensen, Erik Halkjær, Turid Preuss, Thomas Budde Hansen, Lene Vædele Madsen Tomoda, Nina Johansen
  • PURIFICATION OF PEPTIDES PREPARED BY SOLID PHASE SYNTHESIS
    Publication number: 20120149868
    Abstract: The invention relates to an effective process for purifying a peptide which has been prepared by solid phase peptide synthesis. Also encompassed by the invention is a kit comprising reagents for said process and the purified peptide obtained by said process.
    Type: Application
    Filed: May 15, 2009
    Publication date: June 14, 2012
    Applicant: Novo Nordisk A/S
    Inventors: Camilla Kornbeck, Thomas Budde Hansen
  • VIRUS FILTRATION OF LIQUID FACTOR VII COMPOSITIONS
    Publication number: 20120115204
    Abstract: The present invention relates to a novel method for improving the viral safety of liquid Factor VII compositions, in particular those comprising active Factor VII polypeptides (a Factor VIIa polypeptide).
    Type: Application
    Filed: January 13, 2012
    Publication date: May 10, 2012
    Applicant: Novo Nordisk Healthcare A/G
    Inventors: Jesper Christensen, Erik Halkjaer, Turid Preuss, Thomas Budde Hansen, Lene Vaedele Madsen Tomoda, Nina Johansen
  • ANTIBODY PURIFICATION PROCESS
    Publication number: 20110105725
    Abstract: The invention concerns a method for the industrial production of antibodies.
    Type: Application
    Filed: May 15, 2009
    Publication date: May 5, 2011
    Inventors: Bjarne Rønfeldt Nielsen, Hanne Christensen, Daniel E. Rasmussen, Thomas Budde Hansen, John Strikart Nielsen, Erik Halkjaer, Rikke Christina Nielsen, Christina Jespersgaard, Arne Staby
  • Separation of polypeptides comprising a racemized amino acid
    Patent number: 7749955
    Abstract: Method for purifying a racemized polypeptide by ion-exchange chromatography.
    Type: Grant
    Filed: February 21, 2006
    Date of Patent: July 6, 2010
    Assignee: Novo Nordisk A/S
    Inventors: Thomas Budde Hansen, Steffen Kidal, Camilla Kornbeck
  • Methods of Optimizing Chromatographic Separation of Polypeptides
    Publication number: 20100004907
    Abstract: Described are methods for determination of peptide specific parameter(s) of a mixture comprising a target peptide and a related impurity (or impurities) to be used in a simulation model of chromatographic separation using mathematical model(s). Also described are chromatographic simulation methods using above determined parameters, as well as computer systems and computer programs for performing one or more of the above method(s).
    Type: Application
    Filed: September 8, 2007
    Publication date: January 7, 2010
    Applicant: NOVO NORDISK A/S
    Inventors: Steffen Kidal, Thomas Budde Hansen, Arne Staby
  • Virus Filtration of Liquid Factor VII Compositions
    Publication number: 20080274534
    Abstract: The present invention relates to a novel method for improving the viral safety of liquid Factor VII compositions, in particular those comprising active Factor VII polypeptides (a Factor VIIa polypeptide).
    Type: Application
    Filed: July 15, 2008
    Publication date: November 6, 2008
    Applicant: Novo Nordisk HealthCare A/G
    Inventors: Jesper Christensen, Erik Halkjaer, Turid Preuss, Thomas Budde Hansen, Lene Vaedele Madsen Tomoda, Nina Johansen
  • Reduction of the Content of Protein Contaminents in Compositions Comprising a Vitamin K-Dependent Protein of Interest
    Publication number: 20080207880
    Abstract: The present invention relates to Vitamin K-dependent protein compositions having a very low, or negligible, content of protein contaminants. The present invention also relates to method applicable in the preparation of such Vitamin K-dependent protein compositions. Such methods may either be used alone or in sequential combination with the purpose of reducing the relative content of protein contaminants. The present invention is particularly relevant in the preparation of compositions of coagulation factors selected from Factor X polypeptides (FX/FXa), Factor IX polypeptides (FIX/FIXa), Factor VII polypeptides (FVII/FVIIa), and the anticoagulant Protein C, in particular Factor VII polypeptides.
    Type: Application
    Filed: December 23, 2005
    Publication date: August 28, 2008
    Applicant: Novo Nordisk HealthCare A/G
    Inventors: Janus Krarup, Thomas Budde Hansen, Anne Charlotte Arentsen, Daniel E. Rasmussen, Are Bognes, Arne Staby, Haleh Ahmadian, Susanne Bang