Abstract: A method for predicting the presence of melanoma comprises performing molecular profiling of at least one of genomic and transcriptomic material extracted from a skin swab sample collected from a lesion of a patient, extracting one or more biological features from the molecular profiling, comparing the one or more extracted biological features to one or more biological features corresponding to one or more reference skin swab samples collected from a plurality of reference patients, and predicting, based on the comparing, whether the lesion of the patient is cancerous.

Abstract: Short fixed length sub-sequences, defined as reference sub-sequences, are extracted from a collection of reference sequences, and an index is constructed showing which short fixed length reference sub-sequence occurs in which reference sequences. Short fixed length sub-sequences, the same length as the reference sub-sequences and defined as source sub-sequences, are extracted from a collection of source sequences derived from a sample for which the signature is to be determined, and the short fixed length source sub-sequences are compiled to determine the frequency of each within the collection. The presence or absence of source sub-sequences in combination with the index is used to infer the presence or absence of reference sequences from the reference collection.

Abstract: One or more sequences are decomposed into one or more fixed length subsequences. The one or more sequences are associated with one or more respective genome samples. One or more contiguous ranges of the one or more fixed length subsequences are identified. A given one of the one or more contiguous ranges is analyzed to identify at least one group of variants of the fixed length subsequences within the given contiguous range. Analyzing the given contiguous range to identify the at least one group of variants comprises comparing the one or more fixed length subsequences of the given contiguous range to each other. It is determined whether the at least one group of variants partitions the one or more genome samples in satisfaction of at least one partitioning criterion.

Abstract: A method for predicting the presence of melanoma comprises performing molecular profiling of at least one of genomic and transcriptomic material extracted from a skin swab sample collected from a lesion of a patient, extracting one or more biological features from the molecular profiling, comparing the one or more extracted biological features to one or more biological features corresponding to one or more reference skin swab samples collected from a plurality of reference patients, and predicting, based on the comparing, whether the lesion of the patient is cancerous.

Abstract: Short fixed length sub-sequences, defined as reference sub-sequences, are extracted from a collection of reference sequences, and an index is constructed showing which short fixed length reference sub-sequence occurs in which reference sequences. Short fixed length sub-sequences, the same length as the reference sub-sequences and defined as source sub-sequences, are extracted from a collection of source sequences derived from a sample for which the signature is to be determined, and the short fixed length source sub-sequences are compiled to determine the frequency of each within the collection. The presence or absence of source sub-sequences in combination with the index is used to infer the presence or absence of reference sequences from the reference collection.

Abstract: Short fixed length sub-sequences, defined as reference sub-sequences, are extracted from a collection of reference sequences, and an index is constructed showing which short fixed length reference sub-sequence occurs in which reference sequences. Short fixed length sub-sequences, the same length as the reference sub-sequences and defined as source sub-sequences, are extracted from a collection of source sequences derived from a sample for which the signature is to be determined, and the short fixed length source sub-sequences are compiled to determine the frequency of each within the collection. The presence or absence of source sub-sequences in combination with the index is used to infer the presence or absence of reference sequences from the reference collection.

Abstract: Short fixed length source sub-sequences are extracted from a collection of source sequences derived from a sample for which the biological signature is to be determined. The extracted short fixed length source sub-sequences are compiled to determine the frequency of each within the collection. Overlaps between the short fixed length source sub-sequences are used to find a chain of overlaps from one or more sub-sequences equivalent to a pre-flanking reference marker sequence to one or more sub-sequences equivalent to a post-flanking reference marker sequence, wherein the reference marker sequences flank a region containing a repetitive sequence region.

Abstract: Short fixed length source sub-sequences are extracted from a collection of source sequences derived from a sample for which the biological signature is to be determined. The extracted short fixed length source sub-sequences are compiled to determine the frequency of each within the collection. Overlaps between the short fixed length source sub-sequences are used to find a chain of overlaps from one or more sub-sequences equivalent to a pre-flanking reference marker sequence to one or more sub-sequences equivalent to a post-flanking reference marker sequence, wherein the reference marker sequences flank a region containing a repetitive sequence region.