Abstract: A porous chemically activated medium having a low affinity for peptide group-containing materials is provided comprising a porous polymeric medium having a low affinity for peptide group-containing materials covalently bound to a residue of an activating agent which is capable of reacting with an acceptor molecule.

Abstract: A device for the depletion of the leucocyte content in a platelet concentrate, preferably comprising a modified porous, fibrous medium with a critical wetting surface tension of at least about 90 dynes/cm and a method for the depletion of the leucocyte content and platelet concentrate comprising passing the platelet concentrate through the porous medium.

Abstract: A method of reducing the adhesion of bubbles to the surfaces of a medical administration set with which a parenteral liquid comes in contact prior to its introduction into a patient by treating the surfaces of the medical administration set with which the liquid comes in contact to increase the critical surface tension thereof prior to contacting the surfaces of the medical administration set with the liquid, preferably by radiation grafting with a solution of a monofunctional monomer compound.

Abstract: A supported microporous membrane comprising a composite of a microporous membrane and a synthetic thermoplastic web of microfibers secured to the membrane without the use of added adhesive components and having an ASTM D903 peel strength of at least about 2 grams per centimeter, the composite having a modulus of flexure at leasts 10 percent greater than that of the membrane, and the method of manufacturing such supported membranes by contacting thermplastic microfibers with the membrane while the microfibers are at an elevated temperature.

Abstract: A supported microporous membrane comprising a composite of a microporous membrane and a synthetic thermoplastic web of microfibers secured to the membrane without the use of added adhesive components and having an ASTM D903 peel strength of at least about 2 grams per centimeter, the composite having a modulus of flexure at least 10 percent greater than that of the membrane, and the method of manufacturing such supported membranes by contacting thermoplastic microfibers with the membrane while the microfibers are at an elevated temperature.

Abstract: Filter media comprised of charge modified, resin coated inorganic microfibers are prepared by mixing inorganic microfibers with an aqueous solution of a water soluble, noncolloidal cationic thermosetting binder resin to form a dispersion, following which a precipitating agent is added to precipitate the binder resin and coat the microfibers. The coated microfibers may be used in the dispersed or suspended form as a filter aid. Preferably they are formed into a filter sheet which is then dried and cured to form a filter sheet of narrowly distributed pore size, pore sizes as small as one-half micron, and having a positive zeta potential in alkaline media. Glass is the preferred microfiber and polyamine-epichlorohydrins the preferred resins. By providing the normally negative zeta potential microfibers with a positive zeta potential the binder resins used to coat the microfibers substantially enhance particulate removal capabilities of the microfiber filter sheet.

Abstract: Surface modified, skinless, hydrophilic, microporous, polyamide membranes with controlled surface properties are prepared by the steps of preparing a casting solution comprised of (A) a casting resin system comprised of (a) an alcohol-insoluble polyamide resin, and (b) a water-soluble membrane surface modifying polymer having functional polar groups and a molecular weight of 10,000 or greater, and (B) a solvent system in which the casting resin system is soluble; inducing nucleation of the casting solution by controlled addition of a nonsolvent for the casting resin system under controlled conditions to obtain a visible precipitate of casting resin system particles, thereby forming a casting composition; spreading the casting composition on a substrate to form a thin film; contacting and diluting the film of the casting composition with a liquid nonsolvent system for the casting resin system, thereby precipitating the casting resin system from the casting composition in the form of a thin, skinless, hydrophil

Abstract: Surface modified, skinless, hydrophilic, microporous, polyamide membranes are formed by preparing a casting solution comprised of (A) a casting resin system comprised of (a) an alcohol-insoluble polyamide resin, and (b) a cationic, water-soluble, quaternary ammonium, thermosetting, membrane surface modifying polymer, and (B) a solvent system in which the casting resin system is soluble; inducing nucleation of the casting solution by controlled addition of a nonsolvent for the casting resin system under controlled conditions to obtain a visible precipitate of casting resin system particles, thereby forming a casting composition; spreading the casting composition on a substrate to form a thin film; contacting and diluting the film of the casting composition with a liquid nonsolvent system for the casting resin system, thereby precipitating the casting resin system from the casting composition in the form of a thin, skinless, hydrophilic, surface modified, microporous, polyamide membrane; and washing and drying

Abstract: Polymeric microfibrous structures comprised of normally hydrophobic microfibers coated with a cured, precipitated, cationic, thermosetting binder resin or polymer and characterized by being hydrophilic and having a positive zeta potential with enhanced capability for the removal of negatively-charged particulate material in a fluid medium are prepared by a process comprising the steps:(1) combining in a controlled manner a first solution of a water-soluble, non-colloidal, cationic, thermosetting binder resin or polymer and a second solution or dispersion of a precipitating agent to form a stable emulsion or suspension;(2) impregnating the microfibrous structure of normally hydrophobic microfibers with the stable emulsion or suspension to form a fibrous structure wetted with the stable emulsion or suspension; and(3) drying the wetted microfibrous structure and curing the binder resin or polymer.

Abstract: A self-supporting structure comprising an inorganic sorbent and method for preparing is described in which the self-supporting structure is substantially free of sorbent fines and the sorption characteristics of the sorbent particles is retained. The process for immobilizing the sorbent particles in the self-supporting structure comprises the steps of:(a) preheating inorganic sorbent particles to an elevated temperature;(b) mixing the sorbent particles with particles of a polymeric binding material to form a mixture comprising the particles of polymeric binding material adhered to the sorbent particles; and(c) heating the mixture to about the solid-liquid transition temperature of the polymeric binding material with or without pressure to form a structure which upon cooling is self supporting.

Abstract: A process for immobilizing reactive Whetlerite carbon particles and forming a self-supporting structure of high compressive strength therefrom is described in which the self-supporting structure substantially eliminates the formation of carbon fines while retaining the adsorption characteristics of the carbon particles.

Abstract: Microfibrous, polymeric filter sheets and filter elements prepared therefrom comprised of a normally hydrophobic, microfibrous, polymeric web, wherein the surfaces of the microfibers making up the web are coated with a cured, precipitated, cationic, thermosetting binder resin or polymer. The filter sheet is further characterized by being hydrophilic and having a positive zeta potential.

Abstract: Filter media comprised of charge modified, resin coated inorganic microfibers are prepared by mixing inorganic microfibers with an aqueous solution of a water soluble, noncolloidal cationic thermosetting binder resin to form a dispersion, following which a precipitating agent is added to precipitate the binder resin and coat the microfibers. The coated microfibers may be used in the dispersed or suspended form as a filter aid. Preferably they are formed into a filter sheet which is then dried and cured to form a filter sheet of narrowly distributed pore size, pore sizes as small as one-half micron, and having a positive zeta potential in alkaline media. Glass is the preferred microfiber and polyamine-epichlorohydrins the preferred resins. By providing the normally negative zeta potential microfibers with a positive zeta potential the binder resins used to coat the microfibers substantially enhance particulate removal capabilities of the microfiber filter sheet.

Abstract: A process for cleaning porous metal filters, particularly stainless steel filters, comprising the steps of:(1) electrolyzing the filter in an electrolyte bath using the filter as one of the electrodes, preferably as the cathode of the electrolytic system, and subjecting the system to an imposed or applied current, highly preferably a DC current; and(2) rinsing the filter to remove electrolytic solution from the filter and flush any residual contaminants from the filter.When organic material is to be removed, a baking step prior to the electrolysis step is used.