Patents by Inventor Thomas C. J. Gribnau

Thomas C. J. Gribnau has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5294535
    Abstract: The invention concerns a method for detecting an analyte in a blood sample or a derived fraction thereof. In this method one uses the binding affinity between the analyte and its specific binding agent. Moreover, a reaction component containing a peroxidase label is added to the sample and specific binding agent to form a reaction mixture. The incubation of the reaction mixture, containing the analyte and its specific binding agent, with the peroxidase-labeled reaction component has to be carried out in the presence of a quaternary ammonium salt or ionic surfactant.
    Type: Grant
    Filed: September 14, 1992
    Date of Patent: March 15, 1994
    Assignee: Akzo N.V.
    Inventors: Thomas C. J. Gribnau, Leonardus P. C. Kuypers, Petrus A. L. Goossens
  • Patent number: 4373932
    Abstract: Processes, reagents and test kits for the qualitative and/or quantitative determination of an immunochemically reactive component, in which one or more labelled components are used, that are obtained by direct or indirect coupling of such a component or components to particles of an aqueous dispersion of a hydrophobic dye or pigment, or of polymer nuclei coated with such a dye or pigment.During the reaction or after an adequate reaction time the nature and/or the quantity of the dye is determined in the test medium, or optionally after a separation of the bound and free labelled components in one of the fractions.
    Type: Grant
    Filed: January 2, 1981
    Date of Patent: February 15, 1983
    Assignee: Akzona Incorporated
    Inventors: Thomas C. J. Gribnau, Frits Roeles, Johannes H. W. Leuvering