Patents by Inventor Thomas C. Pearson

Thomas C. Pearson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190213531
    Abstract: A method of supplying inventory includes sorting inventory into flexible inventory bags or soft-sided containers. Each flexible inventory bag or soft-sided container that receives the inventory corresponds with a final desired location in a building of a retailer. Each flexible inventory bag or soft-sided container is transported to the final desired location and inventory from the flexible inventory bag or soft-sided container is set into the final desired location.
    Type: Application
    Filed: December 10, 2018
    Publication date: July 11, 2019
    Inventors: Neal T. Anderson, Fatima H. Ayubi, Andrew T. Bean, Sukie C. Ewald, Amy E. Furfori, Terrence J. Hornsby, JR., Katherine E. Kelly, Thomas E. McMillan, Michael C. Pearson, Chris W. Prater, Neil Z. Witte
  • Patent number: 7829534
    Abstract: The present invention is a method of inhibiting islet cell transplant rejection particular, to treat diabetes, such as type-1 and type-2 diabetes, by administering to a subject an effective amount of a soluble CTLA4 mutant molecule. One example of soluble CTLA4 mutant molecule is L104EA29YIg.
    Type: Grant
    Filed: October 29, 2007
    Date of Patent: November 9, 2010
    Assignee: Bristol-Myers Squibb Company
    Inventors: Christian P. Larsen, Thomas C. Pearson, Andrew B. Adams, Robert J. Peach, Peter S. Linsley, Joseph Roy Naemura, Jurgen Bajorath
  • Publication number: 20090186037
    Abstract: The present invention provides a method for inhibiting an immune response and a method for inhibiting rejection of transplanted tissues. This method comprises preventing an endogenous molecule on a cell selected from the group consisting of gp39 and CD40 antigens from binding its endogenous ligand and preventing an endogenous molecule on a cell selected from the group consisting of CTLA4, CD28, and B7 antigens from binding its endogenous ligand. The prevention of such molecules from binding their ligand thereby blocks two independent signal pathways and inhibits the immune response resulting in transplanted tissue rejection.
    Type: Application
    Filed: September 10, 2008
    Publication date: July 23, 2009
    Inventors: Christian P. Larsen, Alejandro A. Aruffo, Diane L. Hollenbaugh, Peter S. Linsley, Jeffrey A. Ledbetter, Thomas C. Pearson
  • Publication number: 20080160022
    Abstract: The present invention is a method of inhibiting islet cell transplant rejection particular, to treat diabetes, such as type-1 and type-2 diabetes, by administering to a subject an effective amount of a soluble CTLA4 mutant molecule. One example of soluble CTLA4 mutant molecule is L104EA29YIg.
    Type: Application
    Filed: October 29, 2007
    Publication date: July 3, 2008
    Applicant: Bristol-Myers Squibb Company
    Inventors: Christian P. Larsen, Thomas C. Pearson, Andrew B. Adams, Robert J. Peach, Peter S. Linsley, Joseph Roy Naemura, Jurgen Bajorath
  • Patent number: 7304033
    Abstract: The present invention is a method of inhibiting islet cell transplant rejection, particularly to treat diabetes, such as type-1 and type-2 diabetes, by administering to a subject an effective amount of a soluble CTLA4 mutant molecule. One example of a soluble CTLA4 mutant molecule is L104EA29YIg.
    Type: Grant
    Filed: May 23, 2002
    Date of Patent: December 4, 2007
    Assignee: Bristol-Myers Squibb Company
    Inventors: Christian P. Larsen, Thomas C. Pearson, Andrew B. Adams, Robert J. Peach, Peter S. Linsley, Joseph Roy Naemura, Jurgen Bajorath
  • Patent number: 7024942
    Abstract: An apparatus and method for the non-destructive detection of pits and pit fragments found in dried fruit has been developed. It utilizes a force transducer and a signal processor to determine whether or not pit or pit fragments are present in a fruit specimen, and is able to automatically separate specimens testing positive from the product stream.
    Type: Grant
    Filed: May 10, 2004
    Date of Patent: April 11, 2006
    Assignee: The United States of America as represented by the Secretary of Agriculture
    Inventors: Eric S. Jackson, Ronald P. Haff, Thomas C. Pearson
  • Patent number: 6541725
    Abstract: An object, such as a pistachio nut, is sorted based on a given trait. The sorting process commences by bouncing the object off a body so that the object emits a sound. The sound emitted by the object is converted to an electrical signal which is analyzed to determine electrical characteristics that indicate the trait of the object. For example, the electrical signal can be integrated and a signal gradient produced to discriminate among signals from different classes of objects.
    Type: Grant
    Filed: April 3, 2001
    Date of Patent: April 1, 2003
    Assignee: The United States of America as represented by the Secretary of Agriculture
    Inventor: Thomas C. Pearson
  • Publication number: 20030022836
    Abstract: The present invention is a method of inhibiting islet cell transplant rejection particular, to treat diabetes, such as type-1 and type-2 diabetes, by administering to a subject an effective amount of a soluble CTLA4 mutant molecule. One example of soluble CTLA4 mutant molecule is L104EA29YIg.
    Type: Application
    Filed: May 23, 2002
    Publication date: January 30, 2003
    Inventors: Christian P. Larsen, Thomas C. Pearson, Andrew B. Adams
  • Publication number: 20030007968
    Abstract: Methods of establishing hematopoietic chimerism useful to correct hematological diseases and promote acceptance of organ transplants include administering busulfan, costimulation blockade, and readily attainable numbers of T-cell depleted bone marrow cells.
    Type: Application
    Filed: January 25, 2002
    Publication date: January 9, 2003
    Inventors: Christian P. Larsen, Thomas C. Pearson, Edmund K. Waller, Andrew B. Adams
  • Publication number: 20020139729
    Abstract: An object, such as a pistachio nut, is sorted based on a given trait. The sorting process commences by bouncing the object off a body so that the object emits a sound. The sound emitted by the object is converted to an electrical signal which is analyzed to determine electrical characteristics that indicate the trait of the object. For example, the electrical signal can be integrated and a signal gradient produced to discriminate among signals from different classes of objects.
    Type: Application
    Filed: April 3, 2001
    Publication date: October 3, 2002
    Inventor: Thomas C. Pearson
  • Publication number: 20020031510
    Abstract: The present invention provides a method for inhibiting an immune reponse and a method for inhibiting rejection of transplanted tissues. This method comprises preventing an endogenous molecule on a cell selected from the group consisting of gp39 and CD40 antigens from binding its endogenous ligand and preventing an endogenous molecule on a cell selected from the group consisting of CTLA4, CD28, and B7 antigens from binding its endogenous ligand. The prevention of such molecules from binding their ligand thereby blocks two independent signal pathways and inhibits the immune response resulting in transplanted tissue rejection.
    Type: Application
    Filed: May 22, 2001
    Publication date: March 14, 2002
    Applicant: Bristol-Myers Squibb Company
    Inventors: Christian P. Larsen, Alejandro A. Aruffo, Diane L. Hollenbaugh, Peter S. Linsley, Jeffrey A. Ledbetter, Thomas C. Pearson
  • Patent number: 5916560
    Abstract: The present invention provides a method for inhibiting an immune reponse and a method for inhibiting rejection of transplanted tissues. This method comprises preventing an endogenous molecule on a cell selected from the group consisting of gp39 and CD40 antigens from binding its endogenous ligand and preventing an endogenous molecule on a cell selected from the group consisting of CTLA4, CD28, and B7 antigens from binding its endogenous ligand. The prevention of such molecules from binding their ligand thereby blocks two independent signal pathways and inhibits the immune response resulting in transplanted tissue rejection.
    Type: Grant
    Filed: March 20, 1997
    Date of Patent: June 29, 1999
    Assignees: Bristol-Myers Squibb Company, Emory University
    Inventors: Christian P. Larsen, Alejandro A. Aruffo, Diane L. Hollenbaugh, Peter S. Linsley, Jeffrey A. Ledbetter, Thomas C. Pearson
  • Patent number: 5703784
    Abstract: An object is sorted into different classes by producing a video image of the object. The signal level discontinuities in the image are evaluated by first deriving a video signal gradient of each pixel in the image. Then the number of pixels in three different signal gradient ranges are counted to produce count parameters which combined indicate the areas of differing contrast in the object. The count parameters are utilized in a pair of discriminate functions which define the two classes and solution of the discriminate functions are used to determine the probability that the object fits within one class. In response to the probability the object is directed along either a first path associated with one class or along a second path associated with the other class.
    Type: Grant
    Filed: October 30, 1995
    Date of Patent: December 30, 1997
    Assignee: The United States of America as represented by the Secretary of Agriculture
    Inventor: Thomas C. Pearson