Abstract: A novel, mechanical method and apparatus for scraping desired solids from the interior walls of various vessels, especially spherical glass or metal flasks common to chemical laboratory settings is described. The present invention utilizes spinning, flexible, abrasive tentacles fixed to a vertical shaft. The rotary motion of the vertical shaft is driven by a simple electrical or pneumatic motor. Centrifugal force extends the tentacles, which act as brushes, whereby their abrasive contact with the solids caked to the interior walls effects mechanical scraping. While spinning, the apparatus is moved vertically up and down to effect complete scraping. The present invention, therefore, rapidly removes the majority of dry solid material stuck to the interior of a spherical vessel with a minimum of physical effort. This method provides a significant improvement over the existing standard practice of slow, uncomfortable, manual scraping with spatulas.

Abstract: A novel method for testing if smoking has occurred within a space. Smoking is determined to have happened by testing for and confirming the presence of nicotine using a lateral flow test strip. The nicotine may be captured from secondhand smoke by exposing the condensing pad of the lateral flow tester to air within the space prior to activating the test strip. The nicotine may also be captured as part of thirdhand smoke residue on a surface within the space. A prior art commercially available lateral flow test strip used to test for the presence of cotinine within a biological sample, is used in novel ways for detecting for the past presence of nicotine smoke within a space. Improvements to the test apparatus are also disclosed.

Abstract: Non-steroidal tricyclic quinolinone and tricyclic quinoline compounds and compositions that are agonists, partial agonists and/or antagonists for androgen receptors (AR), their preparation and their uses are described.

Abstract: Compounds, pharmaceutical compositions, and methods for modulating processes mediated by steroid receptors. In particular, preparation and methods of use of non-steroidal compounds and compositions that are agonists, partial agonists, and antagonists for the androgen receptor (AR) are described. Further, described are the methods of making and use of critical intermediates including a stereoselective synthetic route to intermediates for the AR modulators.

Abstract: Non-steroidal tricyclic quinolinone and tricyclic quinoline compounds and compositions that are agonists, partial agonists and/or antagonists for androgen receptors (AR), their preparation and their uses are described.

Abstract: The present invention relates to thienopyrmidine compounds of formula (I) (one of A1 and A2 is S and the other is CH), salts thereof, as well as use and preparation of the same. These compounds are inhibitors of various protein tyrosine kinases (PTKs) of the ErbB family and consequently are useful in the treatment of disorders mediated by aberrant activity of such kinases.