Patents by Inventor Thomas Cappola

Thomas Cappola has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for diagnosing heart failure and other cardiac diseases
    Patent number: 8962257
    Abstract: The invention relates to methods of diagnosing the severity of heart failure or a cardiac dysfunction in a subject. The invention further relates to monitoring the severity of heart failure in a subject and determining the prognosis of a subject that has suffered from heart failure. This invention also relates methods to identify patients at risk for cardiac dysfunction when exposed to cardiotoxic chemotherapy agents.
    Type: Grant
    Filed: March 8, 2011
    Date of Patent: February 24, 2015
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Bonnie Ky, Thomas Cappola, Douglas B. Sawyer
  • Predictors of transplant rejection determined by peripheral blood gene-expression profiling
    Patent number: 8053182
    Abstract: The present invention provides methods and kits for predicting transplant rejection or tolerance. Methods for predicting the probability of cardiac allograft rejection via profiling of peripheral blood gene expression are also provided.
    Type: Grant
    Filed: January 31, 2005
    Date of Patent: November 8, 2011
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Thomas Cappola, Jonathan A. Epstein
  • METHODS FOR DIAGNOSING HEART FAILURE AND OTHER CARDIAC DISEASES
    Publication number: 20110256562
    Abstract: The invention relates to methods of diagnosing the severity of heart failure or a cardiac dysfunction in a subject. The invention further relates to monitoring the severity of heart failure in a subject and determining the prognosis of a subject that has suffered from heart failure. This invention also relates methods to identify patients at risk for cardiac dysfunction when exposed to cardiotoxic chemotherapy agents.
    Type: Application
    Filed: March 8, 2011
    Publication date: October 20, 2011
    Inventors: Bonnie Ky, Thomas Cappola, Douglas B. Sawyer
  • Novel Predictors of Transplant Rejection Determined by Peripheral Blood Gene-Expression Profiling
    Publication number: 20080274906
    Abstract: The present invention provides methods and kits for predicting transplant rejection or tolerance. Methods for predicting the probability of cardiac allograft rejection via profiling of peripheral blood gene expression are also provided.
    Type: Application
    Filed: August 18, 2005
    Publication date: November 6, 2008
    Inventors: Thomas Cappola, Jonathan A. Epstein