Abstract: In various embodiments methods and compositions for improving a recovery of a subject after a cerebral ischemic injury, such as white matter stroke are provided. In certain embodiments, the methods involve administering human induced pluripotent glial enriched progenitor cells into the brain of the subject.

Abstract: A therapeutic hydrogel material includes a hyaluronic acid-based hydrogel matrix containing naked heparin nanoparticles distributed and entrained within the matrix. The naked heparin nanoparticles contained in the matrix are not immobilized to any other molecules at the time of delivery. In one aspect of the invention, the therapeutic hydrogel material is used to repair ischemic tissue in a subject (e.g., mammal). The therapeutic hydrogel material may also be used to treat wounds or other damaged tissue. To treat the subject or patient, the site of application is located and the therapeutic hydrogel material is injected or otherwise delivered (with or without a delivery device) to the delivery location along with a crosslinker.

Abstract: In various embodiments methods and compositions for improving a recovery of a subject after a cerebral ischemic injury, such as white matter stroke are provided. In certain embodiments, the methods involve administering human induced pluripotent glial enriched progenitor cells into the brain of the subject.

Abstract: A supporting frame for supporting decorative materials to be formed into a wreath or the like, comprises a frame member, preferably ring-shaped, having a first substantially horizontal portion which is provided with means for retention of the decorative material and prevention of its movement in the plane of the ring-shaped member after the material has been fastened thereto. A second vertical portion of the ring member forms a lip extending along the outer periphery of the first horizontal portion and is designed to increase the strength of the frame and prevent the decorative materials from rolling off the face of the ring-shaped member.

Abstract: An apparatus for manufacturing a wreath from a plurality of elongated objects, such as boughs by securing the boughs to a frame with a securing member such as a wire.