Abstract: Provided herein are, among other things, methods for treating a patient suffering from a CD38+ cancer.

Abstract: The present disclosure relates to indolinyl compounds. The present disclosure further relates to compounds that inhibit viral helicase-primase. The present disclosure further relates to the use of the compounds for the preparation a medicament for the treatment of diseases and/or condition through inhibiting viral helicase-primase. The present disclosure also relates to use of those compounds in the treatment of viral infections. The present disclosure further relates to intermediates for its preparation and to pharmaceutical compositions containing those compounds.

Abstract: According to some embodiments, a point of care salivary testing device comprises a biofluid collection device, a cartridge device, a reader device, and/or a software-based detection interface system. The analyte detection system may be used to detect the presence and/or quantity of one or more target analytes.

Abstract: Embodiments described herein include electronic packages and methods of forming such packages. An electronic package includes a package substrate, first conductive pads formed over the package substrate, where the first conductive pads have a first surface area, and second conductive pads over the package substrate, where the second conductive pads have a second surface area greater than the first surface area. The electronic package also includes a solder resist layer over the first and second conductive pads, and a plurality of solder resist openings that expose one of the first or second conductive pads. The solder resist openings of the electronic package may include conductive material that is substantially coplanar with a top surface of the solder resist layer. The electronic package further includes solder bumps over the conductive material in the solder resist openings, where the solder bumps have a low bump thickness variation (BTV).

Abstract: An augmented reality-based lighting design method includes displaying, by an augmented reality device, a real-time image of a target physical area on a display screen. The method further includes displaying, by the augmented reality device, a lighting fixture 3-D model on the display screen in response to a user input, where the lighting fixture 3-D model is overlaid on the real-time image of the target physical area. The method also includes displaying, by the augmented reality device, a lighting pattern on the display screen overlaid on the real-time image of the target physical area, wherein the lighting pattern is generated based on at least photometric data associated with the lighting fixture 3-D model.

Abstract: A vehicle door assembly comprises an inner door panel, an outer door panel and a mirror assembly. The outer panel is fixed to the inner door panel, the outer door panel having an mounting opening. The mirror assembly is supported to an outer perimeter of the mounting opening of the outer door panel. The mirror assembly has a base bracket and a dampener. The dampener is disposed between the base bracket and at least a portion of the outer perimeter mounting opening of the outer door panel such that the base bracket and the outer door panel are spaced with respect to each other by the dampener.

Abstract: The present disclosure describes a vehicle console that includes: a housing defining an inner chamber; a panel that is movable in relation to the housing such that the vehicle console is reconfigurable between a first configuration and a second configuration; and an actuation assembly including a scissor lift that is connected to the panel to facilitate reconfiguration of the vehicle console between the first configuration and the second configuration. When the vehicle console is in the first configuration, the panel is generally flush with an outer surface of the housing, and when the vehicle console is in the second configuration, the panel is recessed into the housing so as to define a storage compartment that is configured to receive a personal article.

Abstract: A light pipe for a vehicle lamp assembly includes a first pipe portion and a second pipe portion. The first pipe portion has a first section that extends between a first end and a second end. A portion of the first section at least partially defines an intersection area. The first pipe portion defines a first optical path extending in a lengthwise direction of the first pipe portion. The second pipe portion has a second section that extends through the intersection area. The second pipe portion defines a second optical path. The second optical path intersects with and extends through the first optical path of the first pipe portion such that the first section and the second section define an angle greater than zero degrees and less than 180 degrees therebetween. The first pipe portion and the second pipe portion a unitarily formed as a single monolithic element.

Abstract: A light pipe for a vehicle lamp assembly includes a first pipe portion and a second pipe portion. The first pipe portion has a first section that extends between a first end and a second end. A portion of the first section at least partially defines an intersection area. The first pipe portion defines a first optical path extending in a lengthwise direction of the first pipe portion. The second pipe portion has a second section that extends through the intersection area. The second pipe portion defines a second optical path. The second optical path intersects with and extends through the first optical path of the first pipe portion such that the first section and the second section define an angle greater than zero degrees and less than 180 degrees therebetween. The first pipe portion and the second pipe portion a unitarily formed as a single monolithic element.

Abstract: A first lamp assembly has a first attachment surface, a first transparent surface, a first side surface extending from the first transparent surface to the first attachment surface, and a first lighting member positioned to emit light through a portion of the first side surface. A second lamp assembly has a second attachment surface, a second transparent surface opposite the second attachment surface and a second side surface extending from the second transparent surface to the second attachment surface. The second side surface has a first projection extending therefrom that defines a first light deflecting surface such that when the second side surface and the first side surface are adjacent to one another with the light deflecting surface and first lighting member being aligned, the first light deflecting surface reflects and disperses light in a first area between the first lamp assembly and the second lamp assembly.

Abstract: An amplifier circuit is provided. The amplifier circuit includes an amplifier stage; a plurality of variable transistors connected to the amplifier stage; a transconductor connected to at least one of the plurality of variable transistors; and a hybrid differential envelope detector and full-wave rectifier connected to the transconductor.

Abstract: A first lamp assembly has a first attachment surface, a first transparent surface, a first side surface extending from the first transparent surface to the first attachment surface, and a first lighting member positioned to emit light through a portion of the first side surface. A second lamp assembly has a second attachment surface, a second transparent surface opposite the second attachment surface and a second side surface extending from the second transparent surface to the second attachment surface. The second side surface has a first projection extending therefrom that defines a first light deflecting surface such that when the second side surface and the first side surface are adjacent to one another with the light deflecting surface and first lighting member being aligned, the first light deflecting surface reflects and disperses light in a first area between the first lamp assembly and the second lamp assembly.

Abstract: An amplifier circuit is provided. The amplifier circuit includes an amplifier stage; a plurality of variable transistors connected to the amplifier stage; a transconductor connected to at least one of the plurality of variable transistors; and a hybrid differential envelope detector and full-wave rectifier connected to the transconductor.

Abstract: A dynamically biased baseband current amplifier is provided. The dynamically biased baseband current amplifier includes an input interface; a controller; a variable resistor network; an amplifier stage; a hybrid differential envelope detector and full-wave rectifier; a transconductor; a first variable transistor; a second variable transistor; a third variable transistor; and a fourth variable transistor.

Abstract: The present disclosure provides a method and a phase lock detection apparatus for detecting whether a phase of an output signal is locked to the phase of a reference signal. The apparatus includes a first divider that individually frequency-divides first and second pulse signals, a phase frequency detector that outputs third and fourth pulse signals that correspond to a phase difference between the frequency-divided first and second pulse signals, a second divider that individually frequency-divides the third and fourth pulse signals, and a determiner that determines whether a phase of the second pulse signal is locked, based on the frequency-divided third and fourth pulse signals.

Abstract: A first and second hybrid envelope detector and full-wave rectifier is provided. The first hybrid envelope detector and full-wave rectifier includes a first P-channel Field Effect Transistor (PFET); a second PFET; a first N-channel Field Effect Transistor (NFET); a second NFET; a third NFET; a fourth NFET; a fifth NFET; a controller; a variable transistor; and a variable capacitor. The second hybrid envelope detector and full-wave rectifier includes a first N-channel Field Effect Transistor (NFET); a second NFET; a first P-channel Field Effect Transistor (PFET); a second PFET; a third PFET; a fourth PFET; a fifth PFET; a controller; a variable transistor; and a variable capacitor.

Abstract: A first and second hybrid envelope detector and full-wave rectifier is provided. The first hybrid envelope detector and full-wave rectifier includes a first P-channel Field Effect Transistor (PFET); a second PFET; a first N-channel Field Effect Transistor (NFET); a second NFET; a third NFET; a fourth NFET; a fifth NFET; a controller; a variable transistor; and a variable capacitor. The second hybrid envelope detector and full-wave rectifier includes a first N-channel Field Effect Transistor (NFET); a second NFET; a first P-channel Field Effect Transistor (PFET); a second PFET; a third PFET; a fourth PFET; a fifth PFET; a controller; a variable transistor; and a variable capacitor.

Abstract: A dynamically biased baseband current amplifier is provided. The dynamically biased baseband current amplifier includes an input interface; a controller; a variable resistor network; an amplifier stage; a hybrid differential envelope detector and full-wave rectifier; a transconductor; a first variable transistor; a second variable transistor; a third variable transistor; and a fourth variable transistor.

Abstract: A wireless telecommunication system that automatically enforces a quiet mode of operation for a wireless handset comprises a cellular telecommunication network, and a wireless handset configured to transmit voice and data information to, and configured to receive voice and data information from the cellular telecommunication network. The wireless handset comprises a quiet mode controller configured to disable the wireless handset from issuing the audible notification when the wireless handset is in a designated quiet zone location.

Abstract: A wireless telecommunication system that automatically enforces a quiet time mode of operation for a wireless handset comprises a cellular telecommunication network, and a wireless handset configured to transmit voice and data information to, and configured to receive voice and data information from the cellular telecommunication network. The wireless handset comprises a quiet time controller configured to disable the wireless handset from issuing the audible notification during scheduled quiet time periods.