Abstract: A cosmetic container may include a base assembly including an open top and a closed bottom, and a cap configured to be removably coupled to the base assembly. The base assembly may include a helical slot on an inner surface. The cosmetic container may include a shell configured to fit within the base assembly, and a cup configured to fit within the shell. The cup may be configured to engage with the helical slot to move up and down within the cosmetic container. The cup may be configured for holding a cosmetic product stick. The base assembly, the shell, the cup and the cap may be formed from a same eco-friendly material.

Abstract: A cosmetic container may include a base assembly including an open top and a closed bottom, and a cap configured to be removably coupled to the base assembly. The base assembly may include a helical slot on an inner surface. The cosmetic container may include a shell configured to fit within the base assembly, and a cup configured to fit within the shell. The cup may be configured to engage with the helical slot to move up and down within the cosmetic container. The cup may be configured for holding a cosmetic product stick. The base assembly, the shell, the cup and the cap may be formed from a same eco-friendly material.

Abstract: A cosmetic container includes a base, a lid, and a cover. The base defines at least one well for holding a cosmetic, and a base cavity on an opposite surface as the well, and the lid defines a lid cavity. The cover couples the lid to the base, the cover includes a top portion disposed within the lid cavity and a bottom portion disposed within the base cavity. The cover forms a hinge allowing the lid to rotate relative to the base from a closed position in which the first surface of the lid is disposed over the well in the base, to an open position in which the well is exposed. The cover has a flexibility different from the base and lid.

Abstract: An automatic injection syringe that is pre-loaded with medicament and protected from inadvertent ejection of said medicament or injection of air. A plunger assembly is first positioned with a compressed spring in between a plunger and a retainer element. The compressed spring is held in place by a resilient retainer sleeve and the plunger is inside the syringe tube. When the syringe is pushed back, the resilient retainer sleeve releases the spring which then expands to push the plunger into the reservoir of the syringe tube to eject the medicament out from a syringe needle.

Abstract: An arrangement for covering the sharp point of a needle of a syringe or similar needle device. The arrangement includes a hollow cover which exposes the needle in a retracted position and covers the needle in the deployed condition. A resilient multi-section link anchored to the syringe may propel the hollow cover to the deployed position when the link or the needle device is pressed against an environmental surface. The arrangement may be integral with the needle device or may be formed as a separate component which is attachable to the needle device. An optional cap may cover the needle when the hollow cover is in the retracted position.

Abstract: Protection for the otherwise exposed sharp point of a needle of an injection device. A two part cover for the needle comprises a stationary base which engages the injection device, and a relatively movable cover. The cover is guided to slide longitudinally along the base by a groove-and-projection system. The projection is held in an initial position, and slides along the groove during injection. At the end of the injection, the projection is immobilized in the groove at a final position, and immobilizes the moveable cover in a deployed position covering the needle.

Abstract: A locating guide for locating a target tissue site within a patient includes a body, a first substantially radiopaque reference marker on the body, and a second substantially radiopaque reference marker extending from a major surface of the body. The reference markers provide reference points that extend in at least two dimensions, and may be useful for registering a medical image of tissue with an actual location on or within the patient in order to more accurately and precisely locate a target tissue site within the patient. In some embodiments, the second reference marker is oriented at a predetermined angle relative to the major surface of the body, and provides a guide that a clinician may reference in order to orient a medical element introducer when introducing the introducer into the patient to access a particular target tissue site.

Abstract: A guard for the sharp tip of a needle of an injection syringe. The guard may comprise two components which are separate from and readily attachable to the syringe. One component is stationary and the other movable relative to the syringe. The movable member moves by expanding longitudinally to cover the otherwise exposed needle tip when the plunger of the syringe is depressed beyond a predetermined degree. The stationary member releasably holds the movable member in the initial position, and releases the movable member to expand and thus deploy when the predetermined degree of depression is imposed by the user of the syringe.

Abstract: A self-deploying cover for protection against unintended pricks from injection devices. The cover comprises a base which engages the injection device, and a protective sleeve which covers the sharp point and moves relative to the base to expose and cover the sharp point. The sleeve is guided by a projection which rides within a generally V-shaped groove formed in the base. The groove comprises deflectable arms which deflect to pass the projection, but which oppose return of the projection after passing. The sleeve is spring urged to the extended position and is automatically withdrawn during injections. After an injection, the sleeve is locked into the extended position by the last deflectable arm.

Abstract: Protection for the otherwise exposed sharp point of a needle of an injection device. A two part cover for the needle comprises a stationary base which engages the injection device, and a relatively movable cover. The cover is guided to slide longitudinally along the base by a groove-and-projection system. The projection is held in an initial position, and slides along the groove during injection. At the end of the injection, the projection is immobilized in the groove at a final position, and immobilizes the moveable cover in a deployed position covering the needle.

Abstract: An injection device such as a syringe, which has a helical flow path for a solution in which the solvent and solute have been introduced. The helical flow path is formed by a helically configured member which has general overall configuration of a helical coil spring. Individual coils may be formed to have a groove located along the length of the helix. When compressed, the novel member effectively takes on a cylindrical outer configuration. Because the groove is covered and sealed by the surface of the next turn of the helix when compressed, an enclosed helical flow path is formed in the compressed member. The invention may be an injection device using the novel flow path forming member or alternatively, the flow path forming member itself.

Abstract: An apparatus for applying medicament delivery pressure to a plunger pad of a plunger of a syringe includes a spring having a first end and a second end, wherein the spring first end is operable to abut the plunger pad. The assembly also includes a shell including an interior and a first step therein. A cap is disposed within the shell interior. The cap includes a surface for engaging the spring second end. The cap is movable from a first position, wherein the shell first step retains the cap in releasable engagement with the plunger such that the spring is compressed between the cap surface and plunger pad, and a second position, wherein the cap disengages the shell first step such that the cap disengages the plunger such that the spring expands to move the barrel and needle forward as well as deliver medicament delivery pressure to the plunger pad.

Abstract: An apparatus for actuating a syringe. The syringe includes a barrel, a plunger and a needle. A needle shield is near the front of the barrel and is movable from a first position enclosing the needle and a retracted position wherein the needle is exposed. A spring abuts the plunger. A cap has an interior wall for engaging the spring and releasably engages the plunger. The spring is compressed between the plunger and the interior wall when the cap releasably engages the plunger. A resilient member releasably secures the cap in releasable engagement with the plunger and is movable from a first position to a compressed position when the needle shield is moved from its first position to its retracted position. The cap disengages the plunger when the resilient member is moved to the compressed position wherein the spring expands to provide a medicament delivery pressure to the plunger.

Abstract: An injection device such as a syringe, which has a helical flow path for a solution in which the solvent and solute have been introduced. The helical flow path is formed by a helically configured member which has general overall configuration of a helical coil spring. Individual coils may be formed to have a groove located along the length of the helix. When compressed, the novel member effectively takes on a cylindrical outer configuration. Because the groove is covered and sealed by the surface of the next turn of the helix when compressed, an enclosed helical flow path is formed in the compressed member. The invention may be an injection device using the novel flow path forming member or alternatively, the flow path forming member itself.

Abstract: An auto-injector that includes a hollow tubular shell to retain the internal structure and provide a surface to be held by the user; a trigger for activating the auto-injector; a plunger lock for slideably inserting into the trigger and for retaining a plunger in the operative position prior to use; and, a syringe assembly comprising a hollow tubular barrel for slideably receiving the plunger, such that when the trigger is activated the syringe assembly is activated and the injection is automatically administered.

Abstract: Cable managers of the present invention include a panel, at least two adjacent spaced-apart projections, which define an opening therebetween, and a tab connected to at least one of the projections. The tab assists in cable routing and retention. In one embodiment, the tab extends to a distance at least midway between a top surface of the one projection and the bottom surface of the other projection. In another embodiment, a distance between a top surface of the tab on one projection and the bottom surface of another adjacent projection is between about 0.10 inches and about 0.30 inches. In yet another embodiment, a cable manager comprises separable portions, and at least one spacer member which is adapted to be attached to each of separable first and second portions. The spacer member increases the width of the manager to provide additional space to run cable within the manager.

Abstract: A safety syringe that includes syringe assembly retained within a hollow tubular shell, whereby a retaining member is utilized for retaining the syringe assembly in an operative position such that it is available for administering a shot. After the safety syringe is used, a retracting assembly retracts the syringe assembly into the shell and locks it in place thereby preventing any accidental pricks.

Abstract: A locating guide for locating a target tissue site within a patient includes a body, a first substantially radiopaque reference marker on the body, and a second substantially radiopaque reference marker extending from a major surface of the body. The reference markers provide reference points that extend in at least two dimensions, and may be useful for registering a medical image of tissue with an actual location on or within the patient in order to more accurately and precisely locate a target tissue site within the patient. In some embodiments, the second reference marker is oriented at a predetermined angle relative to the major surface of the body, and provides a guide that a clinician may reference in order to orient a medical element introducer when introducing the introducer into the patient to access a particular target tissue site.

Abstract: The present invention relates to inducible gene expression constructs and methods of inducing gene expression using a combination of inducing agents.

Abstract: Oral progesterone unit dosage forms comprising micronized progesterone and a solid polymeric carrier are provided. The dosage forms, upon oral administration, provide a therapeutically effective blood level of progesterone to a subject. The therapeutically effective blood level of progesterone may range from about 0.1 ng/ml to about 400 ng/ml. The dosage forms can be prepared for immediate as well as sustained release. The oral progesterone dosage form can be combined with an estrogen dosage form to provide combination hormone therapy.