Patents by Inventor Thomas Ciaran Loughman

Thomas Ciaran Loughman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS FOR THE SUSTAINED RELEASE OF SOMATOSTATIN ANALOGS
    Publication number: 20190167754
    Abstract: Process for the preparation of an injectable pharmaceutical composition for the sustained release of somatostatin analogues. Composition prepared according to such a process.
    Type: Application
    Filed: December 26, 2018
    Publication date: June 6, 2019
    Applicant: IPSEN PHARMA S.A.S.
    Inventors: Martin MONTES, Thomas Ciaran Loughman, Chantal Roume, Roland Cherif-Cheikh
  • Process for the preparation of pharmaceutical compositions for the sustained release of somatostatin analogs
    Patent number: 10206968
    Abstract: A process for the preparation of injectable pharmaceutical compositions for the sustained release of somatostatin analogs and compositions prepared according to the process. The process may comprise lyophilizing a mixture of lanreotide acetate and acetic acid to form a lyophilizate and hydrating the lyophilizate, wherein the lyophilization is performed only once.
    Type: Grant
    Filed: April 27, 2016
    Date of Patent: February 19, 2019
    Assignee: IPSEN PHARMA S.A.S.
    Inventors: Martin Montes, Thomas Ciaran Loughman, Chantal Roume, Roland Cherif-Cheikh
  • PROCESS FOR THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS FOR THE SUSTAINED RELEASE OF SOMATOSTATIN ANALOGS
    Publication number: 20160339075
    Abstract: A process for the preparation of injectable pharmaceutical compositions for the sustained release of somatostatin analogues and compositions prepared according to the process. The process may comprise lyophilizing a mixture of lanreotide acetate and acetic acid to form a lyophilizate and hydrating the lyophilizate, wherein the lyophilization is performed only once.
    Type: Application
    Filed: April 27, 2016
    Publication date: November 24, 2016
    Inventors: Martin MONTES, Thomas Ciaran LOUGHMAN, Chantal ROUME, Roland CHERIF-CHEIKH
  • Process for the preparation of pharmaceutical compositions for the sustained release of somatostatin analogs
    Patent number: 9352012
    Abstract: The invention relates to a process for the preparation of injectable pharmaceutical compositions for the sustained release of somatostatin analogues and to pharmaceutical compositions prepared according to the process. In a preferred aspect the process comprises the steps of combining lanreotide acetate and acetic acid, lyophilizing the resulting mixture only once, and hydrating the lyophilizate. Acetic acid may be added to a desired pH during the final step of the process.
    Type: Grant
    Filed: January 11, 2011
    Date of Patent: May 31, 2016
    Assignee: IPSEN PHARMA S.A.S.
    Inventors: Martin Montes, Thomas Ciaran Loughman, Chantal Roume, Roland Cherif-Cheikh
  • Transdermal Administration Of Peptides
    Publication number: 20130085105
    Abstract: The present invention relates to a method of increasing the bioavailability of a peptide. The method includes altering the lipophilicity of a peptide by the creation of fatty acid peptide salts of the peptide. The fatty acid peptide salts exhibit increased transdermal and transmucosal permeability.
    Type: Application
    Filed: March 23, 2011
    Publication date: April 4, 2013
    Applicants: The Provost, Fellows and Scholars of the College of Holy Trinity and Undivided Trinity of Queen Eli, Ipsen Manufacturing Ireland Limited
    Inventors: Patrick Bernard Deasy, Thomas Ciaran Loughman
  • PROCESS FOR THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS FOR THE SUSTAINED RELEASE OF SOMATOSTATIN ANALOGS
    Publication number: 20130079282
    Abstract: The invention relates to a process for the preparation of injectable pharmaceutical compositions for the sustained release of somatostatin analogues and to pharmaceutical compositions prepared according to the process. In a preferred aspect the process comprises the steps of combining lanreotide acetate and acetic acid, lyophilizing the resulting mixture only once, and hydrating the lyophilizate. Acetic acid may be added to a desired pH during the final step of the process.
    Type: Application
    Filed: January 11, 2011
    Publication date: March 28, 2013
    Applicant: Ipsen Pharma S.A.S.
    Inventors: Martin Montes, Thomas Ciaran Loughman, Chantal Roume, Roland Cherif-Cheikh
  • PROCESS FOR THE SYNTHESIS OF (AIB8,35)HGLP-1(7-36)-NH2
    Publication number: 20130030148
    Abstract: The present invention relates to a process for the large-scale synthesis of (Aib8,35)hGLP-1(7-36)-NH2 (SEQ ED NO:2), i.e., His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gb-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Aib-Arg-NH2 (SEQ ID NO:2), which comprises solid-phase Fmoc-chemistry.
    Type: Application
    Filed: September 22, 2009
    Publication date: January 31, 2013
    Inventors: Zheng Xin Dong, Thomas Ciaran Loughman, Fionn Hurley, Steven R. Johnson
  • Sustained release ionic conjugate
    Patent number: 7179490
    Abstract: A method of spherifying a sustained release ionic conjugate which contains a free carboxyl group-containing biodegradable polymer and a free amino group-containing drug which are ionically bonded to each other.
    Type: Grant
    Filed: January 19, 2006
    Date of Patent: February 20, 2007
    Assignee: Ipsen Manufacturing Ireland Limited
    Inventors: Francis Xavier Ignatious, Thomas Ciaran Loughman, Shalaby Wahba Shalaby, Franck Jean-Claude Touraud
  • Sustained release ionic conjugate
    Patent number: 7026431
    Abstract: A method of spherifying a sustained release ionic conjugate which contains a free carboxyl group-containing biodegradable polymer and a free amino group-containing drug which are ionically bonded to each other.
    Type: Grant
    Filed: August 7, 2003
    Date of Patent: April 11, 2006
    Assignee: Ipsen Manufacturing Ireland Limited
    Inventors: Francis Xavier Ignatious, Thomas Ciaran Loughman, Shalaby Wahba Shalaby, Franck Jean-Claude Touraud
  • Sustained release ionic conjugate
    Patent number: 6911218
    Abstract: A method of spherifying a sustained release ionic conjugate which contains a free carboxyl group-containing biodegradable polymer and a free amino group-containing drug which are ionically bonded to each other.
    Type: Grant
    Filed: April 22, 1997
    Date of Patent: June 28, 2005
    Assignee: Ipsen Manufacturing Ireland Limited
    Inventors: Francis Xavier Ignatious, Thomas Ciaran Loughman, Shalaby Wahba Shalaby, Franck Jean-Claude Touraud
  • Process to make a sustained release formulation
    Patent number: 6893645
    Abstract: This invention pertains to a process for making a sustained release complex. Compound (I), which comprises Compound (A), having formula (A), and a copolymer comprising poly (l)-lactic-glycolic-tartaric acid (P(I)LGT), wherein the amino group of Compound (A) is ionically bound to a carboxyl group of the (P(I)LGT).
    Type: Grant
    Filed: August 14, 2000
    Date of Patent: May 17, 2005
    Assignee: Ipsen Manufacturing Ireland Limited
    Inventor: Thomas Ciarán Loughman
  • Process for making absorbable microparticles
    Patent number: 6555156
    Abstract: The invention pertains to a process for making encased bound microparticles by nebulizing a dispersion of the bound microparticles into a solution of an encasing polymer and into a liquid, non-solvent of said encasing polymer.
    Type: Grant
    Filed: July 26, 2000
    Date of Patent: April 29, 2003
    Assignee: Kinerton Limited
    Inventor: Thomas Ciaran Loughman
  • SUSTAINED RELEASE IONIC CONJUGATE
    Publication number: 20020041893
    Abstract: A method of spherifying a sustained release ionic conjugate which contains a free carboxyl group-containing biodegradable polymer and a free amino group-containing drug which are ionically bonded to each other.
    Type: Application
    Filed: April 20, 1999
    Publication date: April 11, 2002
    Inventors: FRANCIS XAVIER IGNATIOUS, THOMAS CIARAN LOUGHMAN, SHALABY WAHBA SHALABY, FRANCK-JEAN-CLAUDE TOURAUD
  • Acidic polylactic polymers
    Patent number: 6111033
    Abstract: A biodegradable polyester prepared from lactic acid, and, optionally, other hydroxy acid or acids. The polyester contains 4-100 carboxyl groups and has an average molecular weight of 1,000 to 200,000 g/mol. Also disclosed are methods of making such polyesters.
    Type: Grant
    Filed: January 15, 1999
    Date of Patent: August 29, 2000
    Assignee: Kinerton, Limited
    Inventors: Thomas Ciaran Loughman, Ruth Mary Russell, Franck Jean-Claude Touraud