Abstract: A method includes receiving, with a processor in communication with a first exercise machine, a first request for an exercise class, the first request being provided by a first user of the first exercise machine. The method also includes providing a video file associated with the exercise class to the first exercise machine, providing a notification to a second user indicating that the first user has chosen to participate in the exercise class, and receiving a second request for the exercise class provided by the second user. The method further includes providing the video file to a second exercise machine of the second user via the network. In such a method, display of the video file via a display of the second exercise machine is synchronized with display of the video file via a display of the first exercise machine.

Abstract: Media hub systems and methods for providing content for display on a device provided. The media system may include a hub and a mount configured to secure the hub to a plurality of structures. The hub may include a camera and be configured to provide content for display on a device. The mount may be configured to couple to the hub via a magnetic connection. The magnetic connection may be configured to allow the hub to tilt relative to the mount to adjust a field-of-view of the camera.

Abstract: A method includes receiving, with a processor in communication with a first exercise machine, a first request for an exercise class, the first request being provided by a first user of the first exercise machine. The method also includes providing a video file associated with the exercise class to the first exercise machine, providing a notification to a second user indicating that the first user has chosen to participate in the exercise class, and receiving a second request for the exercise class provided by the second user. The method further includes providing the video file to a second exercise machine of the second user via the network. In such a method, display of the video file via a display of the second exercise machine is synchronized with display of the video file via a display of the first exercise machine.

Abstract: A method includes receiving, with a processor in communication with a first exercise machine, a first request for an exercise class, the first request being provided by a first user of the first exercise machine. The method also includes providing a video file associated with the exercise class to the first exercise machine, providing a notification to a second user indicating that the first user has chosen to participate in the exercise class, and receiving a second request for the exercise class provided by the second user. The method further includes providing the video file to a second exercise machine of the second user via the network. In such a method, display of the video file via a display of the second exercise machine is synchronized with display of the video file via a display of the first exercise machine.

Abstract: Media hub systems and methods for providing content for display on a device provided. The media system may include a hub and a mount configured to secure the hub to a plurality of structures. The hub may include a camera and be configured to provide content for display on a device. The mount may be configured to couple to the hub via a magnetic connection. The magnetic connection may be configured to allow the hub to tilt relative to the mount to adjust a field-of-view of the camera.

Abstract: The invention relates to a pharmaceutical composition containing a PLP-dependent enzyme and optionally its cofactor, pyridoxal phosphate (PLP), and/or a phosphate or non-phosphate precursor of PLP, its use as a drug, its production method and a therapeutic treatment method related to it. The pharmaceutical composition comprises erythrocytes and a pharmaceutically acceptable vehicle, the erythrocytes encapsulating the PLP-dependent enzyme. The PLP-dependent enzyme may be methioninase, tyrosine phenol-lyase, tyrosine aminotransferase or cystathionine beta-synthase.

Abstract: An exercise machine includes a processor, a first display, a deck, and a belt rotatable about the deck. The machine also includes a sensor operably connected to the processor and configured to detect a first performance parameter of a first user running on the belt of the exercise machine. The processor is configured to receive information indicative of a second performance parameter of a second user, the second performance parameter being detected at an additional exercise machine during display of the at least part of the exercise class on a display associated with the additional exercise machine. The processor is also configured to cause the second performance parameter to be displayed on the first display together with the first performance parameter.

Abstract: A method includes receiving a video input, receiving an indication of a first segment type corresponding to a first workout activity being performed in the video input, and generating a segmented timeline with the processor, the segmented timeline including a plurality of segments, and at least one segment of the plurality of segments corresponding to the first workout activity. The method further includes generating a user interface with the processor, the user interface including the segmented timeline displayed together with at least part of the video input. The method also includes providing the user interface to a plurality of exercise machines via a network.

Abstract: A method includes receiving, with a processor in communication with a first exercise machine, a first request for an exercise class, the first request being provided by a first user of the first exercise machine. The method also includes providing a video file associated with the exercise class to the first exercise machine, providing a notification to a second user indicating that the first user has chosen to participate in the exercise class, and receiving a second request for the exercise class provided by the second user. The method further includes providing the video file to a second exercise machine of the second user via the network. In such a method, display of the video file via a display of the second exercise machine is synchronized with display of the video file via a display of the first exercise machine.

Abstract: An exercise machine includes a processor, a first display, a deck, and a belt rotatable about the deck. The machine also includes a sensor operably connected to the processor and configured to detect a first performance parameter of a first user running on the belt of the exercise machine. The processor is configured to receive information indicative of a second performance parameter of a second user, the second performance parameter being detected at an additional exercise machine during display of the at least part of the exercise class on a display associated with the additional exercise machine. The processor is also configured to cause the second performance parameter to be displayed on the first display together with the first performance parameter.

Abstract: A method includes receiving, with a processor in communication with a first exercise machine, a first request for an exercise class, the first request being provided by a first user of the first exercise machine. The method also includes providing a video file associated with the exercise class to the first exercise machine, providing a notification to a second user indicating that the first user has chosen to participate in the exercise class, and receiving a second request for the exercise class provided by the second user. The method further includes providing the video file to a second exercise machine of the second user via the network. In such a method, display of the video file via a display of the second exercise machine is synchronized with display of the video file via a display of the first exercise machine.

Abstract: The invention relates to a pharmaceutical composition containing a PLP-dependent enzyme and optionally its cofactor, pyridoxal phosphate (PLP), and/or a phosphate or non-phosphate precursor of PLP, its use as a drug, its production method and a therapeutic treatment method related to it. The pharmaceutical composition comprises erythrocytes and a pharmaceutically acceptable vehicle, the erythrocytes encapsulating the PLP-dependent enzyme. The PLP-dependent enzyme may be methioninase, tyrosine phenol-lyase, tyrosine aminotransferase or cystathionine beta-synthase.

Abstract: An exercise machine includes a processor, a first display, a deck, and a belt rotatable about the deck. The machine also includes a sensor operably connected to the processor and configured to detect a first performance parameter of a first user running on the belt of the exercise machine. The processor is configured to receive information indicative of a second performance parameter of a second user, the second performance parameter being detected at an additional exercise machine during display of the at least part of the exercise class on a display associated with the additional exercise machine. The processor is also configured to cause the second performance parameter to be displayed on the first display together with the first performance parameter.

Abstract: The invention relates to a pharmaceutical kit containing a) an injectable suspension of erythrocytes encapsulating a pyridoxal phosphate (PLP)-dependent enzyme and b) a non-phosphate PLP precursor. The invention further relates to methods of producing component(s) of the kit and to therapeutic treatment methods related to the kit. The PLP-dependent enzyme may be a methioninase, a tyrosine phenol-lyase, a tyrosine aminotransferase or a cystathionine beta-synthase.

Abstract: A method includes receiving, with a processor in communication with a first exercise machine, a first request for an exercise class, the first request being provided by a first user of the first exercise machine. The method also includes providing a video file associated with the exercise class to the first exercise machine, providing a notification to a second user indicating that the first user has chosen to participate in the exercise class, and receiving a second request for the exercise class provided by the second user. The method further includes providing the video file to a second exercise machine of the second user via the network. In such a method, display of the video file via a display of the second exercise machine is synchronized with display of the video file via a display of the first exercise machine.