Abstract: According to an example, a method of analyzing an output of a sequencer is provided comprising identifying genetic targets, obtaining target signature snippets responsive thereto, each target signature snippet derived from a genetic sequence of the genetic targets, receiving portions of a test sequence output by a sequencer sequencing a sample in real time, determining, in real time or near-real time with the sequencer sequencing the sample, whether a target signature snippet of the target signature snippets is in at least one portion of the test sequence, determining, for each genetic target, a probability the genetic target is in the sample based on the determination of whether the target signature snippet is present in the at least one portion of the test sequence, and outputting an analysis of the sample indicating the respective probability that each genetic target is present in the sample.

Abstract: According to at least one example, a method of filtering signature snippets is provided comprising identifying a group of genetic targets, obtaining a plurality of sets of one or more target signature snippets responsive to identifying the group of genetic targets, each set of one or more target signature snippets corresponding to a respective genetic target of the group of genetic targets and being derived from a genetic sequence of the respective genetic target, filtering the plurality of sets of one or more target signature snippets to identify a set of one or more universal target signature snippets, and outputting the set of one or more universal target signature snippets.