Patents by Inventor Thomas D. Eller

Thomas D. Eller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aminoalkoxy or carboxyalkoxy derivatives of propranolol for immunoassay applications
    Patent number: 4795715
    Abstract: Derivatives of propranolol which have the following structure: ##STR1## where R is X--(CH.sub.2).sub.n --O, X is NH.sub.2 or COOH, n is 1,2,3,4, or 5, provided that when n is 1, X must be COOH, and R is attached in the 4',5',6',7' or 8' position. The compounds are useful in immunoassay applications to (1) conjugate to a protein carrier in order to prepare antibodies to propranolol and (2) to conjugate to a tracer moiety such as a radiolabeled ligand, an enzyme, an enzyme substrate or a fluorescent dye.
    Type: Grant
    Filed: October 3, 1986
    Date of Patent: January 3, 1989
    Assignee: Drug Science Foundation
    Inventors: Thomas D. Eller, Daniel R. Knapp
  • Aromatic derivatives of 13-azaprostanoic acid
    Patent number: 4695647
    Abstract: Novel substituted phenyl eicosanoid analogs having the formula: ##STR1## and their pharmaceutically acceptable esters and salts, wherein: R is H or OH;R.sub.1 is H or lower alkyl;X is --CH.sub.2 --CH.sub.2 -- or cis --CH.dbd.CH--;Y is --CH.sub.2 --, ##STR2## --O-- or --S--; n is 0 or 1; and.circle.A is (1) an eicosanoid nucleus (ring system), (2) a carbocyclic analog of an eicosanoid nucleus or (3) a heterocyclic analog of an eicosanoid nucleus wherein one of the carbons in a carbocyclic analog is replaced by O, S or N.
    Type: Grant
    Filed: March 22, 1984
    Date of Patent: September 22, 1987
    Assignee: Drug Science Foundation
    Inventors: Thomas D. Eller, Perry V. Halushka, Daniel R. Knapp, Dale Mais
  • Aminoalkoxy derivatives of propranolol for immunoassay applications
    Patent number: 4652681
    Abstract: Derivatives of propranolol which have the following structure: ##STR1## where R is X--(CH.sub.2).sub.n --O, X is NH.sub.2 or COOH, n is 1,2,3,4, or 5, provided that when n is 1, X must be COOH, and R is attached in the 4', 5', 6', 7' or 8' position. The compounds are useful in immunoassay applications to (1) conjugate to a protein carrier in order to prepare antibodies to propranolol and (2) to conjugate to a tracer moiety such as a radiolabeled ligand, an enzyme, an enzyme substrate or a fluorescent dye.
    Type: Grant
    Filed: April 15, 1982
    Date of Patent: March 24, 1987
    Assignee: Drug Science Foundation
    Inventors: Thomas D. Eller, Daniel R. Knapp