Abstract: Disclosed are embodiments for the aggregation and analysis of vehicle prices via a geo-specific model. Data may be collected at various geo-specific levels such as a ZIP-Code level to provide greater data resolution. Data sets taken into account may include demarcation point data sets and data sets based on vehicle transactions. A demarcation point data set may be based on consumer market factors that influence car-buying behavior. Vehicle transactions may be classified into data sets for other vehicles having similar characteristics to the vehicle. A geo-specific statistical pricing model may then be applied to the data sets based on similar characteristics to a particular vehicle to produce a price estimation for the vehicle.

Abstract: A system, method, and computer program product for identifying consumer items more likely to be bought by an individual user. In some embodiments, a collaborative filter may be used to rank items based on the degree to which they match user preferences. The collaborative filter may be hierarchical and may take various factors into consideration. Example factors may include the similarity among items based on observable features, a summary of aggregate online search behavior across multiple users, the item features determined to be most important to the individual user, and a baseline item against which a conditional probability of another item being selected is measured.

Abstract: The present disclosure provides for compounds of formula (I) wherein A2, A3, A4, A6, A7, A8, A15, RA, R5, R9, R10A, R10B, R11, R12, R13, R14, R16, W, X, and Y have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including cancer. Also provided are pharmaceutical compositions comprising compounds of formula (I).

Abstract: An adjustable lock for a sliding member such as a sliding door, sliding panel, or sliding window is provided by a tubular mechanism adapted to be placed into a position wedging the tubular mechanism between the frame and the sliding member, with the tubular mechanism including an inner tubular member selectively threadably extendable from within an outer tubular member attached to the frame to a locked position locking the outer and inner tubular members together, with a free end of the inner tubular member is proximate an edge portion of the associated sliding member, whereby the locked together outer and inner tubes are rotatable in one direction for extending and forcing a free end of the inner tubular member into intimate contact with the edge portion of the sliding member, thereby wedging the sliding member into a locked position preventing movement thereof.

Abstract: A pet door panel or module is configured to include a pocket window opening having an open side portion to permit a ventilation screen to be slid into the pocket on centrally located tracks to provide ventilation means, and to further permit dual panel storm window means to be slid into the pocket via tracks on either side of the centrally located track to enclose the screen between the window panes to prevent air from flowing through the window opening to protect from foul weather and insulate from cold outside temperatures.

Abstract: The present pet door panel or module includes an interior pocket flap assembly cassette opening and an external frame forming a security panel track permitting a flap assembly cassette and security panel to be slidably received or removed to facilitate changing the height of the portal opening in the pet door panel or module to accommodate various size pets in the field by the consumer without the need for tools.

Abstract: An adjustable lock for a sliding member such as a sliding door, sliding panel, or sliding window is provided by a tubular mechanism adapted to be placed into a position wedging the tubular mechanism between the frame and the sliding member, with the tubular mechanism including an inner tubular member selectively threadably extendable from within an outer tubular member attached to the frame to a locked position locking the outer and inner tubular members together, with a free end of the inner tubular member is proximate an edge portion of the associated sliding member, whereby the locked together outer and inner tubes are rotatable in one direction for extending and forcing a free end of the inner tubular member into intimate contact with the edge portion of the sliding member, thereby wedging the sliding member into a locked position preventing movement thereof.

Abstract: A pet portal flap assembly has interior and exterior frames between which moveable flaps are mounted in a swinging door, or in a patio door insert, or in an exterior wall, to permit both ingress and egress of a pet. A handle operated mechanism is provided for selectively vertically positioning the moveable flaps in an uppermost position to permit both ingress and egress of a pet, in a mid-position for only permitting ingress of a pet, and in a lowermost position in which bottom portions of the flaps are locked between the interior and exterior frames to prevent any movement of the flaps.

Abstract: The present pet door panel or module comprises an interior pocket flap assembly cassette opening and an external frame forming a security panel track permitting a flap assembly cassette and security panel to be slidably received or removed to facilitate changing the height of the portal opening in the pet door panel or module to accommodate various size pets in the field by the consumer without the need for tools. This methodology can be applied to existing pet door panels currently in the market with modifications to framing members in the lowermost portion of their one piece aluminum frame construction; thereby permitting the use of a universal module or frame with changeable flap assembly cassettes for different types and sizes of pets during manufacture or in the field by consumers. In this manner consumers need not purchase a new pet door when they change a pet, they need only purchase/replace the flap assembly cassette.

Abstract: A pet door panel or module is configured to include a pocket window opening having an open side portion to permit a ventilation screen to be slid into the pocket on centrally located tracks to provide ventilation means, and to further permit dual panel storm window means to be slid into the pocket via tracks on either side of the centrally located track to enclose the screen between the window panes to prevent air from flowing through the window opening to protect from foul weather and insulate from cold outside temperatures.

Abstract: A pet portal flap assembly has interior and exterior frames between which moveable flaps are mounted in a swinging door, or in a patio door insert, or in an exterior wall, to permit both ingress and egress of a pet. A handle operated mechanism is provided for selectively vertically positioning the moveable flaps in an uppermost position to permit both ingress and egress of a pet, in a mid-position for only permitting ingress of a pet, and in a lowermost position in which bottom portions of the flaps are locked between the interior and exterior frames to prevent any movement of the flaps.

Abstract: A portable pet portal insert for a sliding patio door includes separate top, center, and bottom modules that can be assembled together through use of tongue and groove fittings therebetween, with the bottom module having a cutout portion adapted for receiving a pet portal, the pet portal including a pivotal flap, a cam operated lock for preventing movement of the flap away from an associated frame, and a weather seal mechanism.

Abstract: A DNA segment from the upstream untranscribed region of a maize ubiquitin gene is disclosed. This ubiquitin promoter region, which comprises heat shock consensus elements, initiates and regulates the transcription of genes placed under its control. Recombinant DNA molecules are also described in which a ubiquitin promoter is combined with a plant expressible structural gene for regulated expression of the structral gene and for regulated control of expression when stressed with clevated temperatures. Such recombinant DNA molecules are introduced into plant tissue so that the promoter/stuctural gene combination is expressed.

Abstract: An attention performance test uses a visual display, a test subject input device, a memory and a programmed processor coupled to each of the above to administer a test to a test subject. A test target, which for example can be a word colored in a first color but meaning another color, is attempted to be matched by the test subject to one of a series of sequentially presented visual response targets. In one embodiment, a nonvisual test stimulus is also provided to the test subject, the test subject having previously been instructed to respond to the nonvisual test stimulus (such as a beep) in a particular way. The test also measures the response latency of the test subject, i.e., whether the test subject has assumed a correct position for entering a response. The responses from the test subject are recorded and may be compared with data derived from a test subject database in assessing whether an attention deficit disorder exists.

Abstract: A method of inducibly enhancing the constitutive expression of a DNA sequence of interest is described in which plant cells are transformed with a DNA sequence of interest that is operably joined to a plant ubiquitin regulatory region comprised of a heat shock element, a promoter, a transcription start site, an intron and a translation start site, When monocot or dicot plant cells are subjected to permissive heat shock temperatures, the level of expression of the DNA sequence of interest is enhanced.

Abstract: A dark- and light-regulated chlorophyll a/b (Cab) binding protein promoter/regulatory system from maize is disclosed. This promoter/regulatory system is capable of accounting for as much as 80% of the total Cab mRNA in the dark and results in enhancement of expression from 3- to 6-fold after conditions of illumination. This Cab promoter/regulatory system may be recombined with structural genes for expression in plant cells.

Abstract: A plant chlorophyll a/b binding (Cab) protein gene was isolated from a maize genomic library. The promoter/regulatory system of this gene actively functions in controlling Cab gene expression under conditions of darkness and in enhancing gene expression under conditions of light. This invention contemplates the utilization of the Cab promoter/regulatory system in regulating non-homologous structural gene expression in transgenic plants under conditions of darkness followed by further enhancement of gene expression under conditions of light.

Abstract: A method of inducibly enhancing the constitutive expression of a DNA sequence of interest is described in which plant cells are transformed with a DNA sequence of interest that is operably joined to a plant ubiquitin regulatory region comprised of a heat shock element, a promoter, a transcription start site, an intron, and a translation start site. When monocot or dicot plant cells are subjected to permissive heat shock temperatures, the level of expression of the DNA sequence of interest is enhanced.

Abstract: A system for testing a condom includes a housing containing a porous liner having an interior cavity conformed to the exterior shape of a condom to be tested, whereby a holder carrying the condom is inserted into the liner, a closed pathway for gas flow is provided between a gas port of the holder and the interior volume of the condom, for permitting the condom to be inflated with the gas, causing the exterior walls of the condom to be pushed against opposing inside walls of the liner, permitting gas passing through holes in the condom to flow through pores in walls of the liner to another gas port of the housing for detecting unacceptable holes in the condom using differential pressure techniques and/or gas tagging.

Abstract: A DNA segment from the upstream untranscribed region of a maize ubiquitin gene is disclosed. This ubiquitin promoter region, which comprises heat shock consensus elements, initiates and regulates the transcription of genes placed under its control. Recombinant DNA molecules are also described in which a ubiquitin promoter is combined with a plant expressible structural gene for regulated expression of the structural gene and for regulated control of expression when stressed with elevated temperatures. Such recombinant DNA molecules are introduced into plant tissue so that the promoter/structural gene combination is expressed.