Patents by Inventor Thomas Dag Horn

Thomas Dag Horn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11957783
    Abstract: A method is presented for treating viral and fungal infections by applying a topical immunosensitizer to the skin of a person infected with a virus or fungus and in need of treatment for the viral or fungal infection. Methods of improving anti-viral and anti-fungal immunity are also presented, and methods of increasing PBMC interferon gamma expression in response to a viral or fungal immune stimulus.
    Type: Grant
    Filed: March 8, 2021
    Date of Patent: April 16, 2024
    Assignee: Squarex Pharmaceutical Corporation
    Inventors: Hugh McTavish, Thomas Dag Horn
  • Publication number: 20210186863
    Abstract: A method is presented for treating viral and fungal infections by applying a topical immunosensitizer to the skin of a person infected with a virus or fungus and in need of treatment for the viral or fungal infection. Methods of improving anti-viral and anti-fungal immunity are also presented, and methods of increasing PBMC interferon gamma expression in response to a viral or fungal immune stimulus.
    Type: Application
    Filed: March 8, 2021
    Publication date: June 24, 2021
    Inventors: Hugh McTavish, Thomas Dag Horn
  • Patent number: 10744084
    Abstract: A method is presented for treating herpes simplex virus (HSV) infection comprising: (a) locally administering a substance that induces a delayed type hypersensitivity (DTH) response to a patient at a site of an HSV lesion to induce a DTH response at the site of the lesion during one or more outbreaks of the HSV infection.
    Type: Grant
    Filed: November 9, 2018
    Date of Patent: August 18, 2020
    Assignees: Squarex, LLC, Bioventures, LLC
    Inventors: Hugh McTavish, Thomas Dag Horn, Sandra Marchese Johnson
  • Publication number: 20190105263
    Abstract: A method is presented for treating herpes simplex virus (HSV) infection comprising: (a) locally administering a substance that induces a delayed type hypersensitivity (DTH) response to a patient at a site of an HSV lesion to induce a DTH response at the site of the lesion during one or more outbreaks of the HSV infection.
    Type: Application
    Filed: November 9, 2018
    Publication date: April 11, 2019
    Inventors: Hugh McTavish, Thomas Dag Horn, Sandra Marchese Johnson
  • Publication number: 20160081918
    Abstract: A method is presented for treating herpes simplex virus (HSV) infection comprising: (a) locally administering a substance that induces a delayed type hypersensitivity (DTH) response to a patient at a site of an HSV lesion to induce a DTH response at the site of the lesion during one or more outbreaks of the HSV infection.
    Type: Application
    Filed: December 6, 2015
    Publication date: March 24, 2016
    Inventors: Hugh McTavish, Thomas Dag Horn, Sandra Marchese Johnson
  • Patent number: 9205065
    Abstract: A method is presented for treating herpes simplex virus (HSV) infection comprising: (a) locally administering a substance that induces a delayed type hypersensitivity (DTH) response to a patient at a site of an HSV lesion to induce a DTH response at the site of the lesion during one or more outbreaks of the HSV infection.
    Type: Grant
    Filed: April 19, 2015
    Date of Patent: December 8, 2015
    Assignee: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS
    Inventors: Hugh McTavish, Thomas Dag Horn, Sandra Marchese Johnson
  • Publication number: 20150224067
    Abstract: A method is presented for treating herpes simplex virus (HSV) infection comprising: (a) locally administering a substance that induces a delayed type hypersensitivity (DTH) response to a patient at a site of an HSV lesion to induce a DTH response at the site of the lesion during one or more outbreaks of the HSV infection.
    Type: Application
    Filed: April 19, 2015
    Publication date: August 13, 2015
    Inventors: Hugh McTavish, Thomas Dag Horn, Sandra Marchese Johnson
  • Patent number: 7846447
    Abstract: The pharmaceutical composition is useful for treating epithelial tumors in a subject and contains at least two antigens and a pharmaceutically acceptable carrier, where each of the antigens induces or is capable of inducing a cutaneous delayed type hypersensitivity (DTH) response in the subject. This composition is particularly useful in treating epithelial tumors, such as warts or verrucae, that are induced by or related to papillomavirus. Antigens useful in the present pharmaceutical composition are anergy panel antigens, such as killed mumps virus, candida extract, trichophyton extract or comparable antigenic extracts. An additional pharmaceutical composition, also useful for treating epithelial tumors, contains at least one antigen that induces or is capable of inducing a cutaneous DTH response in a subject, at least one cytokine or colony stimulating factor and a pharmaceutically acceptable carrier. Kits containing these pharmaceutical compositions are useful for this immunotherapy.
    Type: Grant
    Filed: March 19, 2008
    Date of Patent: December 7, 2010
    Assignee: The Board of Trustees of the University of Arkansas
    Inventors: Thomas Dag Horn, Sandra Marchese Johnson
  • Publication number: 20100055132
    Abstract: A method is presented for treating herpes simplex virus (HSV) infection comprising: (a) locally administering a substance that induces a delayed type hypersensitivity (DTH) response to a patient at a site of an HSV lesion to induce a DTH response at the site of the lesion during one or more outbreaks of the HSV infection.
    Type: Application
    Filed: April 4, 2008
    Publication date: March 4, 2010
    Inventors: Thomas Dag Horn, Sandra Marchese Johnson, Hugh McTavish
  • Publication number: 20080193410
    Abstract: The pharmaceutical composition is useful for treating epithelial tumors in a subject and contains at least two antigens and a pharmaceutically acceptable carrier, where each of the antigens induces or is capable of inducing a cutaneous delayed type hypersensitivity (DTH) response in the subject. This composition is particularly useful in treating epithelial tumors, such as warts or verrucae, that are induced by or related to papillomavirus. Antigens useful in the present pharmaceutical composition are anergy panel antigens, such as killed mumps virus, candida extract, trichophyton extract or comparable antigenic extracts. An additional pharmaceutical composition, also useful for treating epithelial tumors, contains at least one antigen that induces or is capable of inducing a cutaneous DTH response in a subject, at least one cytokine or colony stimulating factor and a pharmaceutically acceptable carrier. Kits containing these pharmaceutical compositions are useful for this immunotherapy.
    Type: Application
    Filed: March 19, 2008
    Publication date: August 14, 2008
    Applicant: The Board of Trustees of the University of Arkansas
    Inventors: Thomas Dag Horn, Sandra Marchese Johnson
  • Publication number: 20020142005
    Abstract: The pharmaceutical composition is useful for treating epithelial tumors in a subject and contains at least two antigens and a pharmaceutically acceptable carrier, where each of the antigens induces or is capable of inducing a cutaneous delayed type hypersensitivity (DTH) response in the subject. This composition is particularly useful in treating epithelial tumors, such as warts or verrucae, that are induced by or related to papillomavirus. Antigens useful in the present pharmaceutical composition are anergy panel antigens, such as killed mumps virus, candida extract, trichophyton extract or comparable antigenic extracts. An additional pharmaceutical composition, also useful for treating epithelial tumors, contains at least one antigen that induces or is capable of inducing a cutaneous DTH response in a subject, at least one cytokine or colony stimulating factor and a pharmaceutically acceptable carrier. Kits containing these pharmaceutical compositions are useful for this immunotherapy.
    Type: Application
    Filed: February 25, 2002
    Publication date: October 3, 2002
    Applicant: University of Arkansas
    Inventors: Thomas Dag Horn, Sandra Marchese Johnson
  • Patent number: 6350451
    Abstract: The present immunotherapy relates to a method of treating epithelial tumors and the pharmaceutical compositions and kits useful in treating such tumors. The immunotherapy comprises injecting an effective amount of a pharmaceutical composition containing at least one antigen into the tumor, wherein the antigen is selected for inducing or having the ability to induce a cutaneous delayed type hypersensitivity (DTH) response in the subject prior to the injection of the antigen into the tumors. This immunotherapy is particularly useful in treating epithelial tumors, such as warts or verrucae, that are induced by or related to papillomavirus. Antigens useful in the present immunotherapy are anergy panel antigens, such as killed mumps virus, candida extract, trichophyton extract or comparable antigenic extracts.
    Type: Grant
    Filed: June 25, 1999
    Date of Patent: February 26, 2002
    Assignee: The Board of Trustees of the University of Arkansas
    Inventors: Thomas Dag Horn, Sandra Marchese Johnson