Patents by Inventor Thomas Darling

Thomas Darling has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modulation of blood brain barrier protein expression
    Patent number: 8466118
    Abstract: There are disclosed agents that inhibit Blood Brain Barrier Proteins (BBBP). Such agents are useful in controlling agents entering and exiting the CNS. This allows for drugs to be more effective and/or allowing side effects of the drugs to be lowered.
    Type: Grant
    Filed: April 23, 2008
    Date of Patent: June 18, 2013
    Assignee: Saint Louis University
    Inventors: William A. Banks, Vijaya B. Kumar, Thomas Darling, Robert Clayton
  • Antisense Modulation Of Amyloid Beta Protein Expression
    Publication number: 20110166197
    Abstract: Antisense nucleic acids, compositions and methods are provided for modulating the expression of an amyloid beta protein (A?P) portion of the amyloid precursor protein (APP) coding sequence. The compositions comprise antisense nucleic acids targeted to nucleic acids encoding amyloid precursor protein. Methods of using these nucleic acids for modulation of amyloid precursor protein expression and for treatment of diseases and conditions associated with expression of the amyloid beta protein portion of the amyloid precursor protein are provided.
    Type: Application
    Filed: February 19, 2009
    Publication date: July 7, 2011
    Applicant: EDUNN BIOTECHNOLOGY, INC.
    Inventors: Thomas Darling, Vijaya B. Kumar, William A. Banks, Susan Farr, John E. Morley
  • MODULATION OF BLOOD BRAIN BARRIER PROTEIN EXPRESSION
    Publication number: 20100196393
    Abstract: There are disclosed agents that inhibit Blood Brain Barrier Proteins (BBBP). Such agents are useful in controlling agents entering and exiting the CNS. This allows for drugs to be more effective and/or allowing side effects of the drugs to be lowered.
    Type: Application
    Filed: April 23, 2008
    Publication date: August 5, 2010
    Applicant: ST. LOUIS UNIVERSITY
    Inventors: William A. Banks, Vijaya B. Kumar, Thomas Darling, Robert Clayton
  • Decolorization of oligomers
    Publication number: 20070191523
    Abstract: Methods of producing decolorized homo- and co-polymers through polymerization of monomers in presence of cobalt-complexed tetraphenyl porphyrin derivatives and decolorization of the produced polymer by exposing the polymer to a sorbent and, optionally, a solvent are disclosed herein.
    Type: Application
    Filed: November 9, 2006
    Publication date: August 16, 2007
    Inventors: Bradford Wayland, Zhi Lu, Alexei Gridnev, Thomas Darling
  • Branched polymers and coating compositions made therefrom
    Publication number: 20050054767
    Abstract: This invention relates to rapid curing coating compositions that are particularly useful for automotive OEM and refinish applications. The coating composition includes a crosslinkable component that contains a novel highly branched acrylic polymer, and a crosslinking component that contains conventional crosslinking agents, such as polyisocyanate and melamine. This invention is also directed to a process for producing coatings from the rapid curing coating compositions. These compositions are especially useful in providing hard highly crosslinked coatings.
    Type: Application
    Filed: July 7, 2004
    Publication date: March 10, 2005
    Inventors: Thomas Darling, Robert Barsotti, Alexei Gridnev, Patricia Sormani