Patents by Inventor Thomas David

Thomas David has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12371718
    Abstract: Disclosed herein are methods and compositions for catalytic glycolysis to deconstruct PET to bis(2-hydroxyethyl) terephthalate (BHET). For BHET conversion to terephthalate and ethylene glycol, we engineer Pseudomonas putida KT2440 with PETase and MHETase enzymes from Ideonella sakaiensis. We further engineer P. putida to convert terephthalate to a performance-advantaged bioproduct, ?-ketoadipic acid, and for improved utilization of ethylene glycol, a byproduct of BHET catabolism. In a bioreactor, we produce 15.1±0.6 g/L of ?-ketoadipic acid (?KA) from BHET at 76±3% molar yield. Lastly, we demonstrate conversion of catalytically depolymerized PET to ?KA. Overall, this work highlights the potential of tandem catalytic deconstruction and biological conversion as a means to upcycle waste PET.
    Type: Grant
    Filed: March 10, 2021
    Date of Patent: July 29, 2025
    Assignees: Alliance for Sustainable Energy, LLC, UT-Battelle, LLC
    Inventors: Gregg Tyler Beckham, Thelhawadigedara Lahiru Niroshan Jayakody, Adam Michael Guss, Thomas David Mand, Christopher W. Johnson, Isabel Pardo Mendoza, Allison Jean Zimont Werner
  • Publication number: 20250228811
    Abstract: The application provides a novel triester compound and the pharmaceutical composition and formulation thereof, as well as a method of using the triester compound for the treatment of, inter alia, an inflammatory-related disease or disorder.
    Type: Application
    Filed: December 18, 2024
    Publication date: July 17, 2025
    Inventors: Stuart Paul ROMERIL, Jing LI, Keith BENTLEY, Thomas David DOWNES, Lawrence K. CHAN, Michael Joseph ARDOLINO, Christoph BOSS, Gregor MEIER, Pierre THESMAR, Roberta PROPERZI, Fabian GLATZ, Denis BUCHER, Christopher HOSFORD
  • Publication number: 20250206115
    Abstract: A seal assembly is adapted to be coupled to a flange of a vehicle. The seal assembly includes a seal body extruded from an elastomeric material and having a base, a first leg, and a second leg collectively defining a mounting channel for receiving the flange of the vehicle. The seal assembly also includes at least one seal feature co-extruded with the seal body, extending from the body, and spaced from the mounting channel. The seal assembly further includes a molded component coupled to the seal body and molded from a thermoplastic material. The seal assembly further includes an electromagnetic adhesive disposed between the seal body and the molded component. The electromagnetic adhesive includes a resin and a susceptor configured to be energized upon exposure to electromagnetic energy such that the susceptor softens the resin to directly mount the molded component to the seal body.
    Type: Application
    Filed: May 19, 2023
    Publication date: June 26, 2025
    Applicant: Henniges Automotive Sealing Systems North America, Inc.
    Inventors: Thomas David Groters, Arthur Allen Krajenke, Henry G. Zilka
  • Publication number: 20250194640
    Abstract: The present disclosure provides methods for reducing methane emissions from a ruminant comprising administering to the ruminant bromoform produced by a composition comprising: bromide, and a vanadium-dependent haloperoxidase (VHPO) comprising SEQ ID NO: 2 or a variant protein thereof.
    Type: Application
    Filed: March 6, 2025
    Publication date: June 19, 2025
    Inventors: Abed CHAUDHURY, Karen PACO, Michael Anthony AYLIFFE, Thomas David LOAN, Ming LUO, Tristan YANG
  • Patent number: 12330999
    Abstract: Provided in the invention are thiosulfate-urea based products (IIa) and/or a polysulfide-urea based products (IIb) and/or a (bi)sulfite-urea based products (IIc) suitable for use in fertilizers and comprising: one or more urea-containing compounds (a), one or more compounds (b), optionally, one or more urease (c1) and/or nitrification (c2) inhibitors that are different from compounds (b), and/or optionally, one or more additives (d) that are different from any of the above compounds, wherein the amount of water (e) in the product (II) is less than about 10 wt %, preferably less than about 5 wt %, wherein compounds (a) are selected from urea (a1) and/or from urea-aldehyde products (a2) and/or from urea-triazone compounds (a3), wherein compounds (b) are selected from thiosulfates (b1) and/or from polysulfides (b2) and/or from (bi)sulfites (b3). An advantage of products of the invention is that only minimal amounts of degradation products of compounds (b) are formed.
    Type: Grant
    Filed: August 7, 2019
    Date of Patent: June 17, 2025
    Assignee: Tessenderlo Group NV
    Inventors: Michael Massoud Hojjatie, Thomas David Fairweather, Jeroen Van Cauwenbergh, Martijn Timmermans, Heidi van den Rul
  • Patent number: 12331002
    Abstract: Provided in the invention is a stabilized fertilizer composition (I) suitable for use in fertilizers and comprising: Urea (a), One or more compounds (b), One or more urease inhibitors (c1) and/or one or more nitrification inhibitors (c2), optionally provided in one or more carriers (d), said compounds (c) being different from compounds (b), Optionally one or more additives (e) different from any of the above, and Water (f) in an amount less than about 10 wt % and preferably less than about 5 wt %; wherein compounds (b) are selected from thiosulfates (b1) and/or from polysulfides (b2) and/or from (bi)sulfites (b3); and wherein the ratio of urea (a) to compounds (b) is from 1:99 to 99:1, preferably from 2:98 to 98:2. Products of the invention can be made in various forms and in different ways. All of the materials of the invention are suitable for use in fertilizers and blend well with solid and liquid fertilizers standardly used. They have excellent shelf life and provide good urea-N protection.
    Type: Grant
    Filed: August 7, 2019
    Date of Patent: June 17, 2025
    Assignee: Tessenderlo Group NV
    Inventors: Michael Massoud Hojjatie, Thomas David Fairweather, Jeroen Van Cauwenbergh, Martijn Timmermans, Heidi van den Rul
  • Publication number: 20250171400
    Abstract: The invention provides aza-heterocyclyl carboxamide and related compounds, pharmaceutical compositions, and their use in the treatment of medical conditions, such as bacterial infections, and in inhibiting LpxC activity.
    Type: Application
    Filed: January 24, 2025
    Publication date: May 29, 2025
    Inventors: Michael Dominic Ryan, Thomas David Pallin, Toby Jonathan Blench, Toby Matthew Grover Mullins, David Edward Clark, Emanuela Gancia, Nadia Mamoona Ahmad
  • Publication number: 20250161601
    Abstract: An article for use with an apparatus for heating aerosol generating agent to volatilize at least one component of the aerosol generating agent, the article including a support layer having a first surface, wherein at least a portion of the first surface is rough and an aerosol generating agent on the portion of the first surface that is rough.
    Type: Application
    Filed: January 17, 2025
    Publication date: May 22, 2025
    Inventors: Kaveh GHANOUNI, Richard HEPWORTH, Walid ABI AOUN, Karl KALJURA, Thomas David LEAH, Shasa HARRIS
  • Publication number: 20250147714
    Abstract: Various implementations include devices and approaches for controlling an audio system. In particular cases, a device with a rotatable feature having distinct operating modes is used to control a remote audio device. The rotatable feature can enable multi-aspect control of audio output at an audio device.
    Type: Application
    Filed: November 6, 2023
    Publication date: May 8, 2025
    Inventors: Lauren Taylor Westendorf, Joel Henry Miller, Jenna Marie Duggan-Lykes, Todd Richard Reily, Thomas David Chambers, Zachary James McHugh
  • Patent number: 12286411
    Abstract: The invention relates to an indane compound according to Formula (I), or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, R6, L, n and p are as defined herein. The compounds are useful for treating antibacterial infection either as stand-alone antibiotics, or in combination with further antibiotics.
    Type: Grant
    Filed: July 25, 2019
    Date of Patent: April 29, 2025
    Assignee: Antabio SAS
    Inventors: Simon Leiris, David Thomas Davies, Martin Everett, Nicolas Sprynski, Lilha Beyria, Thomas David Pallin, Andrew Peter Cridland, Toby Jonathan Blench, Richard Leonard Elliott, David Edward Clark
  • Patent number: 12265045
    Abstract: Apparatus and method for determining a characteristic of a material within a region. One apparatus includes a first plurality of electrodes, a stimulation monitor monitoring an electrical parameter at a plurality of other electrodes of said first plurality of electrodes in response to an applied stimulation signal, a monitor, and a controller. The stimulation monitor generating a received stimulation signal for each of said plurality of other electrodes. The monitor generating a series of data values, each data value being indicative of a phase difference and/or an amplitude relationship between the applied stimulation signal and the received stimulation signal associated with one of the plurality of other electrodes, said series of data values defining an electromagnetic fingerprint.
    Type: Grant
    Filed: March 30, 2021
    Date of Patent: April 1, 2025
    Assignee: INDUSTRIAL TOMOGRAPHY SYSTEMS LTD.
    Inventors: Thomas David Machin, Hsin-Yu Wei
  • Patent number: 12256759
    Abstract: The present disclosure provides methods for reducing methane emissions from a ruminant comprising administering to the ruminant a composition comprising a fungal strain, wherein the fungal strain comprises a vanadium-dependent haloperoxidase (VHPO) such as Curvularia sp. strain 4388 (NMI Accession No. V22/011149). The disclosure also provides a cell or a biologically pure culture of Curvularia sp. strain 4388 (NMI Accession No. V22/011149) or a mutant thereof having all identifying characteristics of the strain.
    Type: Grant
    Filed: August 2, 2022
    Date of Patent: March 25, 2025
    Assignee: Loam Bio Pty Ltd
    Inventors: Abed Chaudhury, Karen Paco, Michael Anthony Ayliffe, Thomas David Loan, Ming Luo, Tristan Yang
  • Patent number: 12257383
    Abstract: An article for use with an apparatus for heating aerosol generating agent to volatilize at least one component of the aerosol generating agent, the article including a support layer having a first surface, wherein at least a portion of the first surface is rough and an aerosol generating agent on the portion of the first surface that is rough.
    Type: Grant
    Filed: January 4, 2023
    Date of Patent: March 25, 2025
    Assignee: NICOVENTURES TRADING LIMITED
    Inventors: Kaveh Ghanouni, Richard Hepworth, Walid Abi Aoun, Karl Kaljura, Thomas David Leah, Shasa Harris
  • Patent number: 12247013
    Abstract: The invention relates to an indane compound according to Formula (I), or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, R6, L, n and p are as defined herein. The compounds are useful for treating antibacterial infection either as stand-alone antibiotics, or in combination with further antibiotics.
    Type: Grant
    Filed: July 25, 2019
    Date of Patent: March 11, 2025
    Assignee: Antabio SAS
    Inventors: Simon Leiris, David Thomas Davies, Martin Everett, Nicolas Sprynski, Lilha Beyria, Thomas David Pallin, Andrew Peter Cridland, Toby Jonathan Blench, Richard Leonard Elliott, David Edward Clark
  • Patent number: 12227475
    Abstract: The invention provides aza-heterocyclyl carboxamide and related compounds, pharmaceutical compositions, and their use in the treatment of medical conditions, such as bacterial infections, and in inhibiting LpxC activity.
    Type: Grant
    Filed: April 27, 2022
    Date of Patent: February 18, 2025
    Inventors: Michael Dominic Ryan, Thomas David Pallin, Toby Jonathan Blench, Toby Matthew Grover Mullins, David Edward Clark, Emanuela Gancia, Nadia Mamoona Ahmad
  • Patent number: 12225926
    Abstract: An aerosol generating substrate comprising an aerosol generating material, wherein the aerosol generating material comprises an amorphous solid, the amorphous solid comprising 1-60 wt % of a gelling agent; 5-80 wt % of an aerosol generating agent; and 1-70 wt % of an active ingredient; wherein these weights are calculated on a dry weight basis; wherein bi-modal or multi-modal release of one or more active ingredients of the amorphous solid is observed in use.
    Type: Grant
    Filed: July 31, 2019
    Date of Patent: February 18, 2025
    Assignee: NICOVENTURES TRADING LIMITED
    Inventors: Kav Ghanouni, Thomas David Leah, Jocelyn Benning
  • Publication number: 20250051805
    Abstract: The present invention relates to methods of increasing bromoform production.
    Type: Application
    Filed: June 24, 2022
    Publication date: February 13, 2025
    Applicant: Commonwealth Scientific and Industrial Research Organisation
    Inventors: Michael Anthony AYLIFFE, Thomas David Loan, Ming Luo
  • Publication number: 20250037850
    Abstract: A computer system and method for generating non-fungible tokens (NFTs) representing a company asset based on evaluation of company assets (e.g., a hospital). Stored in a database are one or more digital assets (e.g., one or more of settlement rights and insurance claim payment obligations) representative of contractual obligations owed to the company (e.g., settlement rights), which are then analyze to determine one or more assets owed to the company. A valuation value is then determined for the determined one or more assets. NFTs are then generated based on the determined valuation value of the determined one or more assets. Additionally, the generated NFTs may be leveraged as collateral in an underwriting process. Further, analyzed in real-time, is a revenue cycle management of the company for generating a risk-weighted index value indicative of the revenue cycle management.
    Type: Application
    Filed: October 16, 2024
    Publication date: January 30, 2025
    Applicant: JTS Ventures, Inc.
    Inventors: Thomas David Stewart, JR., Julie Antoniette Echols Stewart, Chris Merle Langley, Randal Lawrence Wynn
  • Publication number: 20250036504
    Abstract: Methods of performing updates to a software image that is disposed in a read only memory or a one time programmable memory device are disclosed. The method includes causing an ECC error at the beginning of a function that has been modified. This ECC error causes an exception. The exception handler determines the address where the ECC error was detected was located and searches a dictionary. This dictionary contains entries that each have an original address in the ROM or OTP Memory and the patch address in a nonvolatile writable memory. The exception handler then causes the processing unit to jump to the patch address, where a modified function is located.
    Type: Application
    Filed: July 24, 2023
    Publication date: January 30, 2025
    Inventor: Thomas David
  • Patent number: D1059277
    Type: Grant
    Filed: March 21, 2022
    Date of Patent: January 28, 2025
    Assignee: Bose Corporation
    Inventors: Ethan J. Colburn, George E. P. Chute, Richard Lionel Lanoue, Thomas David Chambers, Paul C. Williamson