Patents by Inventor Thomas DeKoning

Thomas DeKoning has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMBINATION OF GYRASE B INHIBITORS AND PROTEIN SYNTHESIS INHIBITORS AND USES THEREOF
    Publication number: 20070281992
    Abstract: The present invention relates to compounds and methods of treating, preventing, or lessening the severity of drug-resistant Gram-positive bacterial infections in mammals. The compounds consist of a combination of a gyrase B inhibitor and a protein synthesis inhibitor. These compounds demonstrate antibacterial activity against drug-resistant strains of Gram-positive bacteria, and in particular, methicillin-resistant Staphylococcus aureus (MRSA). Methods for inhibiting the activity of strains of Gram-positive bacteria and methods for treating a bacterial infection caused by such organisms are described herein.
    Type: Application
    Filed: April 2, 2007
    Publication date: December 6, 2007
    Inventors: Donald Batts, Thomas DeKoning