Patents by Inventor Thomas Dix

Thomas Dix has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Non-natural amino acids
    Patent number: 9359291
    Abstract: This invention relates in one aspect to non-natural desamino alkyl amino acid compounds, methods of making these compounds, and peptides containing these compounds. In one embodiment, the peptide is neurotensin (8-13) in which the N-terminus is an alpha-desamino, alpha-methyl-N,N-dimethyl-homolysine residue of the invention.
    Type: Grant
    Filed: March 4, 2013
    Date of Patent: June 7, 2016
    Assignee: MUSC Foundation for Research Development
    Inventor: Thomas A. Dix
  • Non-Natural Amino Acids and Neurotensin Analogues Thereof
    Publication number: 20100130432
    Abstract: This invention relates to non-natural desamino amino acid compounds, methods of making, and peptides containing these compounds as their N-terminus moieties. A preferred example is neurotensin (8-13) in which the N terminus is an alpha desamino N,N dimethyl homolysine residue.
    Type: Application
    Filed: December 15, 2006
    Publication date: May 27, 2010
    Inventors: Justin O. Brower, Thomas A. Dix
  • Non-natural amino acids and neurotensin analogues
    Publication number: 20080234202
    Abstract: This invention relates to methods of synthesis of amino acid analogs contained within peptide sequences that is adapted for preparation of peptides containing analogs of basic amino acids lysine and arginine.
    Type: Application
    Filed: April 17, 2007
    Publication date: September 25, 2008
    Inventors: Justin O. Brower, Thomas A. Dix
  • Non-Natural Amino Acids
    Publication number: 20080139481
    Abstract: This invention relates to non-natural desamino alkyl amino acid compounds, methods of making, and peptides containing these compounds as their N-terminus moieties. A preferred example is neurotensin (8-13) in which the N terminus is an alpha desamino, alpha methyl N,N dimethyl homolysine residue.
    Type: Application
    Filed: June 17, 2005
    Publication date: June 12, 2008
    Inventor: Thomas A. Dix
  • HIGH FREQUENCY CONNECTOR ASSEMBLY
    Publication number: 20070184681
    Abstract: A connector or connector assembly having a signal array having at least one shielded conductor having opposite ends and including an axial conductive element and an outer conductive element surrounding the axial conductive element and a compressible interface element positioned at least one of the opposite ends of the signal array, the interface element including a layer of insulating material having a plurality of conductive elements extending through the insulating material layer. When compressed between the signal array and a signal-bearing component, the compressible interface element maintains the geometric arrangement of the axial conductive element and the outer conductive element to the signal-bearing component. A connector assembly may include a circuit board including land areas arranged in a shielded configuration, and corresponding to the shielded land areas on the component and a second compressible interface element.
    Type: Application
    Filed: January 31, 2007
    Publication date: August 9, 2007
    Inventors: Christopher Tutt, Kenneth Peters, Thomas Dix
  • High frequency connector assembly
    Publication number: 20050233610
    Abstract: A connector or connector assembly having a signal array having at least one shielded conductor having opposite ends and including an axial conductive element and an outer conductive element surrounding the axial conductive element and a compressible interface element positioned at least one of the opposite ends of the signal array, the interface element including a layer of insulating material having a plurality of conductive elements extending through the insulating material layer. When compressed between the signal array and a signal-bearing component, the compressible interface element maintains the geometric arrangement of the axial conductive element and the outer conductive element to the signal-bearing component. A connector assembly may include a circuit board including land areas arranged in a shielded configuration, and corresponding to the shielded land areas on the component and a second compressible interface element.
    Type: Application
    Filed: May 20, 2005
    Publication date: October 20, 2005
    Inventors: Christopher Tutt, Kenneth Peters, Thomas Dix
  • Positively charged non-natural amino acids, methods of making and using thereof in peptides
    Patent number: 6858396
    Abstract: This invention relates to positively charged non-natural amino acids, methods of making thereof, and utilization thereof in peptides.
    Type: Grant
    Filed: March 6, 2002
    Date of Patent: February 22, 2005
    Assignee: Medical University of South Carolina
    Inventor: Thomas A. Dix
  • Positively charged non-natural amino acids, methods of making thereof, and use thereof in peptides
    Patent number: 6783946
    Abstract: This invention relates to positively charged non-natural amino acids, methods of making thereof, and utilization thereof in peptides. In one embodiment, the invention relates to non-natural amino acids that closely replicate the natural amino acids lysine and arginine.
    Type: Grant
    Filed: January 10, 2002
    Date of Patent: August 31, 2004
    Assignee: Medical University of South Carolina
    Inventor: Thomas A. Dix
  • Positively charged non-natural amino acids, methods of making and using thereof in peptides
    Patent number: 6566330
    Abstract: This invention relates to positively charged non-natural amino acids, methods of making thereof, and utilization thereof in peptides.
    Type: Grant
    Filed: September 11, 2000
    Date of Patent: May 20, 2003
    Assignee: Medical University of South Carolina Foundation Research Development
    Inventor: Thomas A. Dix
  • Positively charged non-natural amino acids, methods of making and using thereof in peptides
    Publication number: 20020137730
    Abstract: This invention relates to positively charged non-natural amino acids, methods of making thereof, and utilization thereof in peptides.
    Type: Application
    Filed: March 6, 2002
    Publication date: September 26, 2002
    Applicant: Medical University of South Carolina
    Inventor: Thomas A. Dix
  • Positively charged non-natural amino acids, methods of making thereof, and use thereof in peptides
    Publication number: 20020068701
    Abstract: This invention relates to positively charged non-natural amino acids, methods of making thereof, and utilization thereof in peptides. In one embodiment, the invention relates to non-natural amino acids that closely replicate the natural amino acids lysine and arginine.
    Type: Application
    Filed: January 10, 2002
    Publication date: June 6, 2002
    Applicant: Medical University of South Carolina
    Inventor: Thomas A. Dix
  • Positively charged non-natural amino acids, methods of making thereof, and use thereof in peptides
    Patent number: 6358922
    Abstract: This invention relates to positively charged non-natural amino acids, methods of making thereof, and utilization thereof in peptides. In one embodiment, the invention relates to non-natural amino acids that closely replicate the natural amino acids lysine and arginine.
    Type: Grant
    Filed: December 1, 1999
    Date of Patent: March 19, 2002
    Assignee: Medical University of South Carolina
    Inventor: Thomas A. Dix
  • Positively charged non-natural amino acids, methods of making thereof, and use thereof in peptides
    Patent number: 6043218
    Abstract: This invention relates to positively charged non-natural amino acids, methods of making thereof, and utilization thereof in peptides. In one embodiment, the invention relates to non-natural amino acids that closely replicate the natural amino acids lysine and arginine.
    Type: Grant
    Filed: October 22, 1996
    Date of Patent: March 28, 2000
    Assignee: Medical University of South Carolina
    Inventor: Thomas A. Dix