Patents by Inventor Thomas Durand-Reville

Thomas Durand-Reville has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Beta-lactamase inhibitor compounds
    Patent number: 9309245
    Abstract: The present invention is directed to compounds which are beta-lacatamase inhibitors. The compounds and their pharmaceutically acceptable salts, are useful in combination with beta-lactam antibiotics, or alone, for the treatment of bacterial infections, including infections caused by drug resistant organisms, including multi-drug resistant organisms. The present invention includes compounds according to formula (Ia): or a pharmaceutically acceptable salt thereof, wherein the values of R1, R2, R3 and R4 are described herein.
    Type: Grant
    Filed: April 2, 2013
    Date of Patent: April 12, 2016
    Assignee: Entasis Therapeutics Limited
    Inventors: Helen McGuire, Shanta Bist, Neil Bifulco, Liang Zhao, Ye Wu, Hoan Huynh, Hui Xiong, Janelle Comita-Prevoir, Daemian Dussault, Bolin Geng, Brendan Chen, Thomas Durand-Reville, Satenig Guler
  • Beta-Lactamase Inhibitor Compounds
    Publication number: 20150073011
    Abstract: The present invention is directed to compounds which are beta-lacatamase inhibitors. The compounds and their pharmaceutically acceptable salts, are useful in combination with beta-lactam antibiotics, or alone, for the treatment of bacterial infections, including infections caused by drug resistant organisms, including multi-drug resistant organisms. The present invention includes compounds according to formula (Ia): or a pharmaceutically acceptable salt thereof, wherein the values of R1, R2, R3 and R4 are described herein.
    Type: Application
    Filed: April 2, 2013
    Publication date: March 12, 2015
    Applicant: ASTRAZENECA AB
    Inventors: Helen McGuire, Shanta Bist, Neil Bifulco, Liang Zhao, Ye Wu, Hoan Huynh, Hui Xiong, Janelle Comita-Prevoir, Daemian Dussault, Bolin Geng, Brendan Chen, Thomas Durand-Reville, Satenig Guler
  • MODULATORS OF INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE
    Publication number: 20110021513
    Abstract: The present invention relates to modulators of IRAK kinase and provides compositions comprising such modulators, as well as methods therewith for treating conditions or diseases mediated by or associated with IRAK kinase.
    Type: Application
    Filed: September 7, 2007
    Publication date: January 27, 2011
    Applicant: Biogen Idec Ma Inc.
    Inventors: Thomas Durand-Reville, Charles Jewell, Charles Hammond, Donovan Chin
  • Arylphenylamino-,Arylphenylamide-, and Arylphenylether-Sulfide Derivatives
    Publication number: 20070259863
    Abstract: The present invention relates in part to compounds of formulas I and III: and pharmaceutically-acceptable salts and prodrugs thereof. These compounds can be useful for treating diseases such as inflammatory and immune diseases. The present invention also relates to pharmaceutical compositions comprising these compounds, and to methods of inhibiting inflammation or suppressing immune response in a subject.
    Type: Application
    Filed: April 28, 2005
    Publication date: November 8, 2007
    Applicants: ICOS Corporation, Biogen Idec MA Inc.
    Inventors: Donovan Chin, Thomas Durand-Reville, Francine Farouz, Kerry Fowler, Kevin Guckian, Irina Jaconbson, Ramesh Kasar, Russell Petter, Daniel Scott, C. Gregory Sowell, Eugene Thorsett, Edward Yin-Shiang Lin