Abstract: An orthopaedic knee prosthesis includes a tibial insert and a femoral component configured to articulate on the tibial insert. The tibial insert includes a lateral articular surface and medial articular surface that is asymmetrically shaped relative to the lateral articular surface. The medial articular surface is shaped to reduce anterior translation of a medial condyle of the femoral component, while the lateral articular surface is shaped to allow a lateral condyle of the femoral component to pivot, relative to the medial articular surface, along an arcuate articular path. Additionally, one or both condyles of the femoral component may include a femoral articular surface having a curved femoral surface section defined by a continuously decreasing radius of curvature.

Abstract: A defined peak region residing between about 3.2 and 3.4 ppm of a proton NMR spectrum of an in vitro biosample is electronically evaluated to determine a level of trimethylamine-N-oxide (“TMAO”). The biosample may be any suitable biosamples including human serum with a normal biologic range of between about 1-50 ?M or urine with a normal biologic range of between about 0-1000 ?M.

Abstract: Methods, systems and circuits evaluate a subject's risk of developing type 2 diabetes or developing or having prediabetes using at least one defined mathematical model of risk of progression that can stratify risk for patients having the same glucose measurement. The model may include NMR derived measurements of GlycA and a plurality of selected lipoprotein components of at least one biosample of the subject.

Abstract: Disclosed is a closed-cell polyisocyanurate foam composition capable of high compressive strength at temperatures up to 200° C. The new composition further exhibits no loss or degradation in conventional mechanical properties—less than that which impacts the intended use. The formulation of the present invention is based on the reaction product of a isocyanate and an epoxide resin catalyzed by a mixture of a tertiary amine and a cyclic amine. Compressive strength is augmented by incorporating a large fraction of a non-reactive bulk filler into the precursor polymer gel.

Abstract: A ribbon-like sensor assembly is described wherein a length of an optical fiber embedded within a similar lengths of a prepreg tow. The fiber is “sandwiched” by two layers of the prepreg tow which are merged to form a single consolidated ribbon. The consolidated ribbon achieving a generally uniform distribution of composite filaments near the embedded fiber such that excess resin does not “pool” around the periphery of the embedded fiber.

Abstract: A trailer platform for positioning on a trailer for standing on while loading and unloading a boat. The trailer platform includes a pair of elongate members having a first end, a second end, and an inner surface. A first coupling member is coupled to a first end of a first of the elongate members and removably secured to a yolk of a trailer. A second coupling member is coupled to a first end of a second of the elongate members and removably secured to the yolk. A third coupling member is coupled to the second end of the first elongate member and the second end of the second elongate member. The third coupling member is removably coupled to a hitch bar. Each one of a pair of mesh portions is securely attached to and extends away from one of the inner surfaces of the elongate members.

Abstract: An apparatus and method is described wherein a sensor, such as a mechanical strain sensor, embedded in a fiber core, is “flagged” to identify a preferred orientation of the sensor. The identifying “flag” is a composite material, comprising a plurality of non-woven filaments distributed in a resin matrix, forming a small planar tab. The fiber is first subjected to a stimulus to identify the orientation providing the desired signal response, and then sandwiched between first and second layers of the composite material. The fiber, and therefore, the sensor orientation is thereby captured and fixed in place.

Abstract: A device is described wherein a length of a optical fiber embedded within a composite matrix, in particular within a similar length of a prepreg tow. The fiber is “sandwiched” by two layers of the tow which are merged to form a single consolidated block. The consolidated block achieving a generally uniform distribution of composite filaments near the embedded fiber such that excess resin is prevented from “pooling” around the periphery of the fiber.

Abstract: Adsorbent media are prepared by contacting support material with iron containing solutions, followed by drying to coat the support material with iron. Support materials such as sand and olivine are described. The adsorbent material can be used to remove metal contaminants and natural organic matter from water.