Patents by Inventor Thomas E. Bulera

Thomas E. Bulera has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for reducing adventitious agents and toxins and cell culture reagents produced thereby
    Publication number: 20040022666
    Abstract: The present invention relates generally to a method to reduce, substantially reduce, inactivate or eliminate adventitious agents and/or toxins in a sample, particuarly in nutritive media, media supplements, media subgroups and buffer formulations. Specifically, the present invention provides powdered nutritive media, media supplements and media subgroups produced by the methods of the invention, particuarly cell culture media supplements (including powdered sera such as powdered fetal bovine serum (FBS)). The invention further provides powdered buffer formulations produced by the methods of the invention. The invention also provides kits and methods for cultivation of prokaryotic and eukaryotic cells, particularly bacterial cells, yeast cells, plant cells and animal cells (including human cells) using these nutritive media, media supplements, media subgroups and buffer formulations.
    Type: Application
    Filed: July 11, 2003
    Publication date: February 5, 2004
    Applicant: Invitrogen Corporation
    Inventors: William C. Biddle, Richard M. Fike, Barbara M. Dadey, Thomas E. Bulera
  • Methods for reducing adventitious agents and toxins and cell culture reagents produced thereby
    Patent number: 6627426
    Abstract: The present invention relates generally to a method to reduce, substantially reduce, inactivate or eliminate adventitious agents and/or toxins in a sample, particuarly in nutritive media, media supplements, media subgroups and buffer formulations. Specifically, the present invention provides powdered nutritive media, media supplements and media subgroups produced by the methods of the invention, particuarly cell culture media supplements (including powdered sera such as powdered fetal bovine serum (FBS)). The invention further provides powdered buffer formulations produced by the methods of the invention. The invention also provides kits and methods for cultivation of prokaryotic and eukaryotic cells, particularly bacterial cells, yeast cells, plant cells and animal cells (including human cells) using these nutritive media, media supplements, media subgroups and buffer formulations.
    Type: Grant
    Filed: May 23, 2000
    Date of Patent: September 30, 2003
    Assignee: Invitrogen Corporation
    Inventors: William C. Biddle, Richard M. Fike, Barbara M. Dadey, Thomas E. Bulera
  • Methods for reducing adventitious agents and toxins and cell culture reagents produced thereby
    Publication number: 20020015999
    Abstract: The present invention relates generally to a method to reduce, substantially reduce, inactivate or eliminate adventitious agents and/or toxins in a sample, particuarly in nutritive media, media supplements, media subgroups and buffer formulations. Specifically, the present invention provides powdered nutritive media, media supplements and media subgroups produced by the methods of the invention, particuarly cell culture media supplements (including powdered sera such as powdered fetal bovine serum (FBS)). The invention further provides powdered buffer formulations produced by the methods of the invention. The invention also provides kits and methods for cultivation of prokaryotic and eukaryotic cells, particularly bacterial cells, yeast cells, plant cells and animal cells (including human cells) using these nutritive media, media supplements, media subgroups and buffer formulations.
    Type: Application
    Filed: May 23, 2000
    Publication date: February 7, 2002
    Inventors: William C. Biddle, Richard M. Fike, Barbara M. Dadey, Thomas E. Bulera