Patents by Inventor Thomas E. Carey

Thomas E. Carey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for diagnosing, predicting therapeutic response of, and monitoring autoimmune disease
    Patent number: 7829292
    Abstract: The present invention provides methods of diagnosing the presence of an autoimmune disease in a patient, methods of predicting the response of an autoimmune diseased patient to therapeutic treatment, and methods of monitoring an autoimmune patient's response to therapy. In particular, these methods comprise the use of a glycoprotein from the inner-ear organ of Corti reactive with a KHRI-3 monoclonal antibody.
    Type: Grant
    Filed: April 18, 2006
    Date of Patent: November 9, 2010
    Assignee: The Regents of the University of Michigan
    Inventors: Thomas E. Carey, Thankam S. Nair, Jennifer Gray-Beckman
  • Antigenic Targets Of Autoimmune Sensorineural Hearing Loss (AISNHL) And Development Of Tests For Diagnosis And Management Of AISNHL
    Publication number: 20090075268
    Abstract: This invention relates generally to antigens reactive with autoantibodies associated with autoimmune sensorineural hearing loss (AISNHL), and in particular relates to a novel antigen, Inner Ear Supporting Cell Antigen (IESCA) reactive with autoantibodies associated with autoimmune sensorineural hearing loss (AISNHL), and to methods for the detecting therapeutic outcomes in treatment of AISNHL patients, and to methods of detecting genetic lesions in genes encoding for such antigens.
    Type: Application
    Filed: March 25, 2008
    Publication date: March 19, 2009
    Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Thomas E. Carey, Thankam S. Nair, Jennifer Gray Beckman
  • Antigenic targets of autoimmune sensorineural hearing loss (AISNHL) and development of tests for diagnosis and management of AISNHL
    Publication number: 20030082646
    Abstract: This invention relates generally to antigens reactive with autoantibodies associated with autoimmune sensorineural hearing loss (AISNHL), and in particular relates to a novel antigen, Inner Ear Supporting Cell Antigen (IESCA) reactive with autoantibodies associated with autoimmune sensorineural hearing loss (AISNHL), and to methods for the detecting therapeutic outcomes in treatment of AISNHL patients, and to methods of detecting genetic lesions in genes encoding for such antigens.
    Type: Application
    Filed: May 6, 2002
    Publication date: May 1, 2003
    Applicant: The Regents of the University of Michigan
    Inventors: Thomas E. Carey, Thankam S. Nair, Jennifer Gray Beckman
  • IDENTIFYING THE ANTIGENIC TARGET OF AUTOIMMUNE SENSORINEURAL HEARING LOSS (AISNHL) AND DEVELOPEMENT OF SPECIFIC TESTS FOR DIAGNOSIS AND MANAGEMENT OF AISNHL
    Publication number: 20010006788
    Abstract: The substantial purification and characterization of the glycoprotein Inner Ear Supporting Cell Antigen (IESCA) is described, along with methods employing IESCA to detect autoimmune sensorineural hearing loss (AISNHL), agonists and antagonists of IESCA binding and anti-IESCA binding, as well as homologs of IESCA.
    Type: Application
    Filed: December 29, 1998
    Publication date: July 5, 2001
    Inventors: THOMAS E. CAREY, THANKUM S. NAIR, JENNIFER P. GRAY