Patents by Inventor Thomas E. Creighton

Thomas E. Creighton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the production of a protein
    Patent number: 4977248
    Abstract: A method for the renaturation of unfolded proteins comprises reversibly immobilizing the denatured protein on a solid phase and inducing folding of the immobilized protein by progressively reducing with time the concentration of a denaturing agent in the solvent in contact with the solid phase. The refolded protein is recovered from the solid phase in native form. The proteins can be folded and recovered in high yield in a small volume of buffer.
    Type: Grant
    Filed: August 10, 1989
    Date of Patent: December 11, 1990
    Inventor: Thomas E. Creighton