Abstract: Disclosed are novel compositions of matter and treatment methods for reducing and/or reversing epilepsy through administration of mesenchymal stem cells in order to induce immune modulation and/or regenerative processes.

Abstract: Disclosed are means, methods, and therapeutic compositions for prevention of memory loss during situations of neuroinflammation. In one embodiment the invention teaches administration of the therapeutic combination of ingredients comprising of pterostilbene, Nigella sativa, sulforaphane, and epigallocatechin-3-gallate (EGCG) to a mammal suffering from inflammation in order to preserver memory function.

Abstract: The invention discloses the utilization of mesenchymal stem cells, exosomes from mesenchymal stem cells, conditioned media from mesenchymal stem cells, apoptotic bodies from mesenchymal stem cells, and modified mesenchymal stem cells for treatment of bipolar disorder. In one embodiment mesenchymal stem cells isolated from umbilical cord tissue are treated carbon monoxide at a concentration sufficient to induce activation of heme-oxygenase I and infused into a patient at risk or suffering from bipolar disorder.

Abstract: Disclosed are means of inducing pulmonary regeneration and/or protection from oxidative stress by stimulation of endogenous stem cell mobilization together with one or more inhibitors of NF-kappa B and/or one or more inhibitors of oxidative stress. The invention discloses the unexpected finding that G-CSF administration enhances oxidative stress and pulmonary damage, however, coadministration with pterostilbene, results in synergistic suppression of COPD pathology.

Abstract: Disclosed are treatment means, compositions of matter and protocols useful for suppression of acute respiratory disorder (ARDS) through induction of RNA interference in the pulmonary microenvironment alone and/or in conjunction with mucolytic and/or DNA disrupting agents. In one embodiment short interfering RNA (siRNA) is prepared which targets complement receptors C3R and/or C5R together with TNF-receptor, IL-6 receptor and/or TLR4 and TLR9. In some embodiments nanostilbene is utilized as a delivery vehicle for siRNA delivery.

Abstract: A door operating apparatus is provided for safely and efficiently opening and/or closing a side door of a railway boxcar by moving a door engagement member laterally.

Abstract: A door operating apparatus is provided for safely and efficiently opening and/or closing a side door of a railway boxcar by moving a door engagement member laterally.

Abstract: A tree saw includes a frame adapted to be attached to the boom of a prime mover, a tree clamping mechanism on the frame, and a carriage assembly on the frame below the clamping mechanism. The carriage assembly includes a generally plate-like chassis, a generally U-shaped bulkhead upstanding from the chassis and providing a recessed base portion and forwardly-extending arm portions, and a slide mechanism on the arm portions. A rail mechanism on the frame receives the slide mechanism for reciprocating movement of the carriage assembly. A hydraulic cylinder assembly interconnects the bulkhead and frame for reciprocating the carriage assembly. An annular rim member rotatably mounted on the chassis has a geared inner circumference and a toothed outer circumference projecting forwardly of the base portion. A motor-driven pinion mechanism on the chassis engages the rim member inner circumference to rotate the rim member.

Abstract: A quick coupling for connecting a side shift cylinder of a carriage attachment to the lift carriage of a lift truck includes a pair of laterally spaced mounting blocks extending between and welded to the upper and lower cross frame members of the lift carriage to provide a mounting space therebetween. A rear portion of a mounting plate extends into the mounting space, and a pull pin extends through aligned openings of the blocks and plate to removably connect the plate to the lift carriage. A forward portion of the plate projects forwardly beyond and overlaps the front faces of the carriage cross frame members and has an opening therethrough which receives a piston rod extension of the side shift cylinder of the attachment. A second pull pin extends through an opening in the leading end portion of the extension to removably connect the side shift cylinder to the mounting plate.