Patents by Inventor Thomas E. Fisk

Thomas E. Fisk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160195472
    Abstract: The invention is directed to a non-destructive method of detecting whether a coating or deposit (30, 34) of (a) SiOxCy or SiNxCy and/or (b) of SiOx is present on or near a surface of an article (12), such as a disposable thermoplastic medical article. The method includes impinging infrared light (216) having a wave number in at least a portion of a desired range onto at least a first surface being examined for the presence of the one or more coatings or deposits. At least a portion (224) of the infrared light impinged on the first surface is collected (at 222) and the response output, which may include for example the maximum intensity and/or peak area of the collected infrared light at an infrared spectroscopy peak, is used to indicate the presence of the one or more coatings or deposits.
    Type: Application
    Filed: September 12, 2014
    Publication date: July 7, 2016
    Inventors: Thomas E. FISK, Kevin TURNEY, Robert L. BROWNING
  • Patent number: 9272095
    Abstract: Methods for processing a contact surface, for example to provide a gas barrier or lubricity or to modify the wetting properties on a medical device, are disclosed. First and second PECVD or other contact surface processing stations or devices and a contact surface holder comprising a contact surface port are provided. An opening of the contact surface can be seated on the contact surface port. The interior contact surface of the seated contact surface can be processed via the contact surface port by the first and second processing stations or devices. contact surface barrier, lubricity and hydrophobic coatings and coated contact surfaces, for example syringes and medical sample collection tubes are disclosed. A contact surface processing system and contact surface inspection apparatus and methods are also disclosed.
    Type: Grant
    Filed: March 30, 2012
    Date of Patent: March 1, 2016
    Assignee: SIO2 MEDICAL PRODUCTS, INC.
    Inventors: John T. Felts, Thomas E. Fisk, Robert Abrams, John Ferguson, Jonathan Freedman, Robert Pangborn, Peter Sagona
  • Publication number: 20160017490
    Abstract: A method for coating a substrate surface such as a syringe part by PECVD is provided, the method comprising generating a plasma from a gaseous reactant comprising an organosilicon precursor and optionally an oxidizing gas by providing plasma-forming energy adjacent to the substrate, thus forming a coating on the substrate surface by plasma enhanced chemical vapor deposition (PECVD). The plasma-forming energy is applied in a first phase as a first pulse at a first energy level followed by further treatment in a second phase at a second energy level lower than the first energy level. The lubricity, hydrophobicity and/or barrier properties of the coating are set by setting the ratio of the O2 to the organosilicon precursor in the gaseous reactant, and/or by setting the electric power used for generating the plasma.
    Type: Application
    Filed: March 14, 2014
    Publication date: January 21, 2016
    Inventors: Joseph A. Jones, John T. Felts, James Troy Gresham, Brian Russell Lilly, Thomas E. Fisk
  • Publication number: 20150335823
    Abstract: A method and apparatus for plasma modifying a workpiece such as a medical barrel, medical barrel, vial, or blood tube is described. Plasma is provided within the lumen of the workpiece. The plasma is provided under conditions effective for plasma modification of a surface of the workpiece. A magnetic field is provided in at least a portion of the lumen. The magnetic field has an orientation and field strength effective to improve the uniformity of plasma modification of the generally cylindrical interior surface 16 of the generally cylindrical interior surface 16.
    Type: Application
    Filed: November 25, 2013
    Publication date: November 26, 2015
    Inventors: Christopher Weikart, Becky L. Clark, Adam Stevenson, Robert S. Abrams, John Belfance, Joseph A. Jones, Thomas E. Fisk
  • Publication number: 20150316440
    Abstract: An apparatus and methods for testing the integrity of a barrier coating on a vessel. An off gas test fixture includes a face seal positioned about an opening of the vessel. A side seal is positioned about a portion of the vessel's wall and separated from the face seal by a space. Additionally, a cover may be secured to the fixture that encompasses an interface portion of the fixture and the vessel. Before and/or during testing, gas in the space between the side and face seals may be evacuated, as well as gas present in an interior area of the vessel. The vessel may be exposed to test gas(es) that is soluble by the plastic material of the vessel before and/or after being secured to the fixture. During testing, test gas(es) desorbed by the vessel may be evacuated, with the molecular flow being measured using a mass extraction unit.
    Type: Application
    Filed: November 15, 2013
    Publication date: November 5, 2015
    Inventors: Thomas E. Fisk, Peter J. Sagona, Joseph A. Jones
  • Publication number: 20150297800
    Abstract: A vessel including a thermoplastic wall enclosing a lumen is disclosed. The wall supports an SiOx composite barrier coating or layer, for which x is from 1.8 to 2.4, between the wall and the lumen. High Resolution X-ray Photoelectron Spectroscopy (XPS) shows the presence of an interface between the composite barrier coating or layer and the wall or substrate. In one aspect, the interface has at least 1 mol.% O3—Si—C covalent bonding, as a proportion of the O3—Si—C covalent bonding plus SiO4 bonding. In another aspect, the interface has an Si 2p chemical shift to lower binding energy (eV), compared to the binding energy of SiO4 bonding. The result is a tightly adherent composite barrier coating or layer having a high degree of adhesion to the substrate under practical use conditions. Methods of applying the composite barrier coating or layer are also disclosed.
    Type: Application
    Filed: June 28, 2013
    Publication date: October 22, 2015
    Applicant: SIO2 MEDICAL PRODUCTS, INC.
    Inventors: Christopher Weikart, John T. Felts, Thomas E. Fisk, Robert S. Abrams, John Ferguson, Jonathan R. Freedman, Robert J. Pangborn, Peter J. Sagona
  • Publication number: 20150293031
    Abstract: A reflectometry method and other methods for detecting discontinuities in a chemical vapor deposition (CVD) coating are disclosed. The method includes several steps. A thermoplastic vessel wall (710) is provided having an outside surface, an inside surface, and a CVD coating on at least one of the inside and outside surfaces. The vessel wall and the CVD coating have different indices of refraction. Electromagnetic energy (718) is impinged on multiple positions of the CVD coating under conditions effective to cause energy to reflect from the multiple positions of the CVD coating. The reflected energy is analyzed to determine whether the reflected energy includes at least one artifact of a discontinuity in the CVD coating.
    Type: Application
    Filed: October 31, 2013
    Publication date: October 15, 2015
    Applicant: SiO2 Medical Products, Inc.
    Inventor: Thomas E. Fisk
  • Publication number: 20150126941
    Abstract: A method for providing a saccharide based lubricating or protective coating or layer on a substrate surface is provided. In particular, a lubricity and/or protective coating or layer made by said method is provided. Pharmaceutical packages or other vessels coated by said method and the use of such pharmaceutical packages or other vessels protecting a compound or composition contained or received in said vessel with a protective coating against mechanical and/or chemical effects of the surface of the vessel without a protective coating material are also provided.
    Type: Application
    Filed: May 9, 2013
    Publication date: May 7, 2015
    Applicant: SiO2 Medical Products, Inc.
    Inventors: John T. Felts, Thomas E. Fisk, Robert S. Abrams, John Ferguson, Jonathan R. Freedman, Robert J. Pangborn, Peter Sagona, Christopher Weikart, Jacob Israelachvili
  • Publication number: 20150098084
    Abstract: A method for inspecting the product of a coating process is provided. In certain embodiments, the release of at least one volatile species from the coated surface into the gas space adjacent to the coated surface is measured and the result is compared with the result for at least one reference object measured under the same test conditions. Microbalance weighing methods are also disclosed to detect and distinguish among PECVD coatings. Thus the presence or absence of the coating, and/or a physical and/or chemical property of the coating can be determined. The method is useful for inspecting any coated articles, e.g. vessels. Its application on the inspection of PECVD coatings made from organosilicon precursors, especially of barrier coatings, is also disclosed.
    Type: Application
    Filed: May 9, 2013
    Publication date: April 9, 2015
    Applicant: SIO2 Medical Products, Inc.
    Inventors: John T. Felts, Thomas E. Fisk, Robert S. Abrams, John Ferguson, Jonathan R. Freedman, Robert J. Pangborn, Peter J. Sagona, Christopher Weikart
  • Publication number: 20150021339
    Abstract: A method for providing a passivation layer or pH protective coating on a substrate surface by PECVD is provided, the method comprising generating a plasma from a gaseous reactant comprising polymerizing gases. The lubricity, passivation, pH protective, hydrophobicity, and/or barrier properties of the passivation layer or pH protective coating are set by setting the ratio of the O2 to the organosilicon precursor in the precursor feed, and/or by setting the electric power used for generating the plasma. In particular, a passivation layer or pH protective coating made by the method is provided. Pharmaceutical packages coated by the method and the use of such packages protecting a composition contained in the vessel against mechanical and/or chemical effects of the surface of the package without a passivation layer or pH protective coating material are also provided.
    Type: Application
    Filed: November 9, 2012
    Publication date: January 22, 2015
    Applicant: SIO2 Medical Products, Inc.
    Inventors: John T. Felts, Thomas E. Fisk, Robert S. Abrams, John Ferguson, Jonathan R. Freedman, Robert J. Pangborn, Peter J. Sagona, Christopher Weikart
  • Patent number: 8911625
    Abstract: The invention includes a spiral wound module comprising at least one membrane sheet wrapped about a permeate collection tube wherein the membrane sheet (14) comprises a plurality of capillary channels in parallel arrangement with each other and which are in fluid communication with the permeate collection tube (12). Many additional embodiments are disclosed along with methods for making and using the module and corresponding components.
    Type: Grant
    Filed: July 1, 2010
    Date of Patent: December 16, 2014
    Assignee: Dow Global Technologies LLC
    Inventors: Gerald F. Billovits, Thomas E. Fisk, Steven D. Jons, David J. Moll
  • Publication number: 20140295053
    Abstract: Methods for processing a vessel, for example to provide a gas barrier or lubricity, are disclosed. First and second PECVD or other vessel processing stations or devices and a vessel holder comprising a vessel port are provided. An opening of the vessel can be seated on the vessel port. The interior surface of the seated vessel can be processed via the vessel port by the first and second processing stations or devices. Vessel barrier, lubricity and hydrophobic coatings and coated vessels, for example syringes and medical sample collection tubes are disclosed.
    Type: Application
    Filed: June 16, 2014
    Publication date: October 2, 2014
    Inventors: John T. Felts, Thomas E. Fisk, Robert S. Abrams, John Ferguson, Jonathan R. Freedman, Robert J. Pangborn, Peter J. Sagona
  • Publication number: 20140274825
    Abstract: A method for coating a substrate surface such as a syringe part by PECVD is provided, the method comprising generating a plasma from a gaseous reactant comprising an organosilicon precursor and optionally an oxidizing gas by providing plasma-forming energy adjacent to the substrate, thus forming a coating on the substrate surface by plasma enhanced chemical vapor deposition (PECVD). The plasma-forming energy is applied in a first phase as a first pulse at a first energy level followed by further treatment in a second phase at a second energy level lower than the first energy level. The lubricity, hydrophobicity and/or barrier properties of the coating are set by setting the ratio of the O2 to the organosilicon precursor in the gaseous reactant, and/or by setting the electric power used for generating the plasma.
    Type: Application
    Filed: March 14, 2014
    Publication date: September 18, 2014
    Inventors: Joseph A. Jones, John T. Felts, James Troy Gresham, Brian Russell Lilly, Thomas E. Fisk
  • Patent number: 8834954
    Abstract: Methods for processing a vessel, for example to provide a gas barrier or lubricity, are disclosed. First and second PECVD or other vessel processing stations or devices and a vessel holder comprising a vessel port are provided. An opening of the vessel can be seated on the vessel port. The interior surface of the seated vessel can be processed via the vessel port by the first and second processing stations or devices. Vessel barrier, lubricity and hydrophobic coatings and coated vessels, for example syringes and medical sample collection tubes are disclosed. A vessel processing system and vessel inspection apparatus and methods are also disclosed.
    Type: Grant
    Filed: July 12, 2013
    Date of Patent: September 16, 2014
    Assignee: SIO2 Medical Products, Inc.
    Inventors: John T. Felts, Thomas E. Fisk, Robert S. Abrams, John Ferguson, Jonathan R. Freedman, Robert J. Pangborn, Peter J. Sagona
  • Publication number: 20140069202
    Abstract: A medical device comprising a wall, a coating of SiOx, and a piezochromic material is disclosed. The piezochromic material is associated with the wall, and changes its appearance when the wall is exposed to mechanical stress exceeding a threshold intensity. Also disclosed is a method of interrogating a closed medical device for processing damage, comprising at least the acts of providing a closed medical device and inspecting the medical device. The medical device is inspected from the exterior for a change in the appearance of at least some of its piezochromic material that is characteristic of exposure of the wall to mechanical stress exceeding a threshold intensity greater than zero. Optionally in any embodiment inspecting is carried out using a spectrophotometer to determine the change in the color of at least some of its piezochromic material.
    Type: Application
    Filed: March 14, 2012
    Publication date: March 13, 2014
    Inventor: Thomas E. Fisk
  • Publication number: 20130291632
    Abstract: Methods for processing a vessel, for example to provide a gas barrier or lubricity, are disclosed. First and second PECVD or other vessel processing stations or devices and a vessel holder comprising a vessel port are provided. An opening of the vessel can be seated on the vessel port. The interior surface of the seated vessel can be processed via the vessel port by the first and second processing stations or devices. Vessel barrier, lubricity and hydrophobic coatings and coated vessels, for example syringes and medical sample collection tubes are disclosed.
    Type: Application
    Filed: July 12, 2013
    Publication date: November 7, 2013
    Inventors: John T. Felts, Thomas E. Fisk, Robert S. Abrams, John Ferguson, Jonathan R. Freedman, Robert J. Pangborn, Peter J. Sagona
  • Patent number: 8512796
    Abstract: Methods for processing a vessel, for example to provide a gas barrier or lubricity, are disclosed. First and second PECVD or other vessel processing stations or devices and a vessel holder comprising a vessel port are provided. An opening of the vessel can be seated on the vessel port. The interior surface of the seated vessel can be processed via the vessel port by the first and second processing stations or devices. Vessel barrier, lubricity and hydrophobic coatings and coated vessels, for example syringes and medical sample collection tubes are disclosed. A vessel processing system and vessel inspection apparatus and methods are also disclosed, for example using material outgassed from a surface to inspect the properties of a surface coating.
    Type: Grant
    Filed: June 27, 2011
    Date of Patent: August 20, 2013
    Assignee: Si02 Medical Products, Inc.
    Inventors: John T. Felts, Thomas E. Fisk, Robert S. Abrams, John Ferguson, Jonathan R. Freedman, Robert J. Pangborn, Peter J. Sagona
  • Publication number: 20130041241
    Abstract: A method is disclosed in which a vapor-deposited coating or layer is directly or indirectly applied to at least a portion of the internal wall of the barrel of a capped pre-assembly comprising a barrel, optionally a dispensing portion, and a cap. The cap is secured to the barrel and at least substantially isolates the distal opening of the dispensing portion from pressure conditions outside the cap. A vapor-deposited coating or layer is applied directly or indirectly to at least a portion of the internal wall of the barrel while the pre-assembly is capped. The coating or layer is applied under conditions effective to maintain communication from the barrel lumen to the exterior via the front opening, optionally further via the dispensing portion lumen if present, at the end of the applying step. The capped pre-assembly can be pressure tested easily and rapidly, for example with a test duration between 1 and 60 seconds, to determine whether it has container closure integrity.
    Type: Application
    Filed: October 12, 2012
    Publication date: February 14, 2013
    Inventors: John T. Felts, Thomas E. Fisk, Shawn Kinney, Christopher Weikart, Benjamin Hunt, Adrian Raiche, Brian Fitzpatrick, Peter J. Sagona, Adam Stevenson
  • Publication number: 20120123345
    Abstract: A package including a vessel made of cyclic olefin polymer (COP) resin, a CVD coating on a vessel, and a medicament comprising at least one protein, peptide, and/or DNA sequence is disclosed. Methods for processing a vessel, for example to provide lubricity or hydrophobicity, are also disclosed. The interior surface of the seated vessel can be processed via the vessel port by PECVD. Vessel barrier, lubricity and hydrophobic coatings and coated vessels, for example syringes and medical sample collection tubes are disclosed.
    Type: Application
    Filed: September 22, 2011
    Publication date: May 17, 2012
    Inventors: John T. Felts, Thomas E. Fisk, Robert S. Abrams, John Ferguson, Jonathan R. Freedman, Robert J. Pangborn, Peter J. Sagona
  • Publication number: 20120097597
    Abstract: The invention includes a spiral wound module comprising at least one membrane sheet wrapped about a permeate collection tube wherein the membrane sheet (14) comprises a plurality of capillary channels in parallel arrangement with each other and which are in fluid communication with the permeate collection tube (12). Many additional embodiments are disclosed along with methods for making and using the module and corresponding components.
    Type: Application
    Filed: July 1, 2010
    Publication date: April 26, 2012
    Inventors: Gerald Billovits, Thomas E. Fisk, Steven D. Jons, David J. Moll