Abstract: A molecular cryptographic sampling device is disclosed including at least one unique identifying indicia disposed on the molecular cryptographic sampling device, a substrate including at least one depression disposed in or protrusion disposed on a surface of the substrate, at least one polymeric sorbent coating disposed on the at least one depression or protrusion, and at least one molecular encrypted code disposed on the at least one polymeric sorbent coating. The at least one molecular encrypted code includes at least one molecular tag, wherein the at least one molecular encrypted code is uniquely associated with the at least one unique identifying indicia in a database or by a predetermined algorithm.

Abstract: A high aspect ratio vacuum air sampling assembly is disclosed including a first canister module. The canister module includes a high aspect ratio conduit having an aspect ratio of at least 30:1, an inlet disposed at an inlet end of the conduit, and an outlet with an outlet valve disposed at an outlet end of the conduit. The outlet is in fluid communication with the inlet through an internal volume of the conduit. An air sampling train is attached to and in fluid communication with the inlet, and includes an inlet valve, a precision orifice, and a flow controller. The inlet valve and the outlet valve are configured to isolate the internal volume of the conduit from fluid communication with an external environment when the inlet valve and the outlet valve are closed. The assembly may further include a second canister module or more in sequence.

Abstract: A sampling device is disclosed, including a substrate, a reservoir surface disposed on at least a portion of the substrate and configured to retain a liquid, the reservoir surface having a reservoir surface area and being formed of a reservoir surface material, and a Taylor cone emitter portion. The reservoir surface is essentially impermeable. The reservoir surface is essentially non-porous. The sampling device has a decreased loading time to target analyte saturation relative to an otherwise identical comparative sampling device having at least one of a permeable reservoir surface or a porous reservoir surface.

Abstract: A high aspect ratio vacuum air sampling assembly is disclosed including a first canister module. The canister module includes a high aspect ratio conduit having an aspect ratio of at least 30:1, an inlet disposed at an inlet end of the conduit, and an outlet with an outlet valve disposed at an outlet end of the conduit. The outlet is in fluid communication with the inlet through an internal volume of the conduit. An air sampling train is attached to and in fluid communication with the inlet, and includes an inlet valve, a precision orifice, and a flow controller. The inlet valve and the outlet valve are configured to isolate the internal volume of the conduit from fluid communication with an external environment when the inlet valve and the outlet valve are closed. The assembly may further include a second canister module or more in sequence.

Abstract: A solid phase microextraction device is disclosed, including a substrate having a planar surface and a sorbent layer disposed on the planar surface. The planar surface is defined by a base edge, a spray edge disposed distal across the substrate from the base edge, the spray edge including a tapering tip extending away from the base edge, a first lateral edge extending from the base edge to the tapering tip, and a second lateral edge extending from the base edge to the tapering tip, the second lateral edge being disposed distal across the substrate from the first lateral edge. The sorbent layer extends a sampling length from the spray edge toward the base edge and includes sorbent particles. A method for forming the solid phase microextraction device is disclosed, including applying the sorbent layer on the planar surface utilizing at least one of screen printing, stencil printing, or additive manufacturing.

Abstract: A solid phase microextraction device is disclosed, including a substrate having at least one planar surface, a sorbent layer disposed on at least a portion of the at least one planar surface, a tapering tip extending from the substrate, a receptacle mount configured for removable attachment to an emplacement of a receiving device, and a clocking feature configured for fixing a radial orientation of the at least one planar surface with respect to the receiving device. A solid phase microextraction device repository is disclosed including a wall surrounding a chamber, a plurality of orifices disposed in the wall configured to receive and retain the device, and a plurality of clocking feature interfaces disposed in the wall. A solid phase microextraction device manipulator is disclosed, including a manipulator shaft, an emplacement configured to removably engage a receptacle mount, an electrically conductive contact disposed at the emplacement, an ejector, and a clocking feature interface.

Abstract: A Taylor cone emitter device is disclosed, including a substrate, a sorbent layer on at least a portion of the substrate, a Taylor cone emitter portion extending from the substrate, and a reservoir surface configured to retain a liquid and feed the liquid to the Taylor cone emitter portion while a Taylor cone is emitted from the Taylor cone emitter portion. The Taylor cone emitter portion is free of sharp features having an edge or point with a radius of curvature of less than 250 ?m and includes a broadly curved surface having a radius of curvature of at least 300 ?m from which the Taylor cone emanates. A Taylor cone analysis system is disclosed, including an analytical instrument having a sample inlet, the Taylor cone emitter device, and at least one electric field lens configured to tune Taylor cone generation from the Taylor cone emitter portion.

Abstract: A Taylor cone emitter device repository is disclosed including a repository plate, a repository wall extending therefrom, and an array of orifices and an array of clocking feature interfaces disposed therein. The array of orifices receives and retains an array of Taylor cone emitter devices. The array of clocking feature interfaces guide clocking features of the array of Taylor cone emitter devices into predetermined radial orientations. The repository wall peripherally surrounds a substrate chamber configured to receive a microtiter array tray with the array of solid phase microextraction devices each disposed within a separate well of the microtiter array tray. A Taylor cone emitter device repository system is disclosed including the microtiter array tray, the array of Taylor cone emitter devices, and the Taylor cone emitter device repository system. A method for analyzing a population of samples with the Taylor cone emitter device repository system is disclosed.

Abstract: A Taylor cone emitter device automated handler is disclosed including an actuated Taylor cone emitter device manipulator, first, second, and third actuators configured to actuate the device manipulator horizontally, vertically, and between a vertical orientation and a horizontal orientation. The device manipulator includes a shaft, an emplacement configured to removably engage a receptacle mount of a Taylor cone emitter device, an ejector configured to dismount the receptacle mount, and a clocking feature interface configured to guide the Taylor cone emitter device into and fix it in a predetermined radial orientation. The Taylor cone emitter device automated handler is configured to mount the Taylor cone emitter device in the vertical orientation, rotate the Taylor cone emitter device to the horizontal orientation, and present the Taylor cone emitter device to an analytical instrument. A handling system and method for analyzing a sample using the Taylor cone emitter device automated handler are disclosed.

Abstract: A solid phase microextraction device is disclosed, including a substrate having a planar surface and a sorbent layer disposed on the planar surface. The planar surface is defined by a base edge, a spray edge disposed distal across the substrate from the base edge, the spray edge including a tapering tip extending away from the base edge, a first lateral edge extending from the base edge to the tapering tip, and a second lateral edge extending from the base edge to the tapering tip, the second lateral edge being disposed distal across the substrate from the first lateral edge. The sorbent layer extends a sampling length from the spray edge toward the base edge and includes sorbent particles. A method for forming the solid phase microextraction device is disclosed, including applying the sorbent layer on the planar surface utilizing at least one of screen printing, stencil printing, or additive manufacturing.

Abstract: A solid phase microextraction device is disclosed, including a substrate having a planar surface and a sorbent layer disposed on the planar surface. The planar surface is defined by a base edge, a spray edge disposed distal across the substrate from the base edge, the spray edge including a tapering tip extending away from the base edge, a first lateral edge extending from the base edge to the tapering tip, and a second lateral edge extending from the base edge to the tapering tip, the second lateral edge being disposed distal across the substrate from the first lateral edge. The sorbent layer extends a sampling length from the spray edge toward the base edge and includes sorbent particles. A method for forming the solid phase microextraction device is disclosed, including applying the sorbent layer on the planar surface utilizing at least one of screen printing, stencil printing, or additive manufacturing.

Abstract: A solid phase microextraction device is disclosed, including a substrate having at least one planar surface, a sorbent layer disposed on at least a portion of the at least one planar surface, a tapering tip extending from the substrate, a receptacle mount configured for removable attachment to an emplacement of a receiving device, and a clocking feature configured for fixing a radial orientation of the at least one planar surface with respect to the receiving device. A solid phase microextraction device repository is disclosed including a wall surrounding a chamber, a plurality of orifices disposed in the wall configured to receive and retain the device, and a plurality of clocking feature interfaces disposed in the wall. A solid phase microextraction device manipulator is disclosed, including a manipulator shaft, an emplacement configured to removably engage a receptacle mount, an electrically conductive contact disposed at the emplacement, an ejector, and a clocking feature interface.

Abstract: A solid phase microextraction device is disclosed, including a substrate having at least one planar surface, a sorbent layer disposed on at least a portion of the at least one planar surface, a tapering tip extending from the substrate, a receptacle mount configured for removable attachment to an emplacement of a receiving device, and a clocking feature configured for fixing a radial orientation of the at least one planar surface with respect to the receiving device. A solid phase microextraction device repository is disclosed including a wall surrounding a chamber, a plurality of orifices disposed in the wall configured to receive and retain the device, and a plurality of clocking feature interfaces disposed in the wall. A solid phase microextraction device manipulator is disclosed, including a manipulator shaft, an emplacement configured to removably engage a receptacle mount, an electrically conductive contact disposed at the emplacement, an ejector, and a clocking feature interface.

Abstract: A gas chromatography guard column assembly is disclosed including a guard column having an inlet and an outlet. The guard column is disposed in a coil having a column coil aspect ratio of less than 15. A gas chromatography system is disclosed including an oven cavity, a heater assembly, an inlet, a guard column, an analytical column, and a detector. The guard column is in fluid communication with the inlet and is disposed in a guard column coil. The analytical column is in fluid communication with the guard column and is disposed in an analytical column coil. The detector is in fluid communication with the analytical column. The analytical column coil has an analytical column coil central axis aligned with a central axis of the heater assembly, and the guard column coil has a guard column coil central axis remote from the central axis of the heater assembly.

Abstract: A high aspect ratio vacuum air sampling assembly is disclosed including a first canister module. The canister module includes a high aspect ratio conduit having an aspect ratio of at least 30:1, an inlet disposed at an inlet end of the conduit, and an outlet with an outlet valve disposed at an outlet end of the conduit. The outlet is in fluid communication with the inlet through an internal volume of the conduit. An air sampling train is attached to and in fluid communication with the inlet, and includes an inlet valve, a precision orifice, and a flow controller. The inlet valve and the outlet valve are configured to isolate the internal volume of the conduit from fluid communication with an external environment when the inlet valve and the outlet valve are closed. The assembly may further include a second canister module or more in sequence.

Abstract: A molecular cryptographic sampling device is disclosed including at least one unique identifying indicia disposed on the molecular cryptographic sampling device, a substrate including at least one depression disposed in or protrusion disposed on a surface of the substrate, at least one polymeric sorbent coating disposed on the at least one depression or protrusion, and at least one molecular encrypted code disposed on the at least one polymeric sorbent coating. The at least one molecular encrypted code includes at least one molecular tag, wherein the at least one molecular encrypted code is uniquely associated with the at least one unique identifying indicia in a database or by a predetermined algorithm.

Abstract: A solid phase microextraction device is disclosed, including a substrate having a planar surface and a sorbent layer disposed on the planar surface. The planar surface is defined by a base edge, a spray edge disposed distal across the substrate from the base edge, the spray edge including a tapering tip extending away from the base edge, a first lateral edge extending from the base edge to the tapering tip, and a second lateral edge extending from the base edge to the tapering tip, the second lateral edge being disposed distal across the substrate from the first lateral edge. The sorbent layer extends a sampling length from the spray edge toward the base edge and includes sorbent particles. A method for forming the solid phase microextraction device is disclosed, including applying the sorbent layer on the planar surface utilizing at least one of screen printing, stencil printing, or additive manufacturing.

Abstract: A crescent PLOT column is disclosed, including a capillary column having an inlet, an outlet, a bore, and an inner surface surrounding the bore and extending between the inlet and the outlet. A layer of particles is localized on a radial portion of the inner surface. The layer of the particles includes a radial thickness decreasing from a center of the radial portion to a periphery of the radial portion, forming a crescent shape in a radial frame of reference. A method for preparing the crescent PLOT column is disclosed, including loading the capillary column with a fluid including a carrier and particles such that the fluid is contained within the capillary column. The capillary column and the fluid contained within the capillary column are subjected to a centrifugal force. The carrier is removed, and a layer of the particles is localized on the radial portion of the inner surface.

Abstract: A solid phase microextraction device is disclosed, including a substrate having at least one planar surface, a sorbent layer disposed on at least a portion of the at least one planar surface, a tapering tip extending from the substrate, a receptacle mount configured for removable attachment to an emplacement of a receiving device, and a clocking feature configured for fixing a radial orientation of the planar surface with respect to the receiving device. A solid phase microextraction device repository is disclosed including a wall surrounding a chamber, a plurality of orifices disposed in the wall configured to received and retain the device, and a plurality of clocking feature interfaces disposed in the wall. A solid phase microextraction device manipulator is disclosed, including a manipulator shaft, an emplacement configured to removably engage a receptacle mount, an electrically conductive contact disposed at the emplacement, an ejector, and a clocking feature interface.

Abstract: A gas chromatography guard column assembly is disclosed including a guard column having an inlet and an outlet. The guard column is disposed in a coil having a column coil aspect ratio of less than 15. A gas chromatography system is disclosed including an oven cavity, a heater assembly, an inlet, a guard column, an analytical column, and a detector. The guard column is in fluid communication with the inlet and is disposed in a guard column coil. The analytical column is in fluid communication with the guard column and is disposed in an analytical column coil. The detector is in fluid communication with the analytical column. The analytical column coil has an analytical column coil central axis aligned with a central axis of the heater assembly, and the guard column coil has a guard column coil central axis remote from the central axis of the heater assembly.