Patents by Inventor Thomas E Winkler

Thomas E Winkler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Analytical micro-devices for mental health treatment monitoring
    Patent number: 9581536
    Abstract: A lab on a chip device includes a whole blood inlet port and microchannels to transport a whole blood sample or plasma skimmed from the whole blood sample into a detection chamber that includes at least one 3-electrode set of a counter electrode, a working electrode and a reference electrode. The counter electrode, the working electrode and the reference electrode may present bare, unmodified surfaces that are disposed so that clozapine present in the whole blood sample is detected via a reduction-oxidation reaction. Alternatively, the working electrode surface may include catechol grafted to chitosan. A method of detecting analytes and biomarkers includes collecting a whole blood sample, loading the sample into a point-of-care testing (POCT) device that includes at least one working electrode; testing the sample for the occurrence of a redox reaction; and calculating the total oxidative charge when the working electrode is bare or modified as before.
    Type: Grant
    Filed: May 9, 2014
    Date of Patent: February 28, 2017
    Assignees: UNIVERSITY OF MARYLAND, UNIVERSITY OF MARYLAND
    Inventors: Hadar Ben-Yoav, Reza Ghodssi, Gregory F Payne, Deanna L Kelly, Eunkyoung Kim, Thomas E Winkler
  • ANALYTICAL MICRO-DEVICES FOR MENTAL HEALTH TREATMENT MONITORING
    Publication number: 20140332410
    Abstract: A lab on a chip device includes a whole blood inlet port and microchannels to transport a whole blood sample or plasma skimmed from the whole blood sample into a detection chamber that includes at least one 3-electrode set of a counter electrode, a working electrode and a reference electrode. The counter electrode, the working electrode and the reference electrode may present bare, unmodified surfaces that are disposed so that clozapine present in the whole blood sample is detected via a reduction-oxidation reaction. Alternatively, the working electrode surface may include catechol grafted to chitosan. A method of detecting analytes and biomarkers includes collecting a whole blood sample, loading the sample into a point-of-care testing (POCT) device that includes at least one working electrode; testing the sample for the occurrence of a redox reaction; and calculating the total oxidative charge when the working electrode is bare or modified as before.
    Type: Application
    Filed: May 9, 2014
    Publication date: November 13, 2014
    Applicant: University of Maryland
    Inventors: Hadar Ben-Yoav, Reza Ghodssi, Gregory F. Payne, Deanna L Kelly, Eunkyoung Kim, Thomas E Winkler