Patents by Inventor Thomas Elleman

Thomas Elleman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of screening based on the EGF receptor crystal structure
    Publication number: 20080025983
    Abstract: This invention relates to the structure of members of the epidermal growth factor (EGF) receptor family and to receptor/ligand interactions. In particular, it relates to the field of using the EGF receptor family structure to select and screen for compounds that inhibit the formation of active receptor dimers.
    Type: Application
    Filed: August 3, 2007
    Publication date: January 31, 2008
    Inventors: Timothy Adams, Antony Burgess, Thomas Elleman, Thomas Garrett, Robert Jorissen, Meizhen Lou, George Lovrecz, Neil McKern, Edouard Nice, Colin Ward
  • Crystal Structure of Erbb2 and Uses Thereof
    Publication number: 20070281365
    Abstract: More particularly, the present invention relates to the crystal structure of the ErbB2, in particular the crystal structure of an extracellular portion of ErbB2 and to methods of using the crystal and related structural information to screen for and design compounds that interact with ErbB2, or variants of thereof.
    Type: Application
    Filed: October 6, 2003
    Publication date: December 6, 2007
    Inventors: Thomas Garrett, Thomas Elleman, Timothy Adams, Anthony Burgess, Robert Jorissen, Meizhen Lou, George Lovrecz, Neil McKern, Colin Ward
  • Truncated EGF receptor
    Publication number: 20060234343
    Abstract: The present invention relates to truncated EGF receptor molecules that exhibit increased binding affinities for EGFR ligands such as EGF and TGF1. The present invention also relates to methods of screening for EGF receptor ligands and methods of treatment which involve the use of these molecules.
    Type: Application
    Filed: August 22, 2005
    Publication date: October 19, 2006
    Inventors: Colin Ward, Neil McKern, George Lovrecz, Robert Jorissen, Thomas Garrett, Thomas Elleman, Antony Burgess, Timothy Adams, Teresa Domagala, Edouard Nice