Abstract: Systems and methods for repeatable ultrasound using multi-array scanners are disclosed. These techniques include one or more robotic manipulators that couple to one or more multi-array ultrasound scanners to perform ultrasound examinations. The system uses ultrasound data generated by the scanner to generate registration data, which is usable to create movement instructions for the robotic manipulator(s) for controlling movement, positioning, and operation of the scanner, another scanner, or an interventional instrument (e.g., needle). In an example, one robotic manipulator uses a scanner to generate ultrasound data usable to determine positioning and orientation for a second robotic manipulator to insert an interventional instrument or to operate a second scanner. In aspects, the multi-array scanner can generate ultrasound data using a first array, and the ultrasound data is usable to determine where and how to use a second array to generate additional ultrasound data.

Abstract: Ultrasound systems, ultrasound scanners, and methods for determining port health using ultrasound are disclosed. In some embodiments, the ultrasound system includes a display device configured to display a user interface for the ultrasound system and a wearable ultrasound scanner configured to be attached to a patient over a port that is placed inside the patient, where the port is configured to supply fluid to the patient or retrieve additional fluid from the patient. The ultrasound system also includes a processor system configured to generate, based on reflections of ultrasound received by the wearable ultrasound scanner, a health status of the port, and cause the user interface to display the health status of the port.

Abstract: An ultrasound device, ultrasound system and method for performing the same with a multi-array scanner are disclosed. In some embodiments, an ultrasound device includes an array that has a plurality of rows of ultrasonic transducer elements, with the plurality of rows of transducer elements having a first row of transducer element sub-arrays and two or more outer rows of transducer element sub-arrays. The two or more outer rows have at least one row on two opposite sides of the first row of transducer element sub-arrays, and transducer element sub-arrays in first and second rows of transducer element sub-arrays of the one or more outer rows have heights and widths that are different from each other, with the height of each transducer element sub-array corresponding to a lateral dimension and the width corresponding to an elevation dimension perpendicular to the lateral dimension.

Abstract: The present invention refers to polyoxyalkylene based compounds and their manufacturing method as well as compositions containing at least one polyoxyalkylene based compound and at least one active agent. Furthermore, the present invention refers to the manufacture of the compositions of the present invention as well as their use for the treatment of an illness in mammals or humans.

Abstract: Ultrasound devices that include and/or use a multi-dimensional and multi-frequency arrays of transducer elements for use with ultrasound and methods for using the same are disclosed. In some embodiments, an ultrasound device includes: an array having a center row of transducer elements of a first width that operate at a first frequency and two or more outer rows of transducer elements of a second or other widths that operate at a second or other frequencies different than the first frequency. A controller is configured to control the center row of transducer elements and two or more outer rows of transducer elements to operate at a same time or at different times.

Abstract: Ultrasound devices that include and/or use a multi-dimensional and multi-frequency arrays of transducer elements for use with ultrasound and methods for using the same are disclosed. In some embodiments, an ultrasound device includes: an array having a center row of transducer elements of a first width that operate at a first frequency and two or more outer rows of transducer elements of a second or other widths that operate at a second or other frequencies different than the first frequency. A controller is configured to control the center row of transducer elements and two or more outer rows of transducer elements to operate at a same time or at different times.

Abstract: The present invention refers to polyoxyalkylene based compounds and their manufacturing method as well as compositions including at least one polyoxyalkylene based compound and at least one active agent. Furthermore, the present invention refers to the manufacture of the compositions of the present invention as well as their use for the treatment of an illness in mammals or humans.

Abstract: Ultrasound systems and methods that include and/or use interventional instruments (e.g., needles) are disclosed. In some embodiments, the ultrasound system has an interventional instrument having the at least one ultrasound transducer element attached to the interventional instrument and configured for insertion towards the patient anatomy as part of an insertion procedure. The ultrasound system is configured to: determine, during the insertion procedure, an occurrence of a trigger event; instruct, responsive to the determination of the occurrence of the trigger event, the at least one ultrasound transducer element to transmit the additional ultrasound; and determine, based on the reception of the additional ultrasound by the ultrasound scanner, that the interventional instrument is detected.

Abstract: Ultrasound systems, ultrasound scanners, and methods that are used for performing oral procedures. In some embodiments, an ultrasound system includes: an ultrasound scanner including a mouth guard configured to, when inserted into a patient mouth to at least partially cover one or more teeth, transmit ultrasound at a patient anatomy and receive reflections of the ultrasound from the patient anatomy; and a processor system coupled to the ultrasound scanner and configured to generate, based on the reflections of the ultrasound, an assessment of patient health.

Abstract: The present invention relates to a sphingosine-1-phosphate receptor (S1PR) modulator for use in treating a patient suffering from Alzheimer's dementia.

Abstract: Certain embodiments describe a system, method, and apparatus for ultrasound imaging. For example, the system can include a probe comprising a transducer configured to transmit or receive ultrasound waves. The system can also include a display communicatively coupled to the probe and one or more processors. The one or more processors cause the ultrasound system to detect, using the probe, one or more markings of a membrane located on a skin of a patient. The ultrasound system is also caused to determine position of the probe based on the one or more markings. In addition, the ultrasound system is caused to render on the display an indication of the position of the probe.

Abstract: A novel methacrylic copolymer contains units derived from at least one alkyl methacrylate and methacrylamide. The units derived from methacrylamide are present in at least 34 wt.-%, based on the total weight of the methacrylic copolymer. A method can be used for preparing these novel methacylic copolymers. Pharmaceutical compositions, nutraceutical compositions, coated pharmaceutical or nutraceutical dosage forms, as well as nano- or microparticles can contain the methacrylic copolymer. The methacrylic copolymer can be used as a coating, as a carrier, and as a matrix for an amorphous solid dispersion.

Abstract: Systems and methods for adaptive-color imaging in ultrasound technologies are disclosed. In aspects, adaptive-color imaging techniques are used for providing sensitive color images of internal body structures. The ultrasound system transmits waves reflecting off internal organs, with received signals processed into radiofrequency (RF) data. This RF data undergoes a color-imaging process to extract color-flow information, resulting in color-image data for ultrasound imaging. Feedback loops, including an RF-data loop, a color-image-data loop, or a combined loop, allow for continuous adjustments to parameters and filters in the imaging processes, thus refining images with each iteration. The adjustments for adapting parameters can be initiated on a user interface within the ultrasound system. Processors in the ultrasound system can also determine weighted data values for regions in an ultrasound image to evaluate cost functions used to adapt the parameters.

Abstract: An ultrasound system includes an ultrasound scanner configured to transmit ultrasound at a patient anatomy and generate ultrasound data as part of an ultrasound examination. The ultrasound system also includes an ultrasound machine configured to generate, based on the ultrasound data, an ultrasound image. The ultrasound system also includes a processor system implemented to determine features selected from the group consisting of regional features, patient features, clinician features, and ultrasound examination feature. The processor system is implemented to generate, based on the ultrasound image and the features, a patient recommendation.

Abstract: An ultrasound system includes an ultrasound scanner configured to transmit ultrasound at a patient anatomy and generate ultrasound data as part of an ultrasound examination. The ultrasound system also includes an ultrasound machine configured to generate, based on the ultrasound data, an ultrasound image. The ultrasound system also includes a processor system implemented to determine features selected from the group consisting of regional features, patient features, clinician features, and ultrasound examination feature. The processor system is implemented to generate, based on the ultrasound image and the features, a patient recommendation.

Abstract: An ultrasound system includes an ultrasound scanner configured to transmit ultrasound at a patient anatomy and receive reflections of the ultrasound from the patient anatomy. The ultrasound system includes an ultrasound machine configured to generate received data including ultrasound data based on the reflections of the ultrasound and artifact data based on an interferer. The ultrasound system includes a processor system that is implemented to determine an artifact signal that is based on the interferer, determine, based on the artifact signal, one or more artifact characteristics. In some embodiments, the artifact characteristics are selected from the group consisting of an amplitude, a phase, a center frequency, and a bandwidth. The processor system is implemented to generate, based on the artifact characteristics, filter coefficients, and filter, based on the filter coefficients, the received data to suppress the artifact data and recover the ultrasound data.

Abstract: Systems and methods to detect electromagnetic (EM) emissions on ultrasound systems are described. In some embodiments, an ultrasound system includes an ultrasound scanner that is configured to generate ultrasound data based on reflections of ultrasound signals transmitted by the ultrasound scanner. An ultrasound machine is coupled to the ultrasound scanner and configured to generate an ultrasound image based on the ultrasound data. A circuit is coupled to the ultrasound machine and configured to make a determination whether the ultrasound image is corrupted by a noise process.

Abstract: Systems and methods to detect electromagnetic (EM) emissions on ultrasound systems are described. In some embodiments, an ultrasound system includes an ultrasound scanner that is configured to generate ultrasound data based on reflections of ultrasound signals transmitted by the ultrasound scanner. An ultrasound machine is coupled to the ultrasound scanner and configured to generate an ultrasound image based on the ultrasound data. A circuit is coupled to the ultrasound machine and configured to make a determination whether the ultrasound image is corrupted by a noise process.

Abstract: A wearable ultrasound device and method for using the same are disclosed. In some embodiments, the wearable ultrasound device includes an ultrasound transducer configured to transmit ultrasound signals and receive reflected ultrasound based on the ultrasound signals and a fastener configured to secure the wearable ultrasound device proximate to a procedure site. The wearable ultrasound device can also include a processor configured to generate, based on the reflected ultrasound, patient data and a display device implemented to display a visual representation of the patient data.

Abstract: Ultrasound devices that include and/or use a multi-dimensional and multi-frequency arrays of transducer elements for use with ultrasound and methods for using the same are disclosed. In some embodiments, an ultrasound device includes: an array having a center row of transducer elements of a first width that operate at a first frequency and two or more outer rows of transducer elements of a second or other widths that operate at a second or other frequencies different than the first frequency. A controller is configured to control the center row of transducer elements and two or more outer rows of transducer elements to operate at a same time or at different times.